Results 91 to 100 of about 7,573 (202)

Genetic Context and Structural Diversity of Class 1 Integrons from Human Commensal Bacteria in a Hospital Intensive Care Unit

, 2011
Most surveys for class 1 integrons are at least partly predicated on PCR screening that targets integron conserved regions. However, class 1 integrons are structurally diverse, so dependence on conserved regions may lead to missing clinically relevant ...
Partridge, SR, Jonathan R. Iredell, Intensive Care Unit, Sally R. Partridge, Thu Betteridge, Iredell, JR, H. W. Stokes, Betteridge, T, Stokes, HW   +8 more
core   +1 more source

Widespread dissemination of class 1 integron components in soils and related ecosystems as revealed by cultivation-independent analysis

Frontiers in Microbiology, 2014
Class 1 integrons contribute to the emerging problem of antibiotic resistance in human medicine by acquisition, exchange, and expression of resistance genes embedded within gene cassettes.
Sven eJechalke, Susanne eSchreiter, Birgit eWolters, Birgit eWolters, Simone eDealtry, Holger eHeuer, Kornelia eSmalla   +6 more
doaj   +1 more source

Mechanism and Molecular Design Principles of Cationic Surfactants: From Charge‐Driven Membrane Interactions to Next‐Generation Quaternary Ammonium Compounds

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Within this review we provide an overview of the social relevance of quaternary ammonium surfactants, different classes of these agents, their interaction mechanism with cellular membranes, structure activity relation, bacterial resistance toward these systems and new approaches to guarantee their long‐term efficiency.
Natalie Hanheiser, Yuhang Jiang, Chuanxiong Nie, Rainer Haag   +3 more
wiley   +1 more source

Diverse aadA gene cassettes on class 1 integrons introduced into soil via spread manure

, 2009
Class 1 integrons are assumed to play an important role in dissemination of antibiotic resistance genes. Class 1 integrons from clinical isolates often have 5′- and 3′-conserved segments flanking the variable region where gene cassettes integrate ...
Binh, Chu-Thi-Thanh, Kaupenjohann, Martin, Heuer, Holger, Smalla, Kornelia   +3 more
core   +1 more source

Temporal dynamics of class 1 and class 3 integron pools in treated wastewater

Water Research
Wastewater is a hotspot for the spread and evolution of antimicrobial resistance (AMR), with integrons playing a key role in the dissemination of AMR. However, there is limited information available regarding the integron pool of wastewater environments.
Rafael D.S. Tavares, Elsa T. Rodrigues, Marta Tacão, Isabel Henriques   +3 more
openaire   +2 more sources

Class 1 integrons in Enterobacteriaceae from farm animals, hospitalized and non-hospitalized patients

, 2006
OBJECTIVE: Class 1 integrons are DNA structures that recognize and capture mobile gene cassettes. A considerable portion of the genes encoding antibiotic resistance is integrated into these DNA elements.
Kosmidis, C.; id_orcid, Avlamis, A., Pasiotou, M., Tzouvelekis, L. S., Vasilakopoulou, A., Daikos, G. L., Charvalos, E., Petrikkos, G.   +7 more
core   +2 more sources

Identification and characterization of class 1 integrons among Pseudomonas aeruginosa isolates from patients in Zhenjiang, China

, 2009
SummaryObjectivesThe role of integrons in the spread of antibiotic resistance has been well established. The aim of this study was to investigate the resistance profiles of Pseudomonas aeruginosa isolated from patients in Zhenjiang to 13 antibiotics, and
Wen, Ping, Dai, Xiaoli, Peng, Sufang, Su, Zhaoliang, Liu, Yingzhao, Huang, Xinxiang, Li, Yazhen, Shao, Qixiang, Wang, Shengjun, Xu, Huaxi, Chen, Jianguo, Zhang, Haifang, Yu, Jianren   +12 more
core   +1 more source

Class 1 integrons in ciprofloxacin-resistant Escherichia coli strains from two Dutch hospitals

, 2005
A significant increase in the isolation frequency of ciprofloxacin-resistant Escherichia coli was observed in the haematology departments of two university hospitals in The Netherlands.
Savelkoul, P.H.M., Schultsz, C, Vandenbroucke-Grauls, CMJE, Schouten, I (I.), Belkum, A. van, Vos, G, Belkum, Alex, Schultsz, C., Van Belkum, A., Savelkoul, PHM, Vandenbroucke-Grauls, C. M. J. E., Savelkoul, P. H. M., Vandenbroucke-Grauls, C.M.J.E., Schouten, I., Mooij, MJ, Mooij, M.J., Vos, G., Mooij, M. J.   +17 more
core   +1 more source

Identical Miniature Inverted Repeat Transposable Elements Flank Class 1 Integrons in Clinical Isolates of Acinetobacter spp. [PDF]

, 2013
Miniature inverted repeat transposable elements (MITEs) have been identified flanking class 1 integrons. We have identified and characterized a 439-bp MITE-like structure in seven Acinetobacter species isolates from Portugal and Brazil.
da Silva, Gabriela J., Nielsen, Kåre M., Toleman, Mark A., Domingues, Sara   +3 more
core   +1 more source

Data_Sheet_1_The large plasmid carried class 1 integrons mediated multidrug resistance of foodborne Salmonella Indiana.DOCX

, 2022
Salmonella enterica serovar Indiana (S. Indiana) has aroused widespread concern as an important zoonotic pathogen. The molecular mechanism of multidrug resistance (MDR) in S. Indiana is not known and should be assessed.
Tian Wang (115287), Chengcheng Zhang (725743), Zongyi Bo (9380594), Xuefeng Wang (113961), Mengjiao Guo (6738158), Yantao Wu (2921832), Guoxiang Chao (13957959)   +6 more
core   +1 more source