Results 71 to 80 of about 3,828 (143)

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

DNA From Neutrophil Extracellular Traps Restricts Group 3 Innate Lymphoid Cells Function in Intestinal Epithelial Repair via CCDC25

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
DNA from neutrophil extracellular traps (NET‐DNA) restricts the function of IL‐22‐dependent ILC3s in intestinal defense through coiled‐coil domain containing protein 25 (CCDC25), which hinders the repair of intestinal epithelial cells and promotes the progression of UC.
Bo Xu, Xuezhou Ke, Xueqian Xie, Qi Yi, Chunjing Li, Meng Zhao, Xiangliang Deng, Qing Wang, Hongxu Chen, Rui Xu, Shuiling Cao, Ying Zhu, Lian Zhou, Qimei Wang, Xia Luo   +14 more
wiley   +1 more source

Case report: In vivo detection of neutrophil extracellular traps in a dog with thrombosis induced by bacterial vasculitis

Frontiers in Veterinary Science
This case report describes NETosis as a cause of thrombosis in an 18.3 kg, 8-year-old intact male mixed-breed dog with bacterial vasculitis. The dog presented with sudden paresis of the thoracic limb, characterized by cyanosis, absent arterial pulse, and
Ju-Yun Kim, Hyun-Jung Han
doaj   +1 more source

Complement–Eosinophil Crosstalk Links Complement Activation to Fibrin Deposition in Eosinophilic Chronic Rhinosinusitis

Allergy, EarlyView.
Ryo Hasegawa, Shigeharu Ueki, Misaki Arima, Shohei Nishiyama, Keinosuke Hizuka, Kohei Tatsumi, Ayako Sawai, Anna Shimizu, Yuki Sonoda, Eiichi Kato, Masanori Kidoguchi, Masafumi Sakashita, Yohei Sato, Atsushi Kato, Bruce K. Tan, Robert C. Kern, Robert P. Schleimer, Shigeharu Fujieda, Yoshimasa Imoto   +18 more
wiley   +1 more source

Longitudinal dynamics of hemostatic biomarkers in patients with cancer receiving immune checkpoint inhibitors vs chemotherapy: results from the Vienna CAT-BLED study

Research and Practice in Thrombosis and Haemostasis
Background: Venous thromboembolism is a common cause of morbidity and mortality in patients with cancer, with chemotherapy being an established risk factor.
Nikola Vladic, Cornelia Englisch, Julia Maria Berger, Florian Moik, Hubert Hayden, Johannes Thaler, Anna Sophie Berghoff, Thorsten Fuereder, Matthias Preusser, Ingrid Pabinger, Cihan Ay   +10 more
doaj   +1 more source

The chronicles of inflammation: uncovering of distinct patterns of NET degradation products

Frontiers in Drug Discovery
AimsNeutrophils and neutrophil extracellular traps (NETs) play multifaceted roles in inflammatory diseases. If the balance of NET formation and clearance is disturbed, they contribute to the development and pathogenesis of a plethora of inflammatory ...
Janina Schoen, Janina Schoen, Marco Muñoz-Becerra, Marco Muñoz-Becerra, Jasmin Knopf, Favour Ndukwe, Favour Ndukwe, Moritz Leppkes, Moritz Leppkes, Dominik Roth, Anne Zeitler, Anne Zeitler, Verena Gerlinde Frings, Bettina Hohberger, Victoria Zeisberg, Luis E. Muñoz, Luis E. Muñoz, Georg Schett, Georg Schett, Martin Herrmann, Martin Herrmann, Martin Herrmann, Christine Schauer, Christine Schauer   +23 more
doaj   +1 more source

Neutrophil extracellular traps as biomarkers for predicting prognosis and chemotherapy response in colorectal cancer

Scientific Reports
Colorectal cancer (CRC) is a prevalent malignancy with high mortality. Neutrophil extracellular traps (NETs) are implicated in metastasis and chemotherapy resistance, making them potential biomarkers for prognosis and treatment response.
Chen Wang, Junxiong Chen, Ziyin Song, Kexin Lv, Haiyan Dong, Liumei Liang, Jingdan Zhang, Huanliang Liu, Jianxia Li, Xiangling Yang   +9 more
doaj   +1 more source

Recombinant thrombomodulin and recombinant antithrombin attenuate pulmonary endothelial glycocalyx degradation and neutrophil extracellular trap formation in ventilator-induced lung injury in the context of endotoxemia

Respiratory Research
Background Vascular endothelial damage is involved in the development and exacerbation of ventilator-induced lung injury (VILI). Pulmonary endothelial glycocalyx and neutrophil extracellular traps (NETs) are endothelial protective and damaging factors ...
Kenichiro Kikuchi, Satoshi Kazuma, Michiaki Yamakage   +2 more
doaj   +1 more source

Correction: Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer. [PDF]

J Exp Clin Cancer Res, 2023
Ronchetti L, Terrenato I, Ferretti M, Corrado G, Goeman F, Donzelli S, Mandoj C, Merola R, Zampa A, Carosi M, Blandino G, Conti L, Lobascio AM, Iacobelli M, Vizza E, Piaggio G, Gurtner A.   +16 more
europepmc   +1 more source

Elevated levels of neutrophil related chemokine citrullinated histone H3, interleukin-8 and C-reaction protein in patients with immune checkpoint inhibitor therapy: predictive biomarkers for response to treatment. [PDF]

Cancer Cell Int, 2023
Wang X, Huang H, Zhang L, Wu Y, Wen Y, Weng X, Chen Q, Liu W.   +7 more
europepmc   +1 more source