Results 31 to 40 of about 6,727 (271)

Citicoline for traumatic brain injuries: A systematic review and implications for future research

open access: yesArchives of Trauma Research, 2022
Background and Objectives: Traumatic brain injury (TBI) is a catastrophic condition that exerts a high burden on individuals, families, and societies. The objective of this study was to systematically review the human studies on the efficacy and safety ...
Moein Khormali   +4 more
doaj   +1 more source

The Effect of Oral Citicoline and Docosahexaenoic Acid on the Visual Field of Patients with Glaucoma: A Randomized Trial

open access: yesLife, 2022
The role of nutraceuticals in the treatment of glaucoma remains controversial. The aim of this study was to evaluate the effect of citicoline, vitamin C, and docosahexaenoic acid (DHA) in patients with glaucoma.
Alfonso Anton   +6 more
doaj   +1 more source

Posible involvement of nitric oxide in anticonvulsant effects of citicoline on pentylenetetrazole and electroshock induced seizures in mice

open access: yesHeliyon, 2020
Cerebroneurovascular trauma is recognized as an important risk factor in the development of seizure and epilepsy. Administration of citicoline in these situations is a conventional therapeutic strategy, which combines neurovascular protection and repair ...
Rokhsana Rasooli   +2 more
doaj   +1 more source

Pharmacotherapy for Poststroke Cognitive Impairment and Poststroke Cognitive Impairment With Dementia: A Review. [PDF]

open access: yesStroke Res Treat
Poststroke cognitive impairment (PSCI) refers to any level of cognitive decline occurring after a stroke, ranging from mild to severe impairments, while PSCI with dementia describes a more severe form where the cognitive decline significantly affects daily functioning and meets the clinical criteria for dementia.
Ravi R   +4 more
europepmc   +2 more sources

Citicoline in Ophthalmological Neurodegenerative Disease: A Comprehensive Review [PDF]

open access: yesPharmaceuticals, 2021
Cytidine 5’-diphosphocholine has been widely studied in systemic neurodegenerative diseases, like Alzheimer’s disease, Parkinson’s disease, and brain ischemia. The rationale for the use of citicoline in ophthalmological neurodegenerative diseases, including glaucoma, anterior ischemic optic neuropathy, and diabetic retinopathy, is founded on its ...
Francesco Oddone   +10 more
openaire   +4 more sources

Citicoline: neuroprotective mechanisms 
in cerebral ischemia [PDF]

open access: yesJournal of Neurochemistry, 2001
AbstractCytidine‐5′‐diphosphocholine (citicoline or CDP‐choline), an intermediate in the biosynthesis of phosphatidylcholine (PtdCho), has shown beneficial effects in a number of CNS injury models and pathological conditions of the brain. Citicoline improved the outcome in several phase‐III clinical trials of stroke, but provided inconclusive results ...
Rao Muralikrishna, Adibhatla   +2 more
openaire   +2 more sources

Role of Citicoline in Patients With Mild Cognitive Impairment

open access: yesNeuroscience Insights, 2023
The term mild cognitive impairment (MCI) defines an intermediate state between normal aging and dementia. Vascular cognitive impairment refers to a decline in cognitive function that is caused by or associated with vascular disease and comprises all the ...
Pedro E Bermejo   +2 more
doaj   +1 more source

Citicoline for Supporting Memory in Aging Humans

open access: yesAging and disease, 2022
Citicoline is the generic name of CDP-choline, a natural metabolite presents in all living cells. Used in medicine as a drug since the 1980-s, citicoline was recently pronounced a food ingredient. When ingested, citicoline breaks down to cytidine and choline, which become incorporated into their respective normal metabolic pathways.
Świątkiewicz, Maciej, Grieb, Paweł
openaire   +2 more sources

New advances in amblyopia therapy I: Binocular therapies and pharmacologic augmentation [PDF]

open access: yes, 2018
Amblyopia therapy options have traditionally been limited to penalisation of the non-amblyopic eye with either patching or pharmaceutical penalisation. Solid evidence, mostly from the Pediatric Eye Disease Investigator Group, has validated both number of
Culican, Susan M, Kraus, Courtney L
core   +2 more sources

Duration of Posttraumatic Amnesia Predicts Neuropsychological and Global Outcome in Complicated Mild Traumatic Brain Injury. [PDF]

open access: yes, 2016
OBJECTIVES: Examine the effects of posttraumatic amnesia (PTA) duration on neuropsychological and global recovery from 1 to 6 months after complicated mild traumatic brain injury (cmTBI). PARTICIPANTS: A total of 330 persons with cmTBI defined as Glasgow
Barber, Jason   +10 more
core   +2 more sources

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