Results 161 to 170 of about 109,261 (241)

Reefense: Living shoreline mosaics can achieve ecological and engineering outcomes with interdisciplinary design. [PDF]

open access: yesProc Natl Acad Sci U S A
Morris RL   +34 more
europepmc   +1 more source

Advancing Malic Acid Production of Aspergillus oryzae: Combined Process Optimization and Application of Various Substrates

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT In light of climate change and growing resource scarcity, microbial production of organic acids offers a sustainable alternative to fossil‐based chemical synthesis. In this study, malic acid production by Aspergillus oryzae was optimized through cultivation temperature adjustment and biotin supplementation, while organic acid formation from ...
Lukas Hartmann   +6 more
wiley   +1 more source

The Interplay of Dispersion and Thermal Shock in Pseudomonas Aeruginosa Biofilms

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Pathological bacterial biofilms formed on medical implants pose a significant challenge in clinical settings due to their resistance to antibiotics and the host immune response. Eradication of these biofilms by thermal shock has gained increasing attention as a means of eliminating these infections.
Hossein Zare, Josiah Power, Eric Nuxoll
wiley   +1 more source

Establishment of a Single‐Cell Minimal Medium: A Case Study for Microfluidic Cultivation of Corynebacterium glutamicum

open access: yesBiotechnology and Bioengineering, EarlyView.
Conventional bulk media are often unsuitable for single‐cell cultivation and analysis because they provide excess nutrients or lack essential components. Redesigning the medium allows for controlled, defined growth, enabling the development of a robust minimal medium that supports quantitative and reproducible single‐cell analysis across different ...
Judith Wegmann   +5 more
wiley   +1 more source

A Mechanistic Model of rAAV Production in Synthetic Cell Lines

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan   +5 more
wiley   +1 more source

Protein Diffusion in Electroporation‐Based Biopsy: Quantifying Protein Transport From Human Skin for Skin Liquid Sampling With Electroporation

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Electroporation‐based biopsy (e‐biopsy) enables minimally invasive extraction of tissue proteins without excision; however, the effective diffusion from tissue into the sampling medium, a key parameter required for this procedure, has not been quantified in human tissues. We coupled time‐resolved aqueous sampling with a one‐dimensional Fickian
Amir Duenyas   +6 more
wiley   +1 more source

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