Results 171 to 180 of about 202,668 (261)

Vonoprazan as an adjuvant to cisplatin: enhancing antitumor efficacy while mitigating nephrotoxicity and gastrointestinal adverse effects. [PDF]

Front Pharmacol
Alenezi FN, Abdelmageed ME, Nader MA, Zaghloul MS.   +3 more
europepmc   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

Head &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun, Seyoung Seo, Jang Ho Cho, Keon‐Uk Park, Sang‐Cheol Lee, Yong Won Choi, Tak Yun, Seong Hoon Shin, Sung‐Bae Kim, Seungeun Lee, Chang Ho Ahn, Bhumsuk Keam   +11 more
wiley   +1 more source

Simvastatin Restores Cisplatin Sensitivity by Suppressing the Caveolin-1-Mediated PI3K/AKT Signaling Pathway in Cisplatin-Resistant Cervical Cancer Cells. [PDF]

FASEB J
Zhou Y, Liu H, Pan S, Ruan L, Ruan J, Chen J, Ji H, Zhu X.   +7 more
europepmc   +1 more source

Clinicogenomic Features and Outcomes of Adenoid Cystic Carcinoma With Central Nervous System Metastases: A Single‐Institution Cohort Study

Head &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is a rare malignancy with a propensity for perineural invasion and hematogenous spread. Central nervous system (CNS) involvement is uncommon, and detailed clinical and genomic data on this aspect of the disease remain limited.
Omar Elghawy, Jack Stylli, Martin Kurian, Eitan Halper‐Stromberg, Aditi Singh, Christopher D'Avella, Lee Hartner, Roger B. Cohen   +7 more
wiley   +1 more source

Reprogramming Transcriptional Networks via CREB1 Lactylation at K122 Activates HMGB1-Mediated NETosis and Chemoresistance. [PDF]

Int J Biol Sci
Wang JM, Zhao FY, Zhang Q, Yuan Y, Li BQ, Liu N, Li JJ, Liu C, Wang HQ.   +8 more
europepmc   +1 more source

Robotic‐Assisted Extended Sistrunk Approach (RESA) for Salvage Surgery After Head and Neck Irradiation

Head &Neck, EarlyView.
ABSTRACT Background The robotic‐assisted extended “Sistrunk” approach (RESA) is a minimally invasive technique providing access to hypopharyngeal and laryngeal structures via a submental incision and vallecular pharyngotomy, bypassing the base of tongue.
Bartosz Wojtera, Avinash Beharry, Karma Lambercy, Pascaline Dübi, Jelena Todic, Christian Simon   +5 more
wiley   +1 more source

CDK4 Mediates Cisplatin Resistance in Renal Cell Carcinoma (RCC) Cells by Regulating the ASH1L-CTR1 Axis. [PDF]

Oncol Res
Zeng W, Li X, Cai H, Zhou Q, Sun S, Li P, Li S, Chen Z.   +7 more
europepmc   +1 more source

Treatment With the Shaker Head‐Lift Exercise in Head and Neck Cancer Patients With Radiation‐Induced Dysphagia: 12‐Month Results on Swallowing Function From a Randomized, Controlled Trial

Head &Neck, EarlyView.
ABSTRACT Background Dysphagia is a common side‐effect after radiotherapy in head and neck cancer patients. This randomized study aimed to evaluate the effect of the shaker head‐lift exercise (HLE) after 12 months with flexible endoscopic evaluation of swallowing (FEES). Methods Patients were randomly assigned to the intervention (n = 30) or the control
Signe Rödseth Smith, Caterina Finizia, Kerstin Petersson, Lisa Tuomi   +3 more
wiley   +1 more source

YAP inactivation-mediated autophagy inhibition contributes to cisplatin resistance in ovarian cancer cells. [PDF]

J Ovarian Res
Nguyen NT, Hsieh MR, Nguyen HDH, Chimphlee W, Visitsattapongse S, Chiu WT.   +5 more
europepmc   +1 more source