Results 81 to 90 of about 6,225,689 (197)

Clinical significance and heterogeneity of circulating tumor cells and clusters in breast cancer subtypes [PDF]

PeerJ
The marked heterogeneity of breast cancer results in substantial variations in clinical characteristics, metastatic patterns, and prognosis across molecular subtypes.
LiangYu Hao, Lixiang Zheng
doaj   +2 more sources

Computational ranking identifies Plexin-B2 in circulating tumor cell clustering with monocytes in breast cancer metastasis

Nature Communications
Multicellular circulating tumor cell (CTC) clusters can be up to 50 times more efficient than single CTCs in mediating viable metastasis. Here, combining computational ranking and functional determination, we identify the transmembrane protein Plexin-B2 (
Emma Schuster, Nurmaa K. Dashzeveg, Fangjia Tong, Yuzhi Jia, Lamiaa El-Shennawy, Tong Zhang, Andrew D. Hoffman, Reta Birhanu Kitata, Golam Kibria, Youbin Zhang, Joshua R. Squires, Chunlei Zheng, Erika Ramos, Rokana Taftaf, David Scholten, Hannah F. Almubarak, Valery Adorno-Cruz, David P. Sullivan, Carolina Reduzzi, Allegra C. Minor, William Purev-Ochir, Sabina Spahija, Rong Xu, Kalliopi P. Siziopikou, Leonidas C. Platanias, Ami Shah, William A. Muller, William J. Gradishar, Massimo Cristofanilli, Chia-Feng Tsai, Tujin Shi, Huiping Liu   +31 more
doaj   +1 more source

Circulating tumor plasma cells quantification in newly diagnosed transplant ineligible real world multiple myeloma patients: Comparison of single‐platform flow cytometry versus next generation flow

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Circulating tumor plasma cells (CTCs) at diagnosis are independent prognostic markers in newly diagnosed multiple myeloma (NDMM). Flow cytometry (FC) enables sensitive and cost‐effective CTC quantification, but prognostic cut‐offs vary across studies.
Elona Saraci, Alessandra Larocca, Roberto Ria, Silvia Mangiacavalli, Giulia Benevolo, Nicola Giuliani, Renato Zambello, Angelo Belotti, Ilaria Rizzello, Antonietta Pia Falcone, Iolanda Donatella Vincelli, Mariagrazia Michieli, Sonia Ronconi, Patrizia Tosi, Maria letizia Mosca Siez, Alessandro Allegra, Maide Maria Cavalli, Matilde Scaldaferri, Ilaria Fedele, Marco Burdisso, Tania Villanova, Cristina Velluti, Marcello Capriata, Donato Mannina, Anna Maria Cafro, Elisabetta Antonioli, Sonia Morè, Mario Boccadoro, Benedetto Bruno, Sara Bringhen, Mattia D'Agostino   +30 more
wiley   +1 more source

The utility of folate receptor-positive circulating tumor cell in cancer diagnosis in the elderly population

, 2019
Na Li,1 Dingrong Zhong,2 Huang Chen,2 Tiequn Huang,1 Pihua Hou,1 Yinan Zhang,3 Fangling Chen,3 Xiaoping Wang,1 Hongchun Zhang11Department of Medical Health Care; 2Department of Pathology, China-Japan Friendship Hospital, Beijing 100029, People’s ...
Huang T, Hou P, Zhong D, Zhang Y, Zhang H, Chen F, Chen H, Wang X, Li N   +8 more
core  

Epithelial‐to‐mesenchymal transition (EMT) to sarcoma in recurrent lung adenosquamous carcinoma following adjuvant chemotherapy

Thoracic Cancer, 2019
Adjuvant chemotherapy has long been indicated to extend survival in completely resected stage IB to IIIA non‐small cell lung cancer (NSCLC). However, there is accumulating evidence that chemotherapy or chemoradiotherapy can induce epithelial‐to ...
Mau Ern Poh, Chong Kin Liam, Kein Seong Mun, Chee Shee Chai, Chee Kuan Wong, Jiunn Liang Tan, Thian Chee Loh, Ka Kiat Chin   +7 more
doaj   +1 more source

Quantification of Rare Cancer Cells in Patients With Gastrointestinal Cancer by Nanostructured Substrate

Translational Oncology, 2014
Detecting the cancer cells in the peripheral blood, i.e. circulating tumor cell (CTC), have been considered as the “liquid biopsy” and become a particular area of focus.
Boran Cheng, Haibin Song, Shuyi Wang, Chunxiao Zhang, Bibo Wu, Yuanyuan Chen, Fangfang Chen, Bin Xiong   +7 more
doaj   +1 more source

Is Ductal Carcinoma In Situ a Precursor or Low‐Risk Variant of Invasive Breast Cancer? A Population Perspective

International Journal of Cancer, EarlyView.
ABSTRACT Ductal carcinoma in situ (DCIS) is usually detected with mammography screening and assumed to be a precursor of invasive ductal cancer (IDC) of the breast. Yet, despite an approximately 10‐fold increase in the rate of DCIS detection and treatment within 20 years following implementation of mammography screening in the United States, IDC ...
Ismail Jatoi, Adalberto M. Filho, Gretchen Gierach, Hyuna Sung, Philip S. Rosenberg   +4 more
wiley   +1 more source

Fabrication of Formalin-Fixed, Paraffin-Embedded (FFPE) Circulating Tumor Cell (CTC) Block Using a Hydrogel Core-Mediated Method. [PDF]

Micromachines (Basel), 2021
Lee TH, Kim YJ, Rou WS, Eun HS.
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Size-Based Enrichment Technologies for CTC Detection and Characterization

, 2012
The degree of metastatic outspread in malignant disease is one of the leading factors in determining the appropriate course treatment. Circulating tumor cells (CTCs) represent the population of cells that have acquired the means to gain access to the ...
Datar, Ram, Marija Balic, Anthony Williams, Cote, Richard, Ram Datar, Williams, Anthony, Richard Cote, Balic, Marija   +7 more
core   +1 more source