Results 31 to 40 of about 303,324 (255)

CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)

Cells, 2019
Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process.
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Agathe Aberlenc, Patrycja Pawlikowska, Françoise Farace   +5 more
doaj   +1 more source

Circulating tumor cell technologies [PDF]

Molecular Oncology, 2016
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of CTCs lies in the ability to detect and isolate these rare cells using methods amenable to downstream characterization and other applications. In this review, we will
Meghaan M, Ferreira, Vishnu C, Ramani, Stefanie S, Jeffrey   +2 more
openaire   +2 more sources

PD-L1/pS6 in Circulating Tumor Cells (CTCs) during Osimertinib Treatment in Patients with Non-Small Cell Lung Cancer (NSCLC)

Biomedicines, 2022
The PD-1/PD-L1 axis provides CTCs an escape route from the immune system. Phosphorylation of the ribosomal protein S6 is implicated in the same pathway, following mTOR activation. The aim of the study was to investigate the expression of PD-L1 and pS6 in
Evangelia Pantazaka, Aliki Ntzifa, Argyro Roumeliotou, Evi Lianidou, Vassilis Georgoulias, Athanasios Kotsakis, Galatea Kallergi   +6 more
doaj   +1 more source

Prognostic Significance of TWIST1, CD24, CD44, and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients

Cells, 2019
(1) Background: The aim of the study was to evaluate the prognostic significance of EMT-associated (TWIST1) and stem-cell (SC) transcript (CD24, CD44, ALDH1) quantification in EpCAM+ circulating tumor cells (CTCs) of early breast cancer patients.
Areti Strati, Michail Nikolaou, Vassilis Georgoulias, Evi S. Lianidou   +3 more
doaj   +1 more source

In vitro cross-talk between metastasis-competent circulating tumor cells and platelets in colon cancer: a malicious association during the harsh journey in the blood

Frontiers in Cell and Developmental Biology, 2023
Background: Platelets are active players in hemostasis, coagulation and also tumorigenesis. The cross-talk between platelets and circulating tumor cells (CTCs) may have various pro-cancer effects, including promoting tumor growth, epithelial-mesenchymal ...
Zahra Eslami-S, Zahra Eslami-S, Zahra Eslami-S, Luis Enrique Cortés-Hernández, Luis Enrique Cortés-Hernández, Luis Enrique Cortés-Hernández, Ilias Glogovitis, Ilias Glogovitis, Ilias Glogovitis, Mafalda Antunes-Ferreira, Mafalda Antunes-Ferreira, Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Silvia D’Ambrosi, Silvia D’Ambrosi, Keerthi Kurma, Keerthi Kurma, Keerthi Kurma, Françoise Garima, Françoise Garima, Françoise Garima, Laure Cayrefourcq, Laure Cayrefourcq, Laure Cayrefourcq, Myron G. Best, Myron G. Best, Myron G. Best, Danijela Koppers-Lalic, Thomas Wurdinger, Thomas Wurdinger, Thomas Wurdinger, Catherine Alix-Panabières, Catherine Alix-Panabières, Catherine Alix-Panabières   +33 more
doaj   +1 more source

Liquid Biopsy Analysis as a Tool for TKI-Based Treatment in Non-Small Cell Lung Cancer

Cells, 2022
The treatment of non-small cell lung cancer (NSCLC) has recently evolved with the introduction of targeted therapy based on the use of tyrosine kinase inhibitors (TKIs) in patients with certain gene alterations, including EGFR, ALK, ROS1, BRAF, and MET ...
Karolina Buszka, Aliki Ntzifa, Barbara Owecka, Paula Kamińska, Agata Kolecka-Bednarczyk, Maciej Zabel, Michał Nowicki, Evi Lianidou, Joanna Budna-Tukan   +8 more
doaj   +1 more source

The biology of circulating tumor cells [PDF]

Oncogene, 2015
Metastasis is a biologically complex process consisting of numerous stochastic events which may tremendously differ across various cancer types. Circulating tumor cells (CTCs) are cells that are shed from primary tumors and metastatic deposits into the blood stream.
K Pantel, M R Speicher
openaire   +2 more sources

Circulating Tumor Cells and PET [PDF]

Journal of Nuclear Medicine, 2011
Understanding the distinct molecular features of solid tumors provides the opportunity to develop more targeted and effective therapies. The evaluation and monitoring of these therapies require sophisticated laboratory and imaging technologies to detect potential benefit not necessarily translating into significant changes in tumor size.
Jian Q, Yu, Massimo, Cristofanilli
openaire   +2 more sources

Circulating Tumor Cell and Cell-free Circulating Tumor DNA in Lung Cancer [PDF]

Chonnam Medical Journal, 2016
Circulating tumor cells (CTCs) are tumor cells that are separated from the primary site or metastatic lesion and disseminate in blood circulation. CTCs are considered to be part of the long process of cancer metastasis. As a 'liquid biopsy', CTC molecular examination and investigation of single cancer cells create an important opportunity for providing
Nurwidya, Fariz, Zaini, Jamal, Putra, Andika Chandra, Andarini, Sita, Hudoyo, Achmad, Syahruddin, Elisna, Yunus, Faisal   +6 more
openaire   +2 more sources

Application of circulating tumor cells scope technique on circulating tumor cell research [PDF]

Molecular and Cellular Therapies, 2014
Circulating tumor cells (CTCs) are becoming promising biomarkers in several cancers, such as colon, prostate, and breast carcinomas. Independent research groups have reported a correlation between CTC numbers and patient prognosis. Even more, the development of personalized medicine gives physicians impetus to utilize the advancement of molecular ...
Yang, Dawei, Wang, Lijie, Tian, Xiaochen
openaire   +2 more sources