Results 21 to 30 of about 6,048,216 (301)

The Effect of Genomic DNA Contamination on the Detection of Circulating Long Non-Coding RNAs: The Paradigm of MALAT1

Diagnostics, 2021
The presence of contaminating gDNA in RNA preparations is a frequent cause of false positives in RT-PCR-based analysis. However, in some cases, this cannot be avoided, especially when there are no exons–intron junctions in the lncRNA sequences.
Athina N. Markou, Stavroula Smilkou, Emilia Tsaroucha, Evi Lianidou   +3 more
doaj   +1 more source

KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer

Molecular Oncology, 2021
MLL3 histone methyltransferase, encoded by the KMT2C gene, is a tumor suppressor that has an essential role in cell‐type‐specific gene expression.
Sofia Mastoraki, Ioanna Balgkouranidou, Emily Tsaroucha, Apostolos Klinakis, Vassilis Georgoulias, Evi Lianidou   +5 more
doaj   +1 more source

Circulating tumor cells in genitourinary tumors [PDF]

Therapeutic Advances in Urology, 2017
Management of advanced urogenital malignancies has profoundly changed in recent years due to the development of novel targeted drugs that have significantly improved patient’s clinical outcomes. This process has been made possible mainly thanks to better knowledge of tumor genetic alterations and molecular altered pathways.
Massari, Francesco, Di Nunno, Vincenzo, COMITO, FRANCESCA, CUBELLI, MARTA, Ciccarese, Chiara, Iacovelli, Roberto, Fiorentino, Michelangelo, Montironi, Rodolfo, Ardizzoni, Andrea   +8 more
openaire   +3 more sources

Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients

Scientific Reports, 2021
Liquid biopsy is a tool to unveil resistance mechanisms in NSCLC. We studied changes in gene expression in CTC-enriched fractions of EGFR-mutant NSCLC patients under osimertinib.
Aliki Ntzifa, Areti Strati, Galatea Kallergi, Athanasios Kotsakis, Vassilis Georgoulias, Evi Lianidou   +5 more
doaj   +1 more source

Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook

Molecular Oncology, 2021
Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐time follow‐up of cancer and overcomes many limitations of tissue biopsies.
Evi Lianidou
doaj   +1 more source

Evaluation of Monocarboxylate Transporter 4 (MCT4) Expression and Its Prognostic Significance in Circulating Tumor Cells From Patients With Early Stage Non-Small-Cell Lung Cancer

Frontiers in Cell and Developmental Biology, 2021
Purpose: Monocarboxylate transporter 4 (MCT4) can influence the amount of lactate in the tumor microenvironment and further control cancer cell proliferation, migration, and angiogenesis.
Athina Markou, E. Tzanikou, G. Kallergi, E. Pantazaka, V. Georgoulias, A. Kotsakis, E. Lianidou   +6 more
doaj   +1 more source

Circulating Tumor Cells in Neuroblastoma

Turkish Journal of Hematology, 2017
Mili Jain, Ashutosh Kumar, Sanjay Mishra, Nishant Verma, Madhu Mati Goel   +4 more
doaj   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells. [PDF]

Mol Oncol
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Roth D, Neves RPL, Geheb J, Ballmeyer C, Gaßmann N, Andree KC, Sudarsanam M, Driemel C, Örencik C, Franken A, Elmaghraby E, Loosen SH, Christoph R, Schoelch S, Neubauer H, Knoefel WT, Stoecklein NH, Fluegen G.   +17 more
europepmc   +2 more sources

The Prognostic Significance of Circulating Tumor Cells in Patients with Pancreatobiliary Cancer

, 2023
Background: Circulating tumor cells are cancer cells which separate from the primary tumor and enter systemic circulation. In this study, it was aimed to examine the relationship between circulating tumor cells isolated and identified from the peripheral
Başbınar, Yasemin, Öztop, İlhan, Tarkan Ünek, Uysal, Tuğba, İbrahim Astarcıoğlu, Asim Leblebici, Ünek, İlkay Tuğba, Leblebici, Asım, Hülya Ellidokuz, İlhan Öztop, Tuğba Uysal, Anıl Aysal, Ellidokuz, Hülya, Ibrahim Astarcioglu, Astarcıoğlu, İbrahim, Sağol, Özgül, İlkay Tuğba Ünek, Aysal, ANIL, Anil Aysal, Ece Çakıroğlu, Asım Leblebici, Yaemin Baspinar, Caner Karaca, Yasemin Başbınar, Çakıroğlu, Ece, Karaca, Caner, Ece Cakiroglu, Özgül Sağol, Ünek, Tarkan   +28 more
core   +1 more source

Circulating tumor cells and cholangiocarcinoma [PDF]

Hepatology, 2015
Editorial
Giovannoni R, Villanueva A
openaire   +3 more sources