Research Progress on Nanopolymer Composites in Civil Engineering. [PDF]
Gao T, Zhao Y, Niu Y, Cao X.
europepmc +1 more source
ABSTRACT Messenger ribonucleic acid (mRNA) therapeutics produced by in vitro transcription must be purified to remove residual enzymes and free nucleotides. This study examines the use of high‐performance countercurrent membrane purification (HPCMP) for the purification of mRNA therapeutics based on differences in the rate of diffusion across ...
Ziqiao Wang +3 more
wiley +1 more source
Sustainable Stabilization of Silty Sand Using Recycled Industrial Polymer Reinforcement with a Hybrid Lime-Cement Binder. [PDF]
Lounas A +3 more
europepmc +1 more source
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
BIM-integrated life cycle assessment of decentralized cement-based waste recycling in renovation projects. [PDF]
Younes A +5 more
europepmc +1 more source
Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park +5 more
wiley +1 more source
Probabilistic Carbon Analysis of Pakistan's Bridges Unveils the Urgent Needs of Overdesign Optimization and Policy Transformation. [PDF]
Muhammad HH +5 more
europepmc +1 more source
Real‐Time Biomass Estimation in High‐Density Yeast Fermentations Using Soft Sensor Modeling
Accurate biomass measurements, both offline and online, are essential to improve prediction and control in yeast fermentation. This study develops regression‐based predictive models to correlate offline measurements (Dry Cell Weight and OD600 from a spectrophotometer) with online OD860 probe signals to provide accurate real‐time biomass estimations and
Ana G. Del Hierro +3 more
wiley +1 more source
Adapting the CIERA framework to assess road infrastructure resilience to climate-related events. [PDF]
Doomah Z.
europepmc +1 more source
Model‐Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions
ABSTRACT Mechanistic models are central to quantitative understanding and optimization of Chinese hamster ovary (CHO) cell culture processes, but their utility is often restricted by parameter sets calibrated for specific cell lines, scales, or operating conditions.
Luxi Yu +2 more
wiley +1 more source

