Results 211 to 220 of about 12,205 (240)
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Citrulline and anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis
Future Rheumatology, 2006Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by the destruction of multiple joints along with multiple organ involvement. The etiology of RA is still unknown. Various autoantigens have been proposed as targets of pathogenic T and B cells in RA, although none of their precise mechanisms or significance has been confirmed ...
Ryo Yamada +2 more
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Cyclic Citrullinated Peptide Aptamer Treatment Attenuates Collagen-Induced Arthritis
Biomacromolecules, 2022We describe the study of a novel aptamer-based candidate for treatment of seropositive rheumatoid arthritis. The candidate is a nanoparticle-formulated cyclic citrullinated peptide aptamer, which targets autoantibodies and/or the immune reactions leading to antibody production.
Sangita Khatri +12 more
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Anti-cyclic citrullinated peptide antibodies in scleroderma patients
Clinical Rheumatology, 2012Anti-CCP (cyclic citrullinated peptide) is considered the most useful laboratory tool in the diagnosis of rheumatoid arthritis (RA). Some authors have also found this autoantibody in patients with scleroderma (SSc). The study aimed to investigate the prevalence of anti-CCP antibodies in SSc patients from Southern Brazil and their association with ...
M, Polimeni +3 more
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Citrullinated Peptides in the Diagnosis of Rheumatoid Arthritis
Current Topics in Medicinal Chemistry, 2013Antibodies directed against citrullinated proteins and peptides (ACPAs) are the most specific serological markers available for diagnosing rheumatoid arthritis (RA). ACPAs may be detected several years before symptoms of RA appear, and their presence at disease onset is a good predictor of the development of erosive joint lesions.
María J, Gómara, Isabel, Haro
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Specific biotinylation and sensitive enrichment of citrullinated peptides
Analytical and Bioanalytical Chemistry, 2013Protein citrullination is a posttranslational modification where peptidylarginine is enzymatically deiminated to form peptidylcitrulline. Although the role of protein citrullination in both health and disease is being increasingly recognised, techniques available to identify citrullinated proteins and to map their citrullination site(s) are rare and ...
Astrid E V, Tutturen +2 more
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Anticyclic citrullinated peptide autoantibodies in systemic lupus erythematosus
Rheumatology International, 2010Systemic lupus erythematosus is an autoimmune disease with protean manifestation. Arthritis is one of the most common manifestations seen in SLE. Anti-CCP Ab is a recently described autoantibody that has been claimed as a most sensitive and specific marker for the diagnosis of RA.
Usha, Singh +4 more
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Anticyclic citrullinated peptide antibodies in juvenile idiopathic arthritis
Modern Rheumatology, 2006Anticyclic citrullinated peptide (anti-CCP) antibodies have been detected in patients with juvenile idiopathic arthritis (JRA), particularly in those with polyarticular JIA. We analyzed the presence of anti-CCP antibodies of the IgG class in sera of patients with defined juvenile idiopathic arthritis (JIA) of various subgroups.
Jürgen K H, Brunner +1 more
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Application of synthetic peptides for detection of anti-citrullinated peptide antibodies
Peptides, 2016Anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA) and represent an important tool for the serological diagnosis of RA. In this study, we describe ACPA reactivity to overlapping citrullinated Epstein-Barr virus nuclear antigen-1 (EBNA-1)-derived peptides and analyze their potential as substrates for ACPA detection
Trier, Nicole Hartwig +9 more
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Anti -citrullinated peptide antibodies profiling in established rheumatoid arthritis
Joint Bone Spine, 2018Anti-citrullinated protein/peptide antibodies (ACPA) represent an important tool for the diagnosis of rheumatoid arthritis (RA) and the presence of multiple ACPA specificities is highly correlated with the evolution towards RA. However, little is known about the association of single specificities with disease manifestations and response to therapy in ...
MANCA, MARIA LAURA +7 more
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Anti-Cyclic Citrullinated Peptide antibodies
Revue Tunisienne de BIOLOGIE CLINIQUE, Vol. 31 No 2 (2024): Edition spéciale : «Auto-anticorps : le mystère révélé»Fenniche, Insaf, Gereisha, Ahmed Adel
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