Results 51 to 60 of about 6,225,689 (197)

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

Performance and pilot clinical validation of MALDITEC-CTC: a circulating tumor cell detection platform using whole-cell MALDI-TOF MS fingerprinting in osteosarcoma

Cancer Cell International
Background Osteosarcoma is a highly metastatic bone malignancy, with hematogenous spread as the leading cause of mortality. Circulating tumor cells (CTCs) offer a minimally invasive window to detect metastatic potential and real-time tumor dynamics ...
Santhasiri Orrapin, Nutnicha Sirikaew, Wararat Chiangjong, Somchai Chutipongtanate, Pimpisa Teeyakasem, Sasimol Udomruk, Sutpirat Moonmuang, Songphon Sutthitthasakul, Petlada Yongpitakwattana, Areerak Phanphaisarn, Pathacha Suksakit, Arnat Pasena, Ratikorn Kamngoen, Jisnuson Svasti, Voraratt Champattanachai, Jongkolnee Settakorn, Dumnoensun Pruksakorn, Parunya Chaiyawat   +17 more
doaj   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Technical aspects of circulating tumor cells (CTC) isolation using molecular sieve [PDF]

, 2017
The article presents the characteristics of circulating tumor cells (CTC) in the context of their enrichment. It presents the possibility of the use of molecular sieves in CTC isolation.
Zdzisław Bogdanowicz, Kowalik, A., Gruszczyński, K., Mariusz Łapiński, Artur Kowalik, Paweł Pastuszka, Bogdanowicz, Z., Krzysztof Gruszczyński, Łapiński, M., Pastuszka, P.   +9 more
core   +1 more source

Research progress on circulating tumor cells and their detection in colorectal cancer

Zhongguo aizheng zazhi, 2015
Colorectal cancer is one of the most common malignant tumors. Though the development of multidisciplinary therapy has largely improved the therapy effects, many patients still died of local recurrence and metastases after surgery. Circulating tumor cell (
孙文洁, 章　真
doaj  

Identification and Single‐Cell Analysis of Viable Circulating Tumor Cells by a Mitochondrion‐Specific AIE Bioprobe

Advanced Science, 2020
Liquid biopsies of cancer via single‐cell molecular profiling of circulating tumor cells (CTCs) are hampered by the lack of ideal CTC markers. In this study, it is reported that TPN, a bioprobe with aggregation‐induced emission (AIE) activity is capable ...
Bo Situ, Xinyi Ye, Qianwen Zhao, Liyao Mai, Yifang Huang, Siqi Wang, Jing Chen, Bo Li, Bairong He, Ye Zhang, Jianjun Zou, Ben Zhong Tang, Xinghua Pan, Lei Zheng   +13 more
doaj   +1 more source

Space Jam‐Ming: Generating Interstitial Space Using Fragmented Granular GelMA to Investigate Novel Paradigms of Cancer Metastasis

Advanced Science, EarlyView.
Microgels enable independent control of stiffness and interstitial space, overcoming limitations of conventional 3D hydrogels. Using fragmented gelatin methacryloyl microgels, we show that stiffness does not restrict non‐metastatic breast cancer growth, contrary to bulk hydrogels, and reveal the role of adherent‐to‐suspension transition in cancer ...
Danielle Vahala, Zhuang Min Lee, Sebastian E. Amos, Dong Woo Son, Jong Hwa Byun, Farzan Navaeipour, Jiayue Li, Kai L. Metzner, Ji Hoon Jeong, Juyeon Kim, Yongsung Hwang, Brendan F. Kennedy, Khoon S. Lim, Hee Seung Lee, Hyun Woo Park, Yu Suk Choi   +15 more
wiley   +1 more source

Targeting the CRYAB/β‐Catenin Axis with an MMP‐9‐Responsive Hydrogel Disrupts CTC Clusters to Suppress Progression of Hepatocellular Carcinoma after Radiofrequency Ablation

Advanced Science, EarlyView.
The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen, Danni Yang, Songying Pi, Yuhan Liu, Hongbin Huang, Feile Ye, Yuhong Lin, Zhongzhen Su, Yongquan Huang   +8 more
wiley   +1 more source

The distribution of CTC-positive samples according to their ER status and received therapy.

, 2013
ER – estrogen receptor; ET – endocrine therapy; CTC – circulating tumor cell.
Volkmar Müller (86722), Julia Spötter (460208), Klaus Pantel (86726), Simon A. Joosse (194244), Anna Babayan (460207), Juliane Hannemann (23632)   +5 more
core   +1 more source