This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source
Clinical relevance of perioperative changes in circulating tumor cells in resectable colorectal cancer. [PDF]
Feng Q +7 more
europepmc +1 more source
Detection of circulating tumor cells and microemboli in the blood of lung adenocarcinoma in situ patients case reports. [PDF]
Huang Y +6 more
europepmc +1 more source
Breast cancer stem cells and circulating tumor cells: Dual drivers of progression and relapse. [PDF]
Azizi Z, Er Urganci B, Acikbas I.
europepmc +1 more source
Phenotypic and genotypic characterization of single circulating tumor cells in the follow-up of high-grade serous ovarian cancer. [PDF]
Salmon C +9 more
europepmc +1 more source
Effect of preoperative biliary drainage on peripheral circulating tumor cells after pancreaticoduodenectomy in patients with resectable periampullary carcinoma and obstructive jaundice. [PDF]
Lin H +7 more
europepmc +1 more source
Diagnostic and Prognostic Utility of Cell-Surface Vimentin Positive Circulating Tumor Cells in Breast Cancer Using an Automated Negative Selection Platform. [PDF]
Yeh MH +8 more
europepmc +1 more source
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In most solid tumors, it is distant metastases rather than the primary tumor which limit the prognosis. Distant metastases are caused by circulating tumor cells (CTCs) which actively invade the blood stream, attach to the endothelium in the target organ, invade the surrounding parenchyma, and form new tumors.
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Circulating Tumor Cells and Circulating Tumor DNA
Annual Review of Medicine, 2012Solid tumors derived from epithelial tissues (carcinomas) are responsible for 90% of all new cancers in Europe, and the main four tumor entities are breast, prostate, lung, and colon cancer. Present tumor staging is mainly based on local tumor extension, metastatic lymph node involvement, and evidence of overt distant metastasis obtained by imaging ...
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