Results 21 to 30 of about 303,751 (297)

Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis

Nature Communications, 2023
Hepatocellular carcinoma (HCC) is the 3rd most deadly malignancy. Activated hepatic stellate cells (aHSC) give rise to cancer-associated fibroblasts in HCC and are considered a potential therapeutic target.
Sonal Sinha, Satoka Aizawa, Yasuhiro Nakano, Alexander Rialdi, Hye Yeon Choi, Rajan Shrestha, Stephanie Q. Pan, Yibu Chen, Meng Li, Audrey Kapelanski-Lamoureux, Gregory Yochum, Linda Sher, Satdarshan Paul Monga, Anthoula Lazaris, Keigo Machida, Michael Karin, Ernesto Guccione, Hidekazu Tsukamoto   +17 more
doaj   +1 more source

CIRRHOSIS WITH PIGMENTATION. [PDF]

JAMA: The Journal of the American Medical Association, 1901
The cases of cirrhosis of the liver with pigmentation of the skin or tissues, or of both together, constitute a small but most interesting group. There has been a great deal of speculation as to the etiology of these cases. The purpose of this paper is to present as briefly as possible the history of this form of cirrhosis, the clinical symptoms and ...
openaire   +3 more sources

Autologous Bone Marrow Infusion Activates the Progenitor Cell Compartment in Patients with Advanced Liver Cirrhosis

Cell Transplantation, 2010
Several clinical trials of bone marrow cell infusion in patients with liver cirrhosis (LC) have shown clinical improvement, despite conflicting results from animal models.
Ja Kyung Kim, Young Nyun Park, Jin Seok Kim, Mi-Suk Park, Yong Han Paik, Jae-Yeon Seok, Yong Eun Chung, Hyun Ok Kim, Kyung Sik Kim, Sang Hoon Ahn, Do Young Kim, Myeong-Jin Kim, Kwan Sik Lee, Chae Yoon Chon, Soo Jeong Kim, Shuji Terai, Isao Sakaida, Kwang-Hyub Han   +17 more
doaj   +1 more source

Regression of liver fibrosis: evidence and challenges

Chinese Medical Journal, 2020
. It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This article systematically summarizes the evidence of fibrosis regression based on histology, liver stiffness, and serum biomarkers, and discusses several ...
Ya-Meng Sun, Shu-Yan Chen, Hong You, Qiang Shi   +3 more
doaj   +1 more source

Pipeline for precise insoluble matrisome coverage in tissue extracellular matrices

Frontiers in Bioengineering and Biotechnology, 2023
The extracellular matrix (ECM) is assembled by hundreds of proteins orchestrating tissue patterning and surrounding cell fates via the mechanical–biochemical feedback loop.
Wei Chen, Wei Chen, Wen Zhang, Wen Zhang, Ning Zhang, Ning Zhang, Shuyan Chen, Shuyan Chen, Tao Huang, Tao Huang, Hong You, Hong You   +11 more
doaj   +1 more source

CIRRHOSIS OF THE LIVER. [PDF]

The Lancet, 1895
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Correlation of Serum Cardiac Markers with Acute Decompensating Events in Liver Cirrhosis

Gastroenterology Research and Practice, 2020
Background and Aim. Liver cirrhosis is often accompanied by insidious cardiac dysfunction. This retrospective cross-sectional study is aimed at exploring the correlation between serum cardiac markers and decompensating events in liver cirrhosis. Methods.
Miaomiao Li, Zeqi Guo, Dan Zhang, Xiangbo Xu, Fernando Gomes Romeiro, Andrea Mancuso, Jingqiao Zhang, Ruirui Feng, Xinmiao Zhou, Cen Hong, Xingshun Qi   +10 more
doaj   +1 more source

IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma

Advanced Science, 2021
Intrahepatic cholangiocarcinoma (ICC) is highly heterogeneous. Here, the authors perform exome sequencing and bulk RNA sequencing on 73 tumor regions from 14 ICC patients to portray the multi‐faceted intratumor heterogeneity (ITH) landscape of ICC.
Xiao Xiang, Ziyang Liu, Chong Zhang, Zhao Li, Jie Gao, Changkun Zhang, Qi Cao, Jinghui Cheng, Hengkang Liu, Dingbao Chen, Qian Cheng, Ning Zhang, Ruidong Xue, Fan Bai, Jiye Zhu   +14 more
doaj   +1 more source

Serum Mac-2-binding protein glycosylation isomer predicts esophagogastric varices in cirrhotic patients with chronic hepatitis C virus infection treated with IFN-free direct-acting antiviral agent: M2BPGi levels predict varices in SVR patients

Annals of Hepatology, 2020
Introduction and objectives: We examined whether Mac-2-binding protein glycosylation isomer (M2BPGi) levels could be a predictive marker for the presence of esophagogastric varices (EGV) in cirrhotic patients after hepatitis C virus (HCV) eradication ...
Kanako Kikukawa, Sawako Uchida-Kobayashi, Akihiro Tamori, Kanako Yoshida, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Atsushi Hagihara, Hideki Fujii, Hiroyasu Morikawa, Masaru Enomoto, Yoshiki Murakami, Norifumi Kawada   +12 more
doaj  

Editorial: Treatment and prognostic assessment of liver cirrhosis and its complications, volume II [PDF]

Frontiers in Medicine
Wei Zhang, Yufu Tang, Hao Wu, Andrea Mancuso, Thierry Thévenot, Xingshun Qi   +5 more
doaj   +2 more sources