Results 11 to 20 of about 26,491 (207)

Citalopram inhibits platelet function independently of SERT-mediated 5-HT transport [PDF]

Scientific Reports, 2018
Citalopram prevents serotonin (5-HT) uptake into platelets by blocking the serotonin reuptake transporter (SERT). Although some clinical data suggest that selective serotonin reuptake inhibitors (SSRIs) may affect haemostasis and thrombosis, these poorly-
Harvey G. Roweth, Ruoling Yan, Nader H. Bedwani, Alisha Chauhan, Nicole Fowler, Alice H. Watson, Jean-Daniel Malcor, Stewart O. Sage, Gavin E. Jarvis   +8 more
doaj   +4 more sources

Decreased citalopram concentration caused by enzyme induction effect of rifampin: a case report

Therapeutic Advances in Psychopharmacology
Citalopram is a selective serotonin reuptake inhibitor used to treat depression and various anxiety disorders, which is mainly metabolized by the P450 (CYP) enzyme.
Jiajia Liu, Jinmeng Li, Ren Zheng, Ruoying Zhang   +3 more
doaj   +2 more sources

Distribution of citalopram enantiomers following medication with racemic citalopram - a naturalistic therapeutic drug monitoring study. [PDF]

Eur J Clin Pharmacol
Purpose There are very few reports describing to which extent sex, age, dose and time from dose intake affect the enantiomeric distribution during treatment with citalopram.
Espnes KA, Hønnås A, Skogvoll E, Spigset O.   +3 more
europepmc   +2 more sources

Effects of nicorandil on QT prolongation and myocardial damage caused by citalopram in rats.

, 2023
Citalopram is a selective serotonin re-uptake inhibitor (SSRI) antidepressant; it exhibits the greatestcardiotoxic effect among SSRIs. Citalopram can cause drug-induced long QT syndrome (LQTS) andventricular arrhythmias.
Samar Ahmed, Ergur, Bekir Ugur, Akan, Pinar, Akturk, Gozde, Ozlem Gursoy Doruk, Nil Hocaoglu, Serap Cilaker Micili, Micili, Serap Cilaker, Bekir Ugur Ergur, Kalkan, Sule, Hocaoglu, Nil, Gursoy Doruk, Ozlem, Gozde Akturk, Pinar Akan, Ahmed, Samar, Sule Kalkan, CİLAKER MIÇILI, SERAP, HOCAOĞLU AKSAY, NİL   +17 more
core   +2 more sources

Review: Escitalopram—translating molecular properties into clinical benefit: reviewing the evidence in major depression [PDF]

, 2010
The majority of currently marketed drugs contain a mixture of enantiomers; however, recent evidence suggests that individual enantiomers can have pharmacological properties that differ importantly from enantiomer mixtures.
Taylor, David, Leonard, Brian, Taylor, David; id_orcid   +2 more
core   +1 more source

Risk of suicide during treatment with venlafaxine, italopram, fluoxetine, and dothiepin : retrospective cohort study [PDF]

, 2006
Objective To compare the risk of suicide in adults usingthe antidepressant venlafaxine compared with citalopram, fluoxetine, and dothiepin. Design Retrospective cohort study. Setting UK General Practice Research Database. Participants 219 088 patients,
Tennis, Pat, Mines, Daniel, Rubino, Annalisa, Roskell, Neil, Andrews, Elizabeth, Weich, Scott   +5 more
core   +1 more source

Nefopam Hydrochloride: A Fatal Overdose [PDF]

, 2015
Nefopam is a non-opiate analgesic commonly used for the treatment of moderate to severe pain. A case of a 37-year-old male who was found dead in the morning is presented. An autopsy was performed and femoral venous blood, heart blood, urine, and vitreous
L. Nitin Seetohul, Drummond, Gail, Drummond, G., Nitin Seetohul, L., Gail Drummond, De Paoli, Giorgia; id_orcid, Seetohul, L. N., Seetohul, L. Nitin, Giorgia De Paoli, De Paoli, Giorgia, Maskell, Peter D., Peter D. Maskell, De Paoli, G., Seetohul, LN, Maskell, PD, De Paoli, G, Drummond, G   +16 more
core   +1 more source

Postmortem Tissue Distribution of Citalopram in a Case of Carbon Monoxide Poisoning

Arab Journal of Forensic Sciences & Forensic Medicine, 2020
Citalopram abuse may impair judgment and increase the risk of suicidal thoughts. This case report aims to study the postmortem tissue distribution of citalopram in a case of carbon monoxide poisoning.
Magbool E. Oraiby, Mohammed Y. Albeishy, Mohammedalbadr M. Khawaji, Mohammed A. Arishy, Ibraheem M. Attafi   +4 more
doaj   +1 more source

Usefulness of serotoninergic challenge with oral citalopram [PDF]

Brazilian Journal of Psychiatry, 2006
OBJECTIVE: Challenge tests designed to evaluate serotoninergic pathways have widely used intravenous citalopram. Oral citalopram has also been used, but unsatisfactory results were obtained with a dose of 20 mg.
Paulo Mattos, Vanessa A Franco, François Noel, Daniel Segenreich, José Carlos Gonçalves   +4 more
doaj   +1 more source

The Effects of the Adenosine Receptor Antagonists on the Reverse of Cardiovascular Toxic Effects Induced by Citalopram In-Vivo Rat Model of Poisoning

Balkan Medical Journal, 2015
Background: Citalopram is a selective serotonin reuptake inhibitor that requires routine cardiac monitoring to prevent a toxic dose. Prolongation of the QT interval has been observed in acute citalopram poisoning.
Müjgan Büyükdeligöz, Nil Hocaoğlu, Kubilay Oransay, Yeşim Tunçok, Şule Kalkan   +4 more
doaj   +1 more source