Results 11 to 20 of about 6,225,689 (197)

The biology and clinical potential of circulating tumor cells

Radiology and Oncology, 2019
Tumor cells can shed from the tumor, enter the circulation and travel to distant organs, where they can seed metastases. These cells are called circulating tumor cells (CTCs).
Lozar Taja, Gersak Klara, Cemazar Maja, Kuhar Cvetka Grasic, Jesenko Tanja   +4 more
doaj   +2 more sources

Apoptotic cells promote circulating tumor cell survival and metastasis [PDF]

Communications Biology
During tumor progression and especially following cytotoxic therapy, cell death of both tumor and stromal cells is widespread. Despite clinical observations that high levels of apoptotic cells correlate with poorer patient outcomes, the physiological ...
Cassidy E. Hagan, Valerie M. Sheehan, Charles M. Rezanka, Meijie A. Li, Laura Martínez-Escardó, Kirsteen J. Campbell, Annelise G. Snyder, Mark Headley, Andrew Oberst   +8 more
doaj   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells. [PDF]

Mol Oncol
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Roth D, Neves RPL, Geheb J, Ballmeyer C, Gaßmann N, Andree KC, Sudarsanam M, Driemel C, Örencik C, Franken A, Elmaghraby E, Loosen SH, Christoph R, Schoelch S, Neubauer H, Knoefel WT, Stoecklein NH, Fluegen G.   +17 more
europepmc   +2 more sources

ADAM19 Promotes EMT-Related Changes and Serves as a Prognostic Marker in Circulating Tumor Cells of Renal Cell Carcinoma. [PDF]

Cancer Sci
ADAM19 is associated with EMT‐related malignant phenotypes and NOTCH/NF‐κB pathway activity in RCC and may serve as a prognostic biomarker in CTCs. ABSTRACT Detection of circulating tumor cells (CTCs), particularly characterization of their epithelial‐mesenchymal transition (EMT) phenotypes, may improve prognostic accuracy for malignancies ...
He M, Li M, Ma Y, Chen Z, Guo L, Wang X, Wang W, Chong T, Wang Z.   +8 more
europepmc   +2 more sources

Circulating Tumor Cells (CTC) and Tumor-Derived Extracellular Vesicles (tdEV) [PDF]

, 2023
The observation that increasing circulating tumor cell (CTC) and tumor-derived extracellular vesicle (tdEV) load is directly related to worse clinical outcome of cancer patients is in line with expectations.
Enciso Martinez, A.; id_orcid, Terstappen, L. W.M.M., Nanou, A., Beekman, P.   +3 more
core   +1 more source

Spearman correlation for CCT2 tumor stain score, circulating tumor cell (CTC) count, and time gap.

, 2022
Spearman correlation for CCT2 tumor stain score, circulating tumor cell (CTC) count, and time gap.
Carlos Alemany (12937026), Elizabeth Griffith (1323738), Louis Barr (12937023), Annette R. Khaled (181666), Heba Ghozlan (10169090), Eunkyung Lee (1862767), Na’im Fanaian (8987786), S. A. Litherland (12937032), Amr S. Khaled (8987783), Xiang Zhu (135451), Amanda Cox (5073860), Rebecca Moroose (12937020), Ryan Sause (12937029), Ana Martini (12937017)   +13 more
core   +1 more source

Current Status of Circulating Tumor Cells in Head and Neck Squamous Cell Carcinoma: A Review

, 2023
Objective Circulating tumor cells (CTCs) are found in the blood of patients with cancer, including head and neck squamous cell carcinomas (HNSCCs). The aim is to review the most up-to-date status of CTCs for applications in patients with HNSCC.
Gopalan, Vinod, Lam, Alfred King-Yin, Farhadul Islam, Sharmin Aktar, Islam, Farhadul, Hooman Baghaie, Vinod Gopalan, Aktar, Sharmin, Alfred King‐Yin Lam, Baghaie, Hooman   +9 more
core   +1 more source

Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model [PDF]

, 2020
International audienceTransformation of castration-resistant prostate cancer (CRPC) into an aggressive neuroendocrine disease (CRPC-NE) represents a major clinical challenge and experimental models are lacking.
Brulle-Soumare, Laura, Tramalloni, Dominique, NgoCamus, M., Manaresi, N., Faugeroux, Vincent, Terstappen, Leon, W M M, Manaresi, Nicolo, Pailler, Emma, Hervieu, C., Stoecklein, N.H., Andree, K.C., Fizazi, K., Nicotra, Claudio, Lapierre, Valérie, Brulle-Soumare, L., Farace, F., Deas, O., Marty, V., Hervieu, Céline, Pailler, E., Oulhen, M., Nicotra, C., Cairo, Stefano, Scoazec, J.-Y., Lapierre, V., Marty, Virginie, Scoazec, Jean-Yves, Faugeroux, V., Ngocamus, Maud, Déas, Olivier, Alexandrova, Kamelia, Fizazi, Karim, Terstappen, L.W.M.M., Loriot, Y., Alexandrova, K., Loriot, Yohann, Farace, Françoise, Tramalloni, D., Cairo, S., Judde, J.-G., Stoecklein, Nikolas, H, Andree, Kiki, C, Oulhen, Marianne, Judde, Jean-Gabriel   +43 more
core   +1 more source

Circulating Tumor Cells and Beyond [PDF]

, 2017
As cancer progresses, tumor cells can travel through the blood circulation to form metastasis. These circulating tumor cells (CTC) can be used as a liquid biopsy for the real-time information they carry about the tumor.
Mutter-de Wit, Sanne
core   +2 more sources

Technical Insights into Highly Sensitive Isolation and Molecular Characterization of Fixed and Live Circulating Tumor Cells for Early Detection of Tumor Invasion. [PDF]

PLoS ONE, 2017
Circulating Tumor Cells (CTC) and Circulating Tumor Microemboli (CTM) are Circulating Rare Cells (CRC) which herald tumor invasion and are expected to provide an opportunity to improve the management of cancer patients. An unsolved technical issue in the
Sophie Laget, Lucile Broncy, Katia Hormigos, Dalia M Dhingra, Fatima BenMohamed, Thierry Capiod, Magne Osteras, Laurent Farinelli, Stephen Jackson, Patrizia Paterlini-Bréchot   +9 more
doaj   +1 more source