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Anatomical, molecular and pathological consideration of the circumventricular organs

Neurochirurgie, 2015
Circumventricular organs (CVOs) are a diverse group of specialised structures characterized by peculiar vascular and position around the third and fourth ventricles of the brain. In humans, these organs are present during the fetal period and some become vestigial after birth.
A Szathmari, A Jouvet, C Mottolese
exaly   +3 more sources

Electrophysiology of the Circumventricular Organs

Frontiers in Neuroendocrinology, 1996
Since the first anatomical description of the circumventricular organs (CVOs) as a structurally distinct group of regions in the central nervous system (CNS), considerable information has implicated these structures as physiologically significant autonomic control centers located at the blood-brain interface.
A V, Ferguson, J S, Bains
openaire   +2 more sources

Circumventricular organs and fever

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1997
We have examined the roles of three circumventricular organs, the area postrema, the subfornical organ, and the organum vasculosum of the lamina terminalis (OVLT), as possible access points for circulating pyrogens to cause fever. In conscious, unrestrained rats prepared with telemetry devices, intracerebroventricular cannulas, and intravenous ...
Y, Takahashi   +3 more
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Vasopressin and sensory circumventricular organs

1999
The subfornical organ, the area postrema and the organum vasculosum of the lamina terminalis are considered to be sensory circumventricular organs as they contain neuronal somata which are located outside the blood-brain barrier and are thus capable of serving as 'sensors' for blood-borne humoral messengers. The endocrine hormone, vasopressin (VP), not
M, Jurzak, H A, Schmid
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Organization of the projections of a circumventricular organ: The area postrema in the rat

Journal of Comparative Neurology, 1983
AbstractThe projections of the rat area postrema were analysed using antero‐grade and retrograde axonal transport techniques. Discrete injections of wheat germ agglutinin conjugated to horseradish peroxidase (WGA‐HRP) into the area postrema produced anterograde labeling in specific medullary and pontine nuclei.
D, van der Kooy, L Y, Koda
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Circumventricular Organs: Gateways to the BrainLeptin Receptors In Hypothalamus And Circumventricular Organs

Clinical and Experimental Pharmacology and Physiology, 2001
SUMMARY1. The adipose tissue‐derived hormone leptin reduces food intake and bodyweight via leptin receptors (Ob‐R) in the hypothalamus.2. Leptin receptor immunoreactivity, demonstrated with an antiserum recognizing all Ob‐R isoforms, is present in hypothalamic neurons of the medial and lateral preoptic area, organum vasculosum lamina terminalis ...
Björn Meister   +1 more
openaire   +1 more source

Circumventricular organs

Neurology, 2011
AP= : area postrema; AQP4= : aquaporin-4; AT1R= : angiotensin type 1 receptor; AVP= : arginine vasopressin; BBB= : blood–brain barrier; CVO= : circumventricular organ; IgG= : immunoglobulin G; IL-6= : interleukin-6; NMO= : neuromyelitis optica; NSCC= : nonspecific cation channel; NTS= : nucleus of the solitary tract ...
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Neurogenesis in the circumventricular organs of adult mouse brains

Journal of Neuroscience Research, 2013
The circumventricular organs (CVOs), including the organum vasculosum of the lamina terminalis (OVLT), subfornical organ (SFO), median eminence (ME), and area postrema (AP), allow parenchyma cells to sense a variety of blood‐derived substances and/or secreted peptides into blood circulation.
Atsushi, Hourai, Seiji, Miyata
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The arcuate nucleus as a circumventricular organ in the mouse

Neuroscience Letters, 2011
The present study searched for morphological correlates of the permeability of the ventromedial arcuate nucleus of the mouse to blood-borne proteins. First, we determined that highly permeable microvessels are detected in the ventromedial arcuate nucleus using a rat monoclonal antibody to a mouse-specific endothelial phenotype (clone MECA32) recently ...
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The Circumventricular Organs and the Central Actions of Angiotensin

Neuroendocrinology, 2008
This review discusses the central nervous system actions of the circulating hormone, angiotensin II. Access of this peptide likely is limited to thoses central structures which lack the blood-brain barrier. Three of the circumventricular organs, the area postrema, the subfornical organ, and the organum vasculosum, have all been suggested to be sites of
openaire   +2 more sources

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