Results 141 to 150 of about 37,088 (271)
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet +6 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman +10 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT In an infant with cholestasis and recurrent hypoglycemia, the combination of hypercitrullinemia, hypermethioninemia, and hyperthreoninemia should prompt testing for citrin deficiency, because early metabolic and genetic diagnosis allows targeted nutritional treatment and rapid clinical improvement.
Julien Neveu +4 more
wiley +1 more source
Molecular Carcinogenesis, Volume 65, Issue 10, Page 1281-1296, October 2026.ABSTRACT Neutrophil extracellular traps (NETs) play crucial roles in cancer progression, but their regulatory mechanisms in breast cancer remain poorly understood. We developed a NETs‐related prognostic risk model using TCGA breast cancer data and identified key biomarkers through bioinformatics analysis.
Zhen Huang +9 more
wiley +1 more source
Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease
MedComm, Volume 7, Issue 10, October 2026.NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang +9 more
wiley +1 more source
Effects of citrulline nutritional therapy in elective surgery patients
, 2016 Citrulline은 특별한 대사를 통하여 요소회로와 NO생성에서 중요한 역할을 한다. 최근 arginine의 전구체로써 뿐만 아니라 항산화효과, 심혈관계에서의 역할, 면역조절, 질소항상성 조절의 역할 등 citrulline에 대한 연구가 급증하였다. 그러나 아직 ASPEN, ESPEN, Canadian guidelines 에서도 구체적인 언급이 없고 임상적 적용을 위해서는 추가적인 연구가 필요하다.
양진아
core +1 more source
Harnessing Quantitative Medicine to Advance Oncology Drug Development
Clinical and Translational Science, Volume 19, Issue 10, October 2026.ABSTRACT Oncology drug development continues to have a high attrition rate despite major advances in therapeutic modalities such as antibody‐drug conjugates, bispecific antibodies, cell therapies, and cancer vaccines. Critical development decisions are often made under substantial uncertainty, creating a need for quantitative approaches that integrate ...
Benjamin Wu +3 more
wiley +1 more source