Results 81 to 90 of about 3,828 (143)

Biomarkers in endotoxemia with a special interest in citrullinated histone H3

, 2018
Background: Sepsis with multi-organ failure has an unacceptably high mortality rate of 25-30% despite the use of antibiotics and modern intensive care. Attenuating the multi-organ failure and finding new biomarkers for early detection of septic shock would be of high clinical relevance in order to improve outcome.
openaire   +1 more source

Moxibustion-mediated alleviation of synovitis in rats with rheumatoid arthritis through the regulation of NLRP3 inflammasome by modulating neutrophil extracellular traps

Heliyon
Purpose: This study investigates the potential mechanism of moxibustion in the treatment of rheumatoid arthritis (RA) by regulating the neutrophil extracellular trap (NET)/NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome ...
Miao Wang, Hongfang Zhao, Hui Zhao, Chenlu Huo, Yu Yuan, Yan Zhu   +5 more
doaj   +1 more source

The effect of chemical fixation with paraformaldehyde, glutardialdehyde or methanol on immunofluorescence staining of neutrophils and neutrophil extracellular traps

Innate Immunity
The formation of neutrophil extracellular traps (NETs) is known as an important part of the innate immune response. Still, some mechanisms regarding their formation and role during a disease are not completely understood yet.
Veronika Pilchová, Armina Richter, Marita Meurer, Claudia Schulz, Maren von Köckritz-Blickwede   +4 more
doaj   +1 more source

Serum citrullinated histone H3 concentrations differentiate patients with septic verses non-septic shock and correlate with disease severity. [PDF]

Infection, 2021
Tian Y, Russo RM, Li Y, Karmakar M, Liu B, Puskarich MA, Jones AE, Stringer KA, Standiford TJ, Alam HB.   +9 more
europepmc   +1 more source

From Inflammation to Bone Loss: The Multifaceted Role of Neutrophils in Osteoporosis

International Journal of Inflammation
Neutrophils, the most abundant innate immune cells, have recently emerged as central regulators in the pathogenesis and treatment of osteoporosis. Traditionally viewed as transient inflammatory responders, neutrophils are now recognized as dynamic ...
Hao Cheng, Yipeng Cheng, Guodong Wang, Decheng Wang, Ximing Liu   +4 more
doaj   +1 more source

Evaluation of NETosis (Neutrophil Extracellular Traps) biomarkers in smokers and nonsmokers periodontitis patients [version 2; peer review: 1 approved, 3 approved with reservations, 2 not approved]

F1000Research
Background To evaluate the NETosis biomarkers citrullinated histone H3 (citH3), neutrophil elastase (ELA), calprotectin (CALPRO), and myeloperoxidase (MPO) as indicators of inflammation in the severe stages of periodontitis III and IV in both (smokers ...
Batool Hassan Al Ghurabi, Rasha Abdul Jabbar Najim   +1 more
doaj   +1 more source

Quantification of Citrullinated Histone H3 as a Marker for Neutrophil Extracellular Traps Correlated to Clinical Characteristics of Patients with Systemic Lupus Erythematosus

Archivum Immunologiae et Therapiae Experimentalis
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disease whose pathogenesis is not fully understood to date. One of the suggested mechanisms for its development is NETosis, which involves the release of a specific network consisting of chromatin, proteins, and enzymes from neutrophils, stimulating the ...
Maciej, Dubaj, Iwona, Homa-Mlak, Aleksandra, Majdan, Radosław, Mlak, Maria, Majdan, Teresa, Małecka-Massalska   +5 more
openaire   +2 more sources

Bone marrow aspirate Cit-H3 was identified as a novel biomarker of minimal residual disease in neuroblastoma

BMC Cancer
Background Neuroblastoma (NB) is the most prevalent extracranial solid tumor in children. Neutrophils release neutrophil extracellular traps (NETs) following intense or prolonged activation. Neutrophil elastase (ELA2) and citrullinated histone H3 (Cit-H3)
Mengxia Zhang, Xiang Wang, Lin Liu, Yuge Ni, Yuanyuan Zhang, Xiaoyan Hu, Chen Huang, Baocheng Gong, Tiantian She, Chong Chen   +9 more
doaj   +1 more source

249 Rheumatoid arthritis neutrophil extra-cellular traps contain citrullinated histone-H3 [PDF]

Rheumatology, 2018
Max A Lyon, Elinor A Chapman, Robert J Moots, Helen L Wright   +3 more
openaire   +1 more source

Serum citrullinated histone H3 as a biomarker of disease activity and renal outcome in microscopic polyangiitis and granulomatosis with polyangiitis. [PDF]

Arthritis Res Ther
Kwon OC, Yoon T, Ha JW, Park YB, Lee SW.
europepmc   +1 more source