Results 41 to 50 of about 6,727 (271)
Neurobiology of Disease, 2005 Background and purpose:: Cytidine-5′-diphosphocholine (citicoline or CDP-choline), an intermediate in the biosynthesis of phosphatidylcholine, has shown beneficial effects in a number of CNS injury models including cerebral ischemia.
Olivia Hurtado +11 more
doaj +1 more source
[The role of citicoline in glaucoma]. [PDF]
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2021 In recent years, many experimental and clinical studies have shown that in glaucoma, neuronal degeneration occurs not only at the level of the retina and optic nerve, but also along the entire visual pathway and the brain.This article presents the neuroprotective effects of citicoline and their mechanisms in glaucoma disease.The relevance of citicoline
Anselm G M, Jünemann +2 more
openaire +3 more sources
Citicoline Preclinical and Clinical Update 2009–2010 [PDF]
Stroke, 2011 Citicoline is a neuroprotectant and neurorestorative drug that is used in the treatment of acute ischemic stroke in some countries. The research with this compound continues. In this review, we focus on the latest publications or communications or both and on the major ongoing experimental and clinical projects involving citicoline in stroke recovery.
Davalos, A, Secades, J
openaire +3 more sources
Patologìâ, 2021 The aim of this study was to investigate the clinical and biochemical efficiency of citicoline in cognitive improvement and changes of glutathione peroxidase (GPx) blood plasma levels in patients at early stages of Parkinson’s disease (PD).
A. V. Demchenko, V. V. Biriuk
doaj +1 more source
Serum Hsp70 antigen: Early diagnosis marker in perinatal asphyxia [PDF]
, 2015 BACKGROUND: Perinatal asphyxia is an important cause of mortality and permanent neurological and developmental deficit. Early and accurate diagnosis would help to establish the likely prognosis and may also help in determining the most appropriate ...
Boskabadi, Hassan +6 more
core +1 more source
Synthesis of Process Related Impurities of Citicoline and Citicoline Sodium
Indian Journal of ChemistryNilesh Bonde +3 more
openalex +3 more sources
Journal of Pharmacological Sciences, 2019 Phospholipids are structural components of cellular membranes that play important roles as precursors for various signaling pathways in modulating neuronal membrane function and maintenance of the intracellular environment.
Eri Nakazaki +7 more
doaj +1 more source
Assessment of visual contrast function and effects of citicoline treatment in children with visual impairment [PDF]
, 2014 Purpose: The present studies address the questions if visual dysfunction in severely visually impaired children can be measured with contrast tests high or low, how it relates to their visual abilities assessed with behavioural methods and if visual ...
Siddiqui, Aamir
core +1 more source
Liposomal Encapsulation of Citicoline for Ocular Drug Delivery
International Journal of Molecular Sciences, 2023 Glaucoma represents a group of neurodegenerative diseases characterized by optic nerve damage and the slowly progressive death of retinal ganglion cells. Glaucoma is considered the second leading cause of irreversible blindness worldwide. Pharmaceutical treatment of glaucoma is critical because of the properties of the ocular barrier that limit the ...
Bonechi, Claudia +8 more
openaire +4 more sources
Pharmaceuticals, 2022 Extracellular vesicles are recognized as signaling mediators between cells both in physiological and pathological communication. In this work, we explored the potential effect of citicoline to modify relevant proteins or miRNAs for cardioprotection in ...
Alejandro Silva-Palacios +11 more
doaj +1 more source