Results 61 to 70 of about 5,733 (175)
Novel Class 1 Integrons in Multi-drug Resistant Isolates from Eastern China [PDF]
Integrons are mobile genetic elements able to capture, express and excise resistance genes, playing an important role in the spread of bacterial resistance. The present study was to investigate the occurrence and diversity of integrons in 120 clinical multi-drug resistant Gram-negative isolates from eastern China.
Guangming, Sun +5 more
openaire +2 more sources
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula +8 more
wiley +1 more source
A novel hexaplex recombinase polymerase amplification (RPA) method was developed to rapidly and accurately detect five key carbapenemase genes and a Klebsiella pneumoniae‐specific target in a single reaction. This makes it an effective tool for CRKP detection in resource‐constrained environments.
Suthawan Mutitanon +1 more
wiley +1 more source
Clinical isolates of Klebsiella pneumoniae and Enterobacter cloacae complex were analyzed using FT‐IR spectroscopy and genotyping methods. High concordance was observed, demonstrating the potential of FT‐IR spectroscopy as a rapid screening tool.
Yasuhide Kawamoto +9 more
wiley +1 more source
The Evolution of Class 1 Integrons and the Rise of Antibiotic Resistance [PDF]
ABSTRACTClass 1 integrons are central players in the worldwide problem of antibiotic resistance, because they can capture and express diverse resistance genes. In addition, they are often embedded in promiscuous plasmids and transposons, facilitating their lateral transfer into a wide range of pathogens.
Michael, Gillings +6 more
openaire +2 more sources
Iranian clinical Stenotrophomonas maltophilia isolates showed high susceptibility to trimethoprim/sulfamethoxazole, minocycline, and levofloxacin, but marked resistance to ceftazidime and ticarcillin‐clavulanate, alongside widespread biofilm production and resistance genes.
Haneen Fadhil Jasim +6 more
wiley +1 more source
Class 1 and class 2 integrons in avian pathogenic Escherichia coli from poultry in Italy
The aim of this study was to investigate the occurrence of class 1 and 2 integrons in avian pathogenic Escherichia coli (APEC) from poultry in northern Italy. Strains were tested for phenotypic resistance to aminoglycosides and sulphonamides, and the association between the presence of integrons and the resistance to these antimicrobials was evaluated.
L. Cavicchio +7 more
openaire +6 more sources
Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics
Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li +4 more
wiley +1 more source
Antimicrobial resistance, class 1 and 2 integrons and gene cassettes in avian Escherichia coli
Seventy-four Escherichia coli isolates were collected from domestic, synanthropic free living birds as well as wild and exotic birds, all living in captivity.
Patrizia Robino +6 more
doaj +1 more source
This study reveals estragole's bactericidal activity against MDR/XDR Gram‐negative pathogens. Synergy with meropenem and tobramycin was observed in > 88% of strains, reducing antibiotic MICs up to 16‐fold. Estragole represents a promising therapeutic adjuvant to enhance antibiotic efficacy and combat antimicrobial resistance.
María Araque, Luis B. Rojas
wiley +1 more source

