Results 21 to 30 of about 5,637,645 (256)

The Prognostic Significance of Circulating Tumor Cells in Patients with Pancreatobiliary Cancer

open access: yes, 2023
Background: Circulating tumor cells are cancer cells which separate from the primary tumor and enter systemic circulation. In this study, it was aimed to examine the relationship between circulating tumor cells isolated and identified from the peripheral
Başbınar, Yasemin   +28 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma. [PDF]

open access: yesMol Oncol
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Flach S   +9 more
europepmc   +2 more sources

Clinical Significance of PD-L1 Status in Circulating Tumor Cells for Cancer Management during Immunotherapy

open access: yesBiomedicines, 2023
The approval of monoclonal antibodies against programmed death-ligand 1 (PD-L1) and programmed cell death protein (PD1) has changed the landscape of cancer treatment. To date, many immune checkpoint inhibitors (ICIs) have been approved by the FDA for the
Areti Strati   +3 more
doaj   +1 more source

CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)

open access: yesCells, 2019
Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process.
Tala Tayoun   +5 more
doaj   +1 more source

Detection of Tumor Cell-Specific mRNA in the Peripheral Blood of Patients with Breast Cancer-Evaluation of Several Markers with Real-Time Reverse Transcription-PCR [PDF]

open access: yes, 2013
It is widely known that cells from epithelial tumors, e. g., breast cancer, detach from their primary tissue and enter blood circulation. We show that the presence of circulating tumor cells (CTCs) in samples of patients with primary and metastatic ...
Simone Hofmann   +20 more
core   +1 more source

PD-L1/pS6 in Circulating Tumor Cells (CTCs) during Osimertinib Treatment in Patients with Non-Small Cell Lung Cancer (NSCLC)

open access: yesBiomedicines, 2022
The PD-1/PD-L1 axis provides CTCs an escape route from the immune system. Phosphorylation of the ribosomal protein S6 is implicated in the same pathway, following mTOR activation. The aim of the study was to investigate the expression of PD-L1 and pS6 in
Evangelia Pantazaka   +6 more
doaj   +1 more source

Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support [PDF]

open access: yes, 2004
Background - The mechanisms underlying the variation in collateral formation between patients, even with similar patterns of coronary artery disease, remain unclear.
Bucknall, CA   +15 more
core   +1 more source

Prognostic Significance of TWIST1, CD24, CD44, and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients

open access: yesCells, 2019
(1) Background: The aim of the study was to evaluate the prognostic significance of EMT-associated (TWIST1) and stem-cell (SC) transcript (CD24, CD44, ALDH1) quantification in EpCAM+ circulating tumor cells (CTCs) of early breast cancer patients.
Areti Strati   +3 more
doaj   +1 more source

Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]

open access: yes, 2004
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A.   +5 more
core   +1 more source

In vitro cross-talk between metastasis-competent circulating tumor cells and platelets in colon cancer: a malicious association during the harsh journey in the blood

open access: yesFrontiers in Cell and Developmental Biology, 2023
Background: Platelets are active players in hemostasis, coagulation and also tumorigenesis. The cross-talk between platelets and circulating tumor cells (CTCs) may have various pro-cancer effects, including promoting tumor growth, epithelial-mesenchymal ...
Zahra Eslami-S   +33 more
doaj   +1 more source

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