Results 171 to 180 of about 2,946 (220)

Pectinase‐Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development

open access: yesBiotechnology and Bioengineering, EarlyView.
This picture demonstrates a unified strategy for sustainable pectinase production, focusing on microbial bioproduction, innovative strategies in enzyme engineering (Protein engineering, rational enzyme design, directed evolution and heterologous expression) and various applications in industry, including food, textiles, pulp and paper, agriculture and ...
Nisha Sharma   +6 more
wiley   +1 more source

High Cell Density Cultivation of HEK293 Cells Using a 2L Membrane‐Stirred Bioreactor

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The use of perfusion systems for the continuous cultivation of animal cells at high cell density (HCD) for the production of recombinant proteins, viruses, and viral vectors has many advantages. Besides an enhancement of volumetric productivity and high cell viability, the product quality can be improved through a steady‐state environment ...
Lennart Jacobtorweihe   +5 more
wiley   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise   +3 more
wiley   +1 more source

Mitigating Hidden Climate Change Impacts of Timber Cities Critically Depends on Proactive Forest and Waste Management. [PDF]

open access: yesEnviron Sci Technol
Yayla A   +7 more
europepmc   +1 more source

Host Cell Protein Challenges in Antibody Processing: Insights Into Persistence and Mitigation Strategies

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Persistence of HCPs remains a major purification challenge in biopharmaceutical manufacturing with direct consequences for product quality, patient safety, and regulatory compliance. Over the last two decades, deeper insights into the mechanisms driving HCP persistence have clarified why certain proteins evade removal during purification ...
Younghoon Oh   +10 more
wiley   +1 more source

Reefense: Living shoreline mosaics can achieve ecological and engineering outcomes with interdisciplinary design. [PDF]

open access: yesProc Natl Acad Sci U S A
Morris RL   +34 more
europepmc   +1 more source

Expanding Metabolic Online Monitoring Capabilities in 96‐Deepwell Microtiter Plates by Combining Optoelectronic O2 and CO2 Sensors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT To increase the information content in early stages of bioprocess development, various technologies have been introduced for monitoring cultivations in microtiter plates (MTPs). Besides spectroscopical measurements, like in the BioLector technology, optical measurements with luminescent sensors, placed directly in the cultivation medium ...
Robert Dinger   +6 more
wiley   +1 more source

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