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Role of circulating tumor DNA and circulating tumor cells in breast cancer: History and updates [PDF]

open access: yes, 2022
Circulating tumor DNA, cell-free DNA, and circulating tumor cells have been at the epitome of recent research in breast cancer. These forms of liquid biopsies have been used in monitoring disease progression, estimating the risk of relapse, and response ...
Zerdan, Maroun Bou   +5 more
core   +1 more source

Liquid Biopsy Analysis as a Tool for TKI-Based Treatment in Non-Small Cell Lung Cancer

open access: yesCells, 2022
The treatment of non-small cell lung cancer (NSCLC) has recently evolved with the introduction of targeted therapy based on the use of tyrosine kinase inhibitors (TKIs) in patients with certain gene alterations, including EGFR, ALK, ROS1, BRAF, and MET ...
Karolina Buszka   +8 more
doaj   +1 more source

Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]

open access: yes, 1967
In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Okada, Shigeru   +5 more
core   +1 more source

The biology of circulating tumor cells [PDF]

open access: yesOncogene, 2015
Metastasis is a biologically complex process consisting of numerous stochastic events which may tremendously differ across various cancer types. Circulating tumor cells (CTCs) are cells that are shed from primary tumors and metastatic deposits into the blood stream.
K Pantel, M R Speicher
openaire   +2 more sources

Circulating Tumor Cells and PET [PDF]

open access: yesJournal of Nuclear Medicine, 2011
Understanding the distinct molecular features of solid tumors provides the opportunity to develop more targeted and effective therapies. The evaluation and monitoring of these therapies require sophisticated laboratory and imaging technologies to detect potential benefit not necessarily translating into significant changes in tumor size.
Jian Q, Yu, Massimo, Cristofanilli
openaire   +2 more sources

Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support [PDF]

open access: yes, 2004
Background - The mechanisms underlying the variation in collateral formation between patients, even with similar patterns of coronary artery disease, remain unclear.
Bucknall, CA   +15 more
core   +1 more source

Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]

open access: yes, 2004
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A.   +5 more
core   +1 more source

Circulating Tumor Cell and Cell-free Circulating Tumor DNA in Lung Cancer [PDF]

open access: yesChonnam Medical Journal, 2016
Circulating tumor cells (CTCs) are tumor cells that are separated from the primary site or metastatic lesion and disseminate in blood circulation. CTCs are considered to be part of the long process of cancer metastasis. As a 'liquid biopsy', CTC molecular examination and investigation of single cancer cells create an important opportunity for providing
Nurwidya, Fariz   +6 more
openaire   +2 more sources

High Sensitivity of Circulating Tumor Cells Derived from a Colorectal Cancer Patient for Dual Inhibition with AKT and mTOR Inhibitors

open access: yesCells, 2020
Circulating tumor cells (CTCs) are cells shed from the primary tumor into the bloodstream. While many studies on solid tumor cells exist, data on CTCs are scarce. The mortality of cancer is mostly associated with metastasis and recent research identified
Daniel J. Smit   +6 more
doaj   +1 more source

Significance of Studying Circulating Tumor Cells

open access: yes, 2016
Circulating Tumor Cells (CTC) are tumor cells released into blood. They are considered the pivotal component of the metastatic cascade and are being extensively studied only in the last decade or so.
Richard J. Cote   +5 more
core   +1 more source

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