Results 111 to 120 of about 387,249 (358)
Deficient Classical Complement Pathway Activity in Newborn Sera [PDF]
Pediatric Research, 1983 Summary: The bactericidal activity of 20 maternal-neonatal paired sera was assessed employing a clinical type la, group B streptococcal isolate, strain 515, known to be opsonized by the classical complement pathway in a non-antibody dependent fashion.
Carol J. Baker +4 more
openaire +3 more sources
The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]
, 2013 Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
core
Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]
, 2019 The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto +5 more
core +1 more source
Advanced Biology, EarlyView.HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang +6 more
wiley +1 more source
Interaction of purified lipoteichoic acid with the classical complement pathway [PDF]
Infection and Immunity, 1986 Glycerophosphate-containing lipoteichoic acids (LTAs) interact with the first component of the classical complement pathway (C1). This resulted in the activation of the classical complement pathway in serum, shown by the consumption of C1, C2, and C4. The dose-dependent interaction of LTAs with purified C1 and C1q was dependent on the negative charges ...
F Clas, Michael Loos, W Fischer
openaire +3 more sources
Advanced Engineering Materials, EarlyView.Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
BMC Complementary Medicine and Therapies, 2022 Introduction Disseminated intravascular coagulation (DIC) is a syndrome characterized by coagulopathy, microthrombus, and multiple organ failure. The complement system in DIC is overactivated, and the functions of complement and coagulation pathways are ...
Qi-Yun Zhang +7 more
doaj +1 more source
Stability of C3 Convertase in the Rat Classical Complement Pathway [PDF]
Microbiology and Immunology, 1997 AbstractIt has been reported that rat serum complement causes efficient hemolysis of antibody‐sensitized sheep erythrocytes (EA) at 20 C but not at 37 C. In connection with this, we demonstrated that C3 convertase of rat complement was significantly unstable at 37 C using purified components of rat complement.
Hidechika Okada, Akihiro Naito
openaire +3 more sources
Advanced Functional Materials, EarlyView.In this study, the interplay of dipolar dynamics and ionic charge transport in MOF compounds is investigated. Synthesizing the novel structure CFA‐25 with integrated freely rotating dipolar groups, local and macroscopic effects, including interactions with Cs cations are explored.
Ralph Freund +6 more
wiley +1 more source
Pathway fractional integral operators involving $\mathtt{k}$-Struve function [PDF]
arXiv, 2016 A new generalization called $\mathtt{k}$-Struve function and its properties given by Nisar and saiful very recently. In this paper, we establish the pathway fractional integral representation of $\mathtt{k}$-Struve function. Many special cases also established to obtain the pathway integral representation of classical Struve function.
arxiv