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Citrus Flavonoids and the Prevention of Atherosclerosis
Cardiovascular & Hematological Disorders-Drug Targets, 2012Epidemiological studies have demonstrated that diets rich in fruits and vegetables can prevent or delay the onset of many chronic diseases including cardiovascular disease (CVD). While more current research has begun to focus on the effects of specific polyphenol compounds found in fruits and vegetables, mechanistic insights have been hampered by the ...
Erin E, Mulvihill, Murray W, Huff
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Tetrahedron, 1963
Abstract The flavonols limocitrol and isolimocitrol, isolated from Citrus limon , are shown to be 3,5,7,4′-tetrahydroxy-6,8,3′-trimethoxyflavone and 3,5,7,3′-tetrahydroxy-6,8,4′-trimethoxyflavone, respectively. Each occurs as a 3-β- d -glucoside, as does the previously described flavonol, limocitrin (3,5,7,4′-tetrahydroxy-8,3′-dimethoxyflavone).
B. Gentili, R.M. Horowitz
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Abstract The flavonols limocitrol and isolimocitrol, isolated from Citrus limon , are shown to be 3,5,7,4′-tetrahydroxy-6,8,3′-trimethoxyflavone and 3,5,7,3′-tetrahydroxy-6,8,4′-trimethoxyflavone, respectively. Each occurs as a 3-β- d -glucoside, as does the previously described flavonol, limocitrin (3,5,7,4′-tetrahydroxy-8,3′-dimethoxyflavone).
B. Gentili, R.M. Horowitz
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Citrus flavonoids and lipid metabolism
Current Opinion in Lipidology, 2013Citrus flavonoids are polyphenolic compounds with powerful biological properties. This review aims to summarize recent advances towards understanding the ability of citrus flavonoids to regulate lipid metabolism and other metabolic parameters relevant to the metabolic syndrome, type 2 diabetes and cardiovascular disease.Citrus flavonoids, including ...
Julia M, Assini +2 more
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Biosynthesis of citrus flavonoids and their health effects
Critical Reviews in Food Science and Nutrition, 2018Citrus-derived flavonoids play important roles in the regulation of physiological conditions of citrus plants, including color changes of flower and fruit, flavor development, and anti-stress physiology. Moreover, citrus flavonoids possess multiple health-promoting effects in humans, and they are important ingredients for nutraceuticals and functional ...
Chengying Zhao +4 more
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The use of citrus flavonoids in infections. II
The American Journal of Digestive Diseases, 1955In 69 cases of acute respiratory infections (of which23 have previously been reported), including the common cold, acute follicular tonsillitis and influenza, oral therapy with the whole water soluble citrus flavonoid complex (vitamin “P” complex) led to rapid subsidence of the infection usually in from 8 to 48 hours, occasionally somewhat longer ...
M S, BISKIND, W C, MARTIN
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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis
Annual Review of Nutrition, 2016Citrus flavonoids are polyphenolic compounds with significant biological properties. This review summarizes recent advances in understanding the ability of citrus flavonoids to modulate lipid metabolism, other metabolic parameters related to the metabolic syndrome, and atherosclerosis.
Erin E Mulvihill +2 more
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Inhibition of Oral Carcinogenesis by Citrus Flavonoids
Nutrition and Cancer, 2007Six citrus flavonoids were tested for antineoplastic activity. The hamster cheek pouch model was utilized, and the solutions of the flavonoids (2.0-2.5%) and the solution of the carcinogen, 7,12-dimethylbenz[a]anthracene (0.5%), were applied topically to the pouches.
Edward G, Miller +6 more
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Citrus flavonoids as potential therapeutic agents: A review
Phytotherapy Research, 2021The plants Rutaceae family are known to have contributed a lot toward food and medicine. The most important metabolites of the family are flavonoids. A systematic review was conducted to collect chemical and pharmacological information of flavonoids isolated from family Rutaceae till 2018.
Fiaz Alam +4 more
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Inhibition of Bacterial Mutagenesis byCitrusFlavonoids
Planta Medica, 1996The antimutagenicity of the Citrus flavonoids naringin, hesperidin, nobiletin, and tangeretin against the mutagens benzo[a]pyrene, 2-aminofluorene, quercetin, and nitroquinoline N-oxide was investigated in the Salmonella/microsome assay. Naringin and hesperidin showed a weak antimutagenic activity against benzo[a]pyrene.
Calomme, M. +3 more
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Inhibition of Mammary Cancer by Citrus Flavonoids
1998Double strength orange juice given to the rats in place of drinking water inhibited mammary tumorigenesis induced in female Sprague-Dawley rats by DMBA more effectively than double strength grapefruit juice. This may mean that hesperetin retains its effectiveness in vivo better than naringenin, since the flavonoids are present in the juices at similar ...
N, Guthrie, K K, Carroll
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