Results 11 to 20 of about 490,680 (293)
Isolation of circulating tumor cells
iScience, 2022 Summary: Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs before, during, and after treatment holds unique potential in ...
Jon F. Edd +6 more
doaj +3 more sources
Circulating Tumor Cells for Glioma [PDF]
Frontiers in Oncology, 2021 Liquid biopsy has entered clinical applications for several cancers, including metastatic breast, prostate, and colorectal cancer for CTC enumeration and NSCLC for EGFR mutations in ctDNA, and has improved the individualized treatment of many cancers ...
Huikai Zhang +4 more
doaj +3 more sources
Metastasis and circulating tumor cells [PDF]
EJIFCC, 2012 Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor ...
Dalum, G. van +2 more
core +4 more sources
Detection of Circulating Tumor Cells [PDF]
Scientifica, 2014 The increasing number of treatment options for patients with metastatic carcinomas has created an accompanying need for methods to determine if the tumor will be responsive to the intended therapy and to monitor its effectiveness.
Sanne de Wit +2 more
doaj +3 more sources
Proceedings of the National Academy of Sciences, 2013 A typical cancerous tumor contains millions or even billions of cells harboring genetic mutations driving them to grow, divide, and invade the local tissue in which they’re embedded. However, as the cells proliferate, they don’t all stay in the neighborhood.
Plaks, Vicki +2 more
openaire +6 more sources
Tumor Hypoxia and Circulating Tumor Cells [PDF]
International Journal of Molecular Sciences, 2020 Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
openaire +5 more sources
JAMA Oncology, 2015 Circulating Tumor Cells (CTC) are shed from primary or secondary tumors. Prior studies have demonstrated that enumeration of CTC is a robust independent prognostic factor of progression free and overall survival in patients with early and metastatic breast cancer.
Costanza, Paoletti, Daniel F, Hayes
openaire +3 more sources
SnapShot: Circulating Tumor Cells [PDF]
Cell, 2017 Circulating tumor cells in the blood of patients are both signal flares for the existence of a tumor and harbingers of metastasis. With recent technological developments, these cells can be isolated and analyzed to provide insights into the biology of cancer spread and response to therapy and to offer new avenues for blood biomarker development.
Caroline, Dive, Ged, Brady
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Circulating tumor cell technologies [PDF]
Molecular Oncology, 2016 Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of CTCs lies in the ability to detect and isolate these rare cells using methods amenable to downstream characterization and other applications. In this review, we will
Meghaan M, Ferreira +2 more
openaire +2 more sources