Results 11 to 20 of about 6,048,216 (301)
Detection of Circulating Tumor Cells [PDF]
Scientifica, 2014 The increasing number of treatment options for patients with metastatic carcinomas has created an accompanying need for methods to determine if the tumor will be responsive to the intended therapy and to monitor its effectiveness.
Sanne de Wit +2 more
doaj +5 more sources
Circulating Tumor Cells for Glioma [PDF]
Frontiers in Oncology, 2021 Liquid biopsy has entered clinical applications for several cancers, including metastatic breast, prostate, and colorectal cancer for CTC enumeration and NSCLC for EGFR mutations in ctDNA, and has improved the individualized treatment of many cancers ...
Huikai Zhang +4 more
doaj +3 more sources
Isolation of circulating tumor cells
iScience, 2022 Summary: Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs before, during, and after treatment holds unique potential in ...
Jon F. Edd +6 more
doaj +3 more sources
A fatal affair: Circulating tumor cell relationships that shape metastasis
iScience, 2021 Summary: Circulating tumor cells are metastatic precursors in several cancer types. Their biology and clinical utility are subject to numerous investigations, yet one aspect that is often neglected is their entanglement with the tumor microenvironment ...
Lauren L. Ozimski +2 more
doaj +2 more sources
Surgical Pathology Clinics, 2018 Circulating tumor cells (CTC) play a central role in tumor dissemination and metastases, which are ultimately responsible for most cancer deaths. Technologies that allow for identification and enumeration of rare CTC from cancer patients’ blood have ...
Richard J. Cote +7 more
core +3 more sources
Proceedings of the National Academy of Sciences, 2013 A typical cancerous tumor contains millions or even billions of cells harboring genetic mutations driving them to grow, divide, and invade the local tissue in which they’re embedded. However, as the cells proliferate, they don’t all stay in the neighborhood.
Plaks, Vicki +2 more
openaire +7 more sources
Tumor Hypoxia and Circulating Tumor Cells [PDF]
International Journal of Molecular Sciences, 2020 Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
openaire +5 more sources
Cells, 2021 Circulating tumor cells (CTCs) provide an accessible tool for investigating tumor heterogeneity and cell populations with metastatic potential. Although an in-depth molecular investigation is limited by the extremely low CTC count in circulation ...
Tala Tayoun +4 more
doaj +1 more source
RNA-Based CTC Analysis Provides Prognostic Information in Metastatic Breast Cancer
Diagnostics, 2021 In metastatic breast cancer (MBC) the molecular characterization of circulating tumor cells (CTCs) provides a unique tool to understand metastasis-biology and therapy-resistance.
Areti Strati +3 more
doaj +1 more source
Scientific Reports, 2023 Liquid biopsy (LB) provides a unique minimally invasive tool to follow-up cancer patients over time, to detect minimal residual disease (MRD), to study metastasis-biology and mechanisms of therapy-resistance.
Dimitra Stergiopoulou +8 more
doaj +1 more source