Results 61 to 70 of about 6,048,216 (301)
Liquid Biopsy: Detection of Circulating Tumor Cells in Esophageal Squamous Cell Carcinoma
, 2020 Circulating tumor cells (CTC) harvested in the blood of patients with esophageal squamous cell carcinoma (ESCC) are associated with certain clinical pathological parameters as well as patients’ prognosis and response to chemoradiation.
Lam, AK +5 more
core +1 more source
Circulating Tumor Cells, Enumeration and Beyond [PDF]
Cancers, 2010 The detection and enumeration of circulating tumor cells (CTCs) has shown significant clinical utility with respect to prognosis in breast, colorectal and prostate cancers. Emerging studies show that CTCs can provide pharmacodynamic information to aid therapy decision making.
Hou, Jian Mei +6 more
openaire +3 more sources
The Value of Circulating Tumor Cells and Tumor Markers Detection in Lung Cancer Diagnosis
Technology in Cancer Research & Treatment, 2023 Objective Circulating tumor cells are complete tumor cells with multi-scale analysis values that present a high potential for lung cancer diagnosis. To enhance the accuracy of lung cancer diagnosis, we detected circulating tumor cells by the innovated ...
Sumin Guo MD +10 more
doaj +1 more source
Advances in Cancer Biology - Metastasis, 2023 Objectives: In tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) are known to expedite cancer progression (metastasis). CAF-secreted cytokines confer a survival advantage to circulating tumor stem cells (CTSCs) (indicators of residual ...
Sheefa Mirza +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells
, 2016 Circulating tumor cells (CTCs) that detach and migrate from primary tumors are implicated in the metastatic spread of cancer. The identification of CTCs in peripheral blood samples has been associated with poor survival outcomes in various cancer types ...
Ramdane Harouaka +15 more
core +1 more source
The Mechanical Fingerprint of Circulating Tumor Cells (CTCs) in Breast Cancer Patients
, 2021 Circulating tumor cells (CTCs) are a potential predictive surrogate marker for disease monitoring. Due to the sparse knowledge about their phenotype and its changes during cancer progression and treatment response, CTC isolation remains challenging. Here
Bahriye Aktas +4 more
core +1 more source
The International Journal of Biological Markers, 2021 Background: Circulating tumor cells and serum tumor markers have been found significant in predicting outcome for several malignancies. However, their role in gastric cancer is not fully clarified.
Yinxing Zhu +11 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Current detection technologies for circulating tumor cells
, 2017 Circulating tumor cells (CTCs) are cancer cells that circulate in the blood stream after being naturally shed from original or metastatic tumors, and can lead to a new fatal metastasis.
Zheyu Shen +5 more
core +1 more source