Results 1 to 10 of about 6,727 (271)

Citicoline May Effectively Reduce Hard Exudates in Diabetic Retinopathy [PDF]

Biomedicines
Background/Objectives: Diabetic retinopathy (DR) develops from the interplay of vascular, inflammatory, and neurodegenerative processes. Citicoline, a natural compound essential for cell membranes, enhances neurotransmitter levels, has a neuroprotective ...
Martina Tomić, Toma Babić, Tomislav Bulum, Spomenka Ljubić, Tomislav Jukić   +4 more
doaj   +4 more sources

The impact of citicoline on brain mitochondrial dysfunction induced in rats after head irradiation [PDF]

Scientific Reports
Head irradiation is a common treatment for brain cancer; however, it can cause side effects in healthy brain tissue. This study aimed to test whether citicoline administration modulates radiation-induced brain mitochondrial dysfunction in rats.
Nahed Abdel-Aziz, Fatma Rabia Algeda, Shereen M. Shedid   +2 more
doaj   +5 more sources

Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis [PDF]

Frontiers in Neurology
IntroductionSevere traumatic brain injury (sTBI) remains a major cause of long-term disability and mortality worldwide. Beyond the initial mechanical damage, a cascade of secondary injuries involving neuroinflammation, oxidative stress, and ...
Philipp Schlager, Philipp Schlager, Ivan Grgac, Ivan Grgac, Guenther Herzer, Guenther Herzer, Helmut Trimmel, Helmut Trimmel, Helmut Trimmel   +8 more
doaj   +5 more sources

The efficacy of different doses of citicoline in improving the prognosis of patients with acute ischemic stroke based on network meta-analysis [PDF]

Frontiers in Pharmacology
ObjectiveOur group aimed to explore the effect of different dosages of citicoline on ischemic stroke (IS) patients and determine the most appropriate dosage for these patients.MethodsThe databases of PubMed, Cochrane Library, Medline, Web of Science, and
Xu Zhao, Xianhao Huo, Yizhen Meng, Ran Zhao, Xiaozhuo Liu, Jiancheng Chen, Zhiqi Mao, Mei Li   +7 more
doaj   +3 more sources

Comparison of the effects of choline alphoscerate and citicoline in patients with dementia disorders: a systematic review and meta-analysis [PDF]

Frontiers in Neurology
BackgroundOver 44 million people worldwide live with dementia, affecting their quality of life and well-being. Choline alphoscerate and citicoline supplements are commonly used to improve cognitive function in dementia patients.
Getu Gamo Sagaro, Getu Gamo Sagaro, Francesco Amenta, Francesco Amenta   +3 more
doaj   +3 more sources

Neuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension [PDF]

Antioxidants
Glaucoma is a neurodegenerative disease characterized by the loss of retinal ganglion cells (RGCs), with intraocular pressure (IOP) being its primary risk factor. Despite controlling IOP, the neurodegenerative process often continues.
José A. Matamoros, Sara Rubio-Casado, José A. Fernández-Albarral, Miguel A. Martínez-López, Elena Salobrar-García, Eva M. Marco, Victor Paleo-García, Rosa de Hoz, Inés López-Cuenca, Lorena Elvira-Hurtado, Lidia Sánchez-Puebla, José M. Ramírez, Juan J. Salazar, Meritxell López-Gallardo, Ana I. Ramírez   +14 more
doaj   +3 more sources

‘Citicoline’ and support of the memory function: Evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 [PDF]

EFSA Journal
Following an application from Egde Pharma Sp. z o.o, submitted for authorisation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of Poland, the EFSA Panel on Nutrition, Novel Foods and Food ...
EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Androniki Naska, Kristina Pentieva, Frank Thies, Sophia Tsabouri, Marco Vinceti, Jean‐Louis Bresson, Thibault Fiolet, Alfonso Siani   +17 more
doaj   +3 more sources

Citicoline and Coenzyme Q10: Therapeutic Agents for Glial Activation Reduction in Ocular Hypertension. [PDF]

Pharmaceuticals (Basel)
Background/Objectives: The loss of retinal ganglion cells (RGCs) is a hallmark of glaucoma, a major cause of blindness. Glial cell activation due to increased intraocular pressure (IOP) significantly contributes to RGC death.
Matamoros JA, Rubio-Casado S, Fernández-Albarral JA, Martínez-López MA, Ramírez AI, Salobrar-García E, Marco EM, Paleo-García V, de Hoz R, López-Cuenca I, Elvira-Hurtado L, Sánchez-Puebla L, Ramírez JM, López-Gallardo M, Salazar JJ.   +14 more
europepmc   +2 more sources

Citicoline Oral Solution Induces Functional Enhancement and Synaptic Plasticity in Patients with Open-Angle Glaucoma. [PDF]

J Clin Med
Objectives: To evaluate the changes in retinal function and neural conduction along the visual pathways after 12 months of treatment with Citicoline oral solution in patients with open-angle glaucoma (OAG).
Parisi V, Ziccardi L, Tanga L, Barbano L, Tinelli E, Coppola G, Di Renzo A, Michelessi M, Roberti G, Carnevale C, Giammaria S, Dell'Aquila C, D'Andrea M, Manni G, Oddone F.   +14 more
europepmc   +2 more sources

Impact of Oral Citicoline, Antioxidant Vitamins, and Blackcurrant Supplementation on Primary Open-Angle Glaucoma: An OCT and OCTA Study. [PDF]

Biomedicines
Purpose: We sought to evaluate the long-term effects of oral citicoline; vitamins A, B, C, and E; and blackcurrant therapy in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT), OCT angiography (OCTA), and ...
Giunta P, D'Andrea L, Rinaldi M, Laezza MP, Piscopo R, Costagliola C.   +5 more
europepmc   +2 more sources