Results 21 to 30 of about 43,016 (203)

Combination of Citalopram and Nortriptyline in the Treatment of Obsessive-Compulsive Disorder: A Double – Blind, Placebo-Controlled Trial [PDF]

Iranian Journal of Psychiatry, 2006
Objective: The fact that some antidepressants with strong effects on serotonin reuptake blockade fail to relieve obsessive-compulsive symptoms has caused growing interest in investigating noradrenergic function in obsessive-compulsive disorder (OCD) . In
Firoozeh Raisi, Marzieh Tavakoli, Abbas Ali Nasehi   +2 more
doaj   +1 more source

Usefulness of serotoninergic challenge with oral citalopram [PDF]

Brazilian Journal of Psychiatry, 2006
OBJECTIVE: Challenge tests designed to evaluate serotoninergic pathways have widely used intravenous citalopram. Oral citalopram has also been used, but unsatisfactory results were obtained with a dose of 20 mg.
Paulo Mattos, Vanessa A Franco, François Noel, Daniel Segenreich, José Carlos Gonçalves   +4 more
doaj   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Towards the clinical implementation of pharmacogenetics in bipolar disorder. [PDF]

, 2014
BackgroundBipolar disorder (BD) is a psychiatric illness defined by pathological alterations between the mood states of mania and depression, causing disability, imposing healthcare costs and elevating the risk of suicide.
A Berghofer, A Heils, A Koski, A Serretti, A Serretti, A Serretti, A Szczepankiewicz, A Yu, AA Nierenberg, AK Malhotra, AL Zackrisson, B Alsina, B Kremeyer, C Cordon-Cardo, C Kawanishi, C O’Dushlaine, C Sears, CA Grimes, CC Zai, CE Begley, CH Chen, DA Mrazek, DE Adkins, DJ Smith, DK Hall-Flavin, DK Hall-Flavin, DL Braff, E Lessard, E Schaeffeler, EB Binder, EB Brown, EG Jonsson, EJ Peters, EK Green, EM Penas-Lledo, EM Penas-Lledo, EN Smith, ER Mardis, Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Working Group, F Asztely, F Benedetti, F Czerwensky, F Holsboer, F Mamdani, FJ Gonzalez, FJ McMahon, FM Daray, FP Bymaster, FP Guengerich, FR Sallee, G Shaltiel, G Turecki, GE Simon, GENDEP Investigators, MARS Investigators, STAR*D Investigators, GR Lewin, GS Malhi, GS Sachs, H Pei, HA Garriock, HK Kroemer, I Johansson, IC Gray, J Brockmoller, J de Leon, J de Leon, J de Leon, J de Leon, J Kirchheiner, J Kirchheiner, J Thome, J Winner, JA Engelman, JA Johnson, JA Lieberman, JC Ballenger, JC Chambers, JC Stingl, JE Kootstra-Ros, JE Sarginson, JK Rybakowski, JK Rybakowski, JM Beaulieu, John R Kelsoe, JP Zhang, JP Zhang, JR Kelsoe, JS Leeder, JT Groves, K Herrlin, K Hodgson, K Yoshii, KG Mountjoy, KL Kopnisky, KR Crews, KW Lobello, L Bertilsson, L Michelon, L Tondo, LA Smith, LN Yatham, LV Kessing, M Adli, M Dmitrzak-Weglarz, M Gex-Fabry, M Ingelman-Sundberg, M Man, M Ramsjo, M Sanford, M Tseng, M Uhr, MA Kohli, MA Martin, MD Ritchie, ME van den Akker-van Marle, MH Tsai, Michael J McCarthy, MJ Arranz, MJ McCarthy, MJ Neville, ML Dahl, Naji C Salloum, OL de Klerk, OV Olesen, P Grof, P Huezo-Diaz, P Sklar, PS Klein, Psychiatric GWAS Consortium Bipolar Disorder Working Group, R Calati, R Hashimoto, RA Philibert, RC Kessler, RH Perlis, RH Perlis, RH Perlis, RH Perlis, RH Weisler, RJ Loos, RM Hirschfeld, RM Post, RS Seelan, S Horstmann, S Kapur, S Kapur, S Mallal, S Paddock, S Steinberg, S Ulrich, SC Sim, SG Leckband, SH Sindrup, SI Hung, SJ Gardiner, SL McElroy, Susan G Leckband, SV Ambudkar, T Bremer, T Masui, T Rau, T Ritchie, T Suppes, TD Gould, TE Klein, TL Horvath, V De Luca, VL Ellingrod, W Steimer, WB Denny, WH Chung, YF Lin, YF Zou, Z Wang, Z Wang   +172 more
core   +3 more sources

Cardiovascular Outcomes Associated With Clinical Use of Citalopram and Omeprazole: A Nationwide Population‐Based Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Recent studies have raised concerns about the reduced efficacy of citalopram when used concurrently with proton pump inhibitors. The aim of this study was to evaluate the associations between clinical use of citalopram and omeprazole and the ...
Wen‐Tung Wu, Chun‐Teng Tsai, Yu‐Ching Chou, Po‐Ming Ku, Yong‐Chen Chen, San‐Lin You, Chi‐Feng Hung, Chien‐An Sun   +7 more
doaj   +1 more source

