Results 21 to 30 of about 346,140 (362)

Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells. [PDF]

Nat Metab, 2019
Clerc I, Moussa DA, Vahlas Z, Tardito S, Oburoglu L, Hope TJ, Sitbon M, Dardalhon V, Mongellaz C, Taylor N.   +9 more
europepmc   +2 more sources

Thermodynamic Constraints on the Citric Acid Cycle and Related Reactions in Ocean World Interiors. [PDF]

ACS Earth Space Chem
Işık S, Melwani Daswani M, Işık E, Weber JM, Olgun Kıyak N.   +4 more
europepmc   +2 more sources

Low-dose cadmium disrupts mitochondrial citric acid cycle and lipid metabolism in mouse lung. [PDF]

Free Radic Biol Med, 2019
Hu X, Chandler JD, Park S, Liu K, Fernandes J, Orr M, Smith MR, Ma C, Kang SM, Uppal K, Jones DP, Go YM.   +11 more
europepmc   +2 more sources

Glutamate-oxaloacetate transaminase activity promotes palmitate lipotoxicity in rat hepatocytes by enhancing anaplerosis and citric acid cycle flux. [PDF]

J Biol Chem, 2019
Hepatocyte lipotoxicity is characterized by aberrant mitochondrial metabolism, which predisposes cells to oxidative stress and apoptosis. Previously, we reported that translocation of calcium from the endoplasmic reticulum to mitochondria of palmitate ...
Egnatchik RA, Leamy AK, Sacco SA, Cheah YE, Shiota M, Young JD.   +5 more
europepmc   +2 more sources

Efficacy and Engagement With an Immersive Virtual Learning Experience of the Citric Acid Cycle. [PDF]

Biochem Mol Biol Educ
Braga BC, Hurst W, Barrow J, Long J, Shearer GC, Hodges JK, Lawler O, Patel R, Schiavone T, Masterson TD.   +9 more
europepmc   +2 more sources

Lipotoxic Palmitate Impairs the Rate of β-Oxidation and Citric Acid Cycle Flux in Rat Neonatal Cardiomyocytes [PDF]

Cellular Physiology and Biochemistry, 2016
Background/Aims: Diabetic hearts exhibit intracellular lipid accumulation. This suggests that the degree of fatty acid oxidation (FAO) in these hearts is insufficient to handle the elevated lipid uptake.
Taha Haffar, Ali Akoumi, Nicolas Bousette   +2 more
openalex   +2 more sources

A study of the citric acid cycle in certain tumour tissue [PDF]

Biochemical Journal, 1961
R.M. Dajani, J. Danielski, W. Gamble, JM ORTEN   +3 more
openalex   +5 more sources

Citric Acid in Endodontics: A Review [PDF]

Journal of Dental Materials and Techniques, 2021
Naturally occurring in citrus fruits, citric acid is categorized as a weak organic acid, which may exist both as a monohydrate or in an anhydrous form.
Zahed Mohammadi, Jun-Ichiro Kinoshita, Sousan Shalavi, Aghaghia Mokhber, Hamid Jafarzadeh   +4 more
doaj   +1 more source

Abiotic origin of the citric acid cycle intermediates

Proceedings of the National Academy of Sciences
The molecular framework for protometabolism—chemical reactions in a prebiotic environment preceding modern metabolism—has remained unknown in evolutionary biology. Mono-, di-, and tricarboxylic acids that comprise contemporary metabolism, such as the Krebs cycle, are of particular prebiotic relevance and are theorized to predate life on Earth ...
Mason McAnally, Jana Bocková, Andrew M. Turner, Norimasa Hara, Daria Mikhnova, Cornelia Meinert, Cheng Zhu   +6 more
openalex   +3 more sources

Alternative reactions at the interface of glycolysis and citric acid cycle in Saccharomyces cerevisiae. [PDF]

FEMS Yeast Res, 2016
Pyruvate and acetyl-coenzyme A, located at the interface between glycolysis and TCA cycle, are important intermediates in yeast metabolism and key precursors for industrially relevant products.
van Rossum HM, Kozak BU, Niemeijer MS, Duine HJ, Luttik MA, Boer VM, Kötter P, Daran JM, van Maris AJ, Pronk JT.   +9 more
europepmc   +2 more sources