Results 11 to 20 of about 346,140 (362)

Changes in TCA cycle and TCA cycle-related metabolites in plasma upon citric acid administration in rats

open access: yesHeliyon, 2021
Recent studies have reported that plasma levels of tricarboxylic acid (TCA) cycle metabolites and TCA cycle-related metabolite change in patients with chronic fatigue syndrome (CFS) and in healthy humans after exercise.
Yurie Hara   +3 more
doaj   +2 more sources

FaGAPC2/FaPKc2.2 and FaPEPCK reveal differential citric acid metabolism regulation in late development of strawberry fruit

open access: yesFrontiers in Plant Science, 2023
Citric acid is the primary organic acid that affects the taste of strawberry fruit. Glycolysis supplies key substrates for the tricarboxylic acid cycle (TCA cycle).
Min Yang   +18 more
doaj   +2 more sources

Citric Acid Production by Aspergillus niger Using Solid-State Fermentation of Agricultural Processing Coproducts

open access: yesApplied Biosciences, 2023
The ability of Aspergillus niger strains to support citric acid production using solid-state fermentation of agricultural processing coproducts was examined in this review.
Thomas P. West
doaj   +2 more sources

Citric Acid Cycle Intermediates in Cardioprotection [PDF]

open access: yesCirculation: Cardiovascular Genetics, 2014
Over the last decade, there has been a concerted clinical effort to deliver on the laboratory promise that a variety of maneuvers can profoundly increase cardiac tolerance to ischemia and/or reduce additional damage consequent upon reperfusion. Here we will review the proximity of the metabolic approach to clinical practice. Specifically, we will focus
Czibik, G   +3 more
openaire   +5 more sources

Citric Acid Production of Yeasts: An Overview

open access: yesThe EuroBiotech Journal, 2021
Citric acid, an intermediate product of the Krebs cycle, has a wide usage area in the food industry since it has some functions such as acidulant, flavouring agent, preservative and antioxidant. Although molds are the most commonly used microorganisms in
Börekçi Bilge Sayın   +2 more
doaj   +2 more sources

Citric acid promoted melanin synthesis in B16F10 mouse melanoma cells, but inhibited it in human epidermal melanocytes and HMV-II melanoma cells via the GSK3β/β-catenin signaling pathway.

open access: yesPLoS ONE, 2020
Melanin, a pigment synthesized by melanocytes in the skin, resists the damage caused by ultraviolet rays to cells. Citric acid, a well-known food additive, is commonly used as an antioxidant and is an important part of the tricarboxylic acid (TCA) cycle ...
Siqi Zhou, Kazuichi Sakamoto
doaj   +2 more sources

Rethinking the Citric Acid Cycle: Connecting Pyruvate Carboxylase and Citrate Synthase to the Flow of Energy and Material. [PDF]

open access: yesInt J Mol Sci, 2021
In 1937, Sir H. A Krebs first published the Citric Acid Cycle, a unidirectional cycle with carboxylic acids. The original concept of the Citric Acid Cycle from Krebs’ 1953 Nobel Prize lecture illustrates the unidirectional degradation of lactic acid to ...
Roosterman D, Cottrell GS.
europepmc   +2 more sources

Effect of Citric Acid Cycle Genetic Variants and Their Interactions with Obesity, Physical Activity and Energy Intake on the Risk of Colorectal Cancer: Results from a Nested Case-Control Study in the UK Biobank. [PDF]

open access: yesCancers (Basel), 2020
Simple Summary The citric acid cycle has a central role in the cellular energy metabolism and biosynthesis of macromolecules in the mitochondrial matrix.
Cho S, Song N, Choi JY, Shin A.
europepmc   +2 more sources

A citric acid cycle-deficient Escherichia coli as an efficient chassis for aerobic fermentations. [PDF]

open access: yesNat Commun
Tricarboxylic acid cycle (TCA cycle) plays an important role for aerobic growth of heterotrophic bacteria. Theoretically, eliminating TCA cycle would decrease carbon dissipation and facilitate chemicals biosynthesis. Here, we construct an E.
Zhou H   +8 more
europepmc   +2 more sources

Regulation of leukocyte function by citric acid cycle intermediates. [PDF]

open access: yesJ Leukoc Biol, 2019
Cellular metabolism is a means of generating ATP to provide energy for key cellular functions. However, recent research shows that citric acid cycle intermediates target vital cellular functions of the innate immune system. Succinate, itaconate, citrate,
Patil NK   +4 more
europepmc   +2 more sources

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