Antidepressants stimulate population growth in the harpacticoid copepod Nitocra spinipes [PDF]

, 2020
Like many pharmaceuticals, antidepressants are designed in such a way that they do not degrade easily. Due to their limited breakdown capabilities, they often enter sewage systems in their active form and may even end up in the environment.
De Schamphelaere, Karel, Koch, Josef
core  

Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]

, 2011
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Anne Claxton, Cheng-Fang Hsieh, Gillian E Mead, Graeme J Hankey, Mansur A Kutlubaev, Maree L Hackett, Rebecca Lee   +6 more
core   +1 more source

Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo. [PDF]

, 2013
In this study, we characterized early biochemical changes associated with sertraline and placebo administration and changes associated with a reduction in depressive symptoms in patients with major depressive disorder (MDD).
Bogdanov, MB, Boyle, SH, Churchill, E, Delnomdedieu, M, Fiehn, O, Kaddurah-Daouk, R, Krishnan, RR, Pickering, E, Rush, AJ, Wang, Z, Wikoff, WR, Zhu, H   +11 more
core   +2 more sources

Torsade de pointes caused by citalopram during the pacemaker battery‐depletion phase: A case report

Annals of Noninvasive Electrocardiology, 2022
Drug‐induced QT prolongation, primarily antiarrhythmic drugs, is a common cause of torsade de pointes (TdP). Although there have been previous reports of drug‐induced TdP in patients, it has not been well documented when caused by citalopram during the ...
Junwen Wang, Ziyi Sun, Siming Tao
doaj   +1 more source

Interventions for treating depression after stroke [PDF]

, 2008
Background: Depression is an important consequence of stroke that impacts on recovery yet is often not detected or inadequately treated. This is an update of a Cochrane review first published in 2004.
Agnoli, Ahrens, Aizawa, American Psychiatric Association, American Psychiatric Association, Andersen, Andersen, Andersen, Andersen, Andersen, Anderson, Annonymous, Astrom, Atarashi, Balunov, Bao, Battaglia, Battaglia, Bautz-Holter, Beck, Berrol, Burvill, Burvill, Burvill, Carson, Casella, Chan, Chen, Chen, Chen, Chen, Cheng, Cheng, Choi-Kwon, Choi-Kwon, Christie, Corr, Corr, Cui, Cullum, Davis, Deans, Dennis, Dennis, Desrosiers, Deutsch, Dong, Drummond, Du, Duval, Ebrahim, Evans, Evans, Feng, Feng, Fengqi, Folstein, Fruehwald, FX Project for Phase III Study, Gekht, Gekht, Gill, Goldberg, Gompertz, Gonzalez-Torrecillas, Green, Guan, Guan, Hackett, Hackett, Hackett, Hackett, Hamilton, He, He, He, Herrmann, Hollis, Hong, House, House, House, House, Hu, Hu, Huang, Huang, Hui, Hunt, Ji, Jia, Jiang, Jiang, Johnson, Johnson, Jongbloed, Jorge, Joubert, Juby, Katona, Katz, Keller, Kendall, Kimura, Kirsch, Kumar, Kwon, Lai, Lai, Laska, Latow, Lauritzen, Leff, Lehmann, Leijon, Li, Li, Li, Li, Li, Li, Li, Li, Li, Li, Liang, Liang, Lima, Lin, Lincoln, Lincoln, Lipsey, Lipsey, Liu, Liu, Liu, Liu, Liu, Lu, Mahoney, Mant, Mant, Martucci, Marui, McCusker, Meara, Meng, Miao, Min, Min, Mittmann, Miyai, Moher, Montgomery, Morris, Murray, Murray, Niedermaier, Niedermaier, Nir, Normand, Nour, Ohtomo, Ohtomo, Ostwald, Otomo, Parikh, Pearson, Ponzio, Rampello, Rampello, Rankin, Reding, Ricauda, Ricauda, Roberts, Robinson, Rodgers, Rudd, Ruddell, Rønning, Sandberg, Shan, Sharpe, Sinyor, Sivenius, Smedley, Smith, Snow, Song, Stenager, Su, Su, Sulch, Sulch, Suskin, Tan, Taragano, Taragano, Thomas, Towle, Towle, Towle, Turner-Stokes, Verhagen, Wade, Wade, Walker-Batson, Walsh, Wang, Wang, Wang, Wang, Ware, Watkins, Werner, Wheeler, Wiart, Wiart, Wilkinson, Williams, Wolfe, Wu, Xia, Xiaoying, Xie, Xie, Xie, Xing, Xu, Yang, Ye, Yi, Yoneyama, You, Young, Yu, Yu, Yu, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhao, Zhao, Zhou, Zhou B. Xiao, Zhu, Zifko, Zigmond, Zimmerman   +254 more
core   +1 more source