Results 51 to 60 of about 322,217 (303)
Escape from immunotherapy: possible mechanisms that influence tumor regression/progression [PDF]
, 2004 Tumor escape is one major obstacle that has to be addressed prior to designing and delivering successful immunotherapy. There is compelling evidence to support the notion that immunogenic tumors, in murine models and cancer patients, can be rejected by ...
Ahmad, M, Ali, SA, Rees, RC
core +1 more source
Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]
, 2009 Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core +1 more source
Current Status of Circulating Tumor Cells in Head and Neck Squamous Cell Carcinoma: A Review [PDF]
, 2023 Objective Circulating tumor cells (CTCs) are found in the blood of patients with cancer, including head and neck squamous cell carcinomas (HNSCCs). The aim is to review the most up-to-date status of CTCs for applications in patients with HNSCC.
Gopalan, Vinod +9 more
core +1 more source
Multiplex detection of ten ESR1 mutations and AKT1 E17K in breast cancer using digital PCR
The Journal of Liquid BiopsyIntroduction: ESR1 mutations are now established as a key mechanism of resistance to endocrine therapy in estrogen-receptor–positive breast cancer (ER+ breast cancer) and their sensitive and specific detection in plasma-cell free DNA (plasma-cfDNA) is ...
Stavroula Smilkou +4 more
doaj +1 more source
Molecular Oncology, 2019 Liquid biopsy analysis, mainly based on circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA), provides an extremely powerful tool for the molecular profiling of cancer patients in real time.
Eleni Tzanikou +7 more
doaj +1 more source
A fatal affair: Circulating tumor cell relationships that shape metastasis
iScience, 2021 Summary: Circulating tumor cells are metastatic precursors in several cancer types. Their biology and clinical utility are subject to numerous investigations, yet one aspect that is often neglected is their entanglement with the tumor microenvironment ...
Lauren L. Ozimski +2 more
doaj +1 more source
Affinity-Based Enrichment of Circulating Tumor Cells [PDF]
, 2016 Study of CTC in cancer has always been hampered by its rare existence in blood. In this chapter, we discuss one of first principles employed to capture CTC from cancer patients’ peripheral blood—the affinity-based enrichment of CTC.
Richard J. Cote +5 more
core +1 more source
The Value of Circulating Tumor Cells and Tumor Markers Detection in Lung Cancer Diagnosis
Technology in Cancer Research & Treatment, 2023 Objective Circulating tumor cells are complete tumor cells with multi-scale analysis values that present a high potential for lung cancer diagnosis. To enhance the accuracy of lung cancer diagnosis, we detected circulating tumor cells by the innovated ...
Sumin Guo MD +10 more
doaj +1 more source
Advances in Cancer Biology - Metastasis, 2023 Objectives: In tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) are known to expedite cancer progression (metastasis). CAF-secreted cytokines confer a survival advantage to circulating tumor stem cells (CTSCs) (indicators of residual ...
Sheefa Mirza +3 more
doaj +1 more source
Circulating Tumor Cells, Enumeration and Beyond [PDF]
Cancers, 2010 The detection and enumeration of circulating tumor cells (CTCs) has shown significant clinical utility with respect to prognosis in breast, colorectal and prostate cancers. Emerging studies show that CTCs can provide pharmacodynamic information to aid therapy decision making.
Hou, Jian Mei +6 more
openaire +3 more sources