Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex [PDF]
, 2016 Citation: Garcia, B. L., Zhi, H., Wager, B., Hook, M., & Skare, J. T. (2016). Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex. Plos Pathogens, 12(1), 28.
Brandon L. Garcia +4 more
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Transcriptional factor PU.1 regulates decidual C1q expression in early pregnancy in human [PDF]
, 2015 "Copyright: © 2015 Madhukaran, Kishore, Jamil, Teo, Choolani and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Choolani, M +5 more
core +10 more sources
Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]
, 2010 Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H. +4 more
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SALO, a novel classical pathway complement inhibitor from saliva of the sand fly Lutzomyia longipalpis. [PDF]
, 2016 Blood-feeding insects inject potent salivary components including complement inhibitors into their host's skin to acquire a blood meal. Sand fly saliva was shown to inhibit the classical pathway of complement; however, the molecular identity of the ...
Abdeladhim, M. +18 more
core +1 more source
Complement activation and protein adsorption by carbon nanotubes [PDF]
, 2006 As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
core +2 more sources
Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]
, 2015 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K. +10 more
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Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia. [PDF]
, 2019 IntroductionLevels of complement proteins (CPs) in plasma astrocyte-derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI).MethodsParticipants (n = 20 per group) had either MCI ...
Elahi, Fanny M +4 more
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C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation [PDF]
, 2015 Complement C1q is the activator of the classical pathway. However, it is now recognized that C1q can exert functions unrelated to complement activation.
Agostinis, C +9 more
core +2 more sources
Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein [PDF]
, 2012 Human complement factor H-related protein (CFHR) 4 belongs to the factor H family of plasma glycoproteins that are composed of short consensus repeat (SCR) domains.
Hebecker, Mario, Józsi, Mihály
core +1 more source
MafB is a critical regulator of complement component C1q [PDF]
, 2017 The transcription factor MafB is expressed by monocytes and macrophages. Efferocytosis (apoptotic cell uptake) by macrophages is important for inhibiting the development of autoimmune diseases, and is greatly reduced in Mafb-deficient macrophages.
Andrea Christina-Sylvia +24 more
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