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Class 1 integrons as invasive species
Current Opinion in Microbiology, 2017Clinical class 1 integrons are a major contributor to the evolution and dissemination of antibiotic resistance. The conserved motifs of these integrons suggest that a single, recent ancestor gave rise to all current variants. They have had a spectacular increase in distribution and abundance over the last 100 years, exhibiting many similarities to ...
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Diagnostic Microbiology and Infectious Disease, 2010
During 2003 to 2004, class 1 integron was detected in 8 out of 10 tested enterococci isolates, with 2 of them positive for class 2 integron. This is the first report of class 2 integron in Enterococcus faecalis and class 1 integron in Enterococcus faecium.
Zhenbo, Xu +7 more
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During 2003 to 2004, class 1 integron was detected in 8 out of 10 tested enterococci isolates, with 2 of them positive for class 2 integron. This is the first report of class 2 integron in Enterococcus faecalis and class 1 integron in Enterococcus faecium.
Zhenbo, Xu +7 more
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Diversity of class 1 integrons in an aquatic ecosystem
2022The emergence and rapid dissemination of antibiotic resistance is a most striking example of evolution in action, driven by lateral gene transfer. Lateral movement of genetic information is largely mediated by mobile genetic elements such as plasmids, transposons, integrons and genomic islands. These elements are able to move within or between genomes,
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Imipenem-resistant Achromobacter xylosoxidans carrying blaVIM-2-containing class 1 integron
Diagnostic Microbiology and Infectious Disease, 2005We characterized seven isolates of imipenem-resistant Achromobacter xylosoxidans that were isolated from patients hospitalized in the intensive care unit at a tertiary hospital in Korea during 2001 to 2003. From the analysis with an isoelectric focusing, polymerase chain reaction, and sequencing methods, all isolates were found to produce VIM-2, OXA-30,
Kyeong Seob, Shin +7 more
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Detection and Characterization of Class 1 Integrons in Enterohemorrhagic Escherichia coli
Microbial Drug Resistance, 2002Enterohemorrhagic Escherichia coli (EHEC) strains isolated from humans, cattle, and food and belonging to serogroups O26 (7 strains), O111 (19 strains), and O157 (70 strains) were examined for susceptibility to 11 antimicrobial drugs. Fifty-nine strains showing resistance to at least
Morabito S +4 more
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Class 1 integron-associated promoters for gene cassette transcription
Russian Journal of Genetics, 2009In the present paper nucleotide sequences of inner parts of class 1 integrons (natural vectors of cloning and expression of bacterial genes) were determined for the Acinetobacter strains isolated in the Russian medical centres. The similar compositions of inserted gene cassettes are known among the strains disseminated worldwide as minimum as 10 years.
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DNA as a Pollutant: the Clinical Class 1 Integron
Current Pollution Reports, 2018When humans first tried to control bacterial growth with antimicrobials, DNA elements called integrons began to accumulate genes for resistance. The clinical class 1 integron accumulated diverse antibiotic resistance genes, spread into multiple bacterial species, colonized a wide range of animal and plant hosts, and spread to every continent.
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