Results 121 to 130 of about 387,249 (358)

Properdin and factor H: Opposing players on the alternative complement pathway "see-saw" [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund.Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway.
Abdul-Aziz, M, Kishore, U, Kouser, L, Nayak, A, Sim, RB, Stover, CM   +5 more
core   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

Control of Ferromagnetism of Vanadium Oxide Thin Films by Oxidation States

Advanced Functional Materials, EarlyView.
The nonstoichiometric VOx exhibits a distinct ferromagnetic hysteresis loop and demonstrates a high magnetic susceptibility (χ=dMdH$ = \frac{{dM}}{{dH}}\;$∼10). Micromagnetic simulations show the results of the “partial volume fraction ferromagnetic phase model” for VOx/Co/Pt structure.
Kwonjin Park, Jaeyong Cho, Soobeom Lee, Jaehun Cho, Jae‐Hyun Ha, Jinyong Jung, Dongryul Kim, Won‐Chang Choi, Jung‐Il Hong, Chun‐Yeol You   +9 more
wiley   +1 more source

Bothrops snake venoms and their isolated toxins, an L-amino acid oxidase and a serine protease, modulate human complement system pathways

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background Activation of the complement system plays an important role in the regulation of immune and inflammatory reactions, and contributes to inflammatory responses triggered by envenomation provoked byBothrops snakes.
Lorena Rocha Ayres, Alex dos Reis Récio, Sandra Mara Burin, Juliana Campos Pereira, Andrea Casella Martins, Suely Vilela Sampaio, Fabíola Attié de Castro, Luciana Simon Pereira-Crott   +7 more
doaj   +1 more source

Computing Pathways to Systems Biology: Key Contributions of Computational Methods in Pathway Identification [PDF]

arXiv, 2013
Understanding large molecular networks consisting of entities such as genes, proteins or RNAs that interact in complex ways to drive the cellular machinery has been an active focus of systems biology. Computational approaches have played a key role in systems biology by complementing theoretical and experimental approaches.
arxiv  

Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components [PDF]

, 2013
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
A Alitalo, A Alitalo, A Alitalo, A Seling, AC Steere, AM Blom, Andreas Klos, AP van Dam, B Stevenson, C Hammerschmidt, C Siegel, C Siegel, Christine Skerka, Claudia Hammerschmidt, CS Brooks, Dania Richter, E Diza, F Strle, Franz-Rainer Matuschka, H Jiang, H Michel, J Hellwage, J Pietikainen, J Potempa, Jasmin Schwab, JD Lambris, JV McDowell, K Hartmann, K Haupt, K Kurtenbach, K Kurtenbach, K Saito, K Whaley, KM Hovis, KP Hunfeld, L Beinrohr, M Collares-Pereira, M Jusko, M Józsi, MJ Walport, MK Pangburn, MR Bhide, MR Bhide, MR Kenedy, MS Metts, N Marr, ND van Burgel, P Herzberger, P Herzberger, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Ramu, Peter F. Zipfel, Peter Kraiczy, PF Zipfel, PF Zipfel, R Dieterich, R Wallich, Reinhard Wallich, RG Discipio, RJ Ziccardi, S Breitner-Ruddock, S Grosskinsky, S Grosskinsky, S Heinen, S Kühn, SC Bock, SG Rijpkema, SH Rooijakkers, T Fujita, T Fujita, V Brade, Y Terao   +76 more
core   +3 more sources

Scaling‐Up of Structural Superlubricity: Challenges and Opportunities

Advanced Functional Materials, EarlyView.
At increasing length‐scales, structural superlubricity (SSL) faces challenges from physical and chemical energy dissipation pathways. This study reviews recent experimental and theoretical progress on these challenges facing the scaling‐up of SSL, as well as perspectives on future directions for realizing and manipulating macroscale superlubricity ...
Penghua Ying, Xiang Gao, Diana Berman, Oded Hod, Michael Urbakh   +4 more
wiley   +1 more source

Comparing Classical Pathways and Modern Networks: Towards the Development of an Edge Ontology [PDF]

arXiv, 2007
Pathways are integral to systems biology. Their classical representation has proven useful but is inconsistent in the meaning assigned to each arrow (or edge) and inadvertently implies the isolation of one pathway from another. Conversely, modern high-throughput experiments give rise to standardized networks facilitating topological calculations ...
arxiv  

Engineering novel complement activity into a pulmonary surfactant protein [PDF]

, 2010
Complement neutralizes invading pathogens, stimulates inflammatory and adaptive immune responses, and targets non- or altered-self structures for clearance.
Anthony H. Keeble, Brodsky-Doyle, Chen, Chen, Christopher Furze, Daniel A. Mitchell, Doliana, Emsley, Fan, Feinberg, Girija, Haurum, Heise, Hohenester, Hoppe, Jensenius, Julia Toth, Kaufman, Kurata, Phillips, Porter, Reid, Reid, Reid, Russell Wallis, Scherer, Shoulders, Sim, Strang, Teillet, Uemura, Umakhanth Venkatraman Girija, Wallis, Wallis, Wallis, Wallis, Wallis, Wallis, Wilhelm J. Schwaeble   +38 more
core   +2 more sources

Ionic Metal Poly(heptazine Imides) and Single‐Atoms Interplay: Engineered Stability and Performance for Photocatalysis, Photoelectrocatalysis and Organic Synthesis

Advanced Functional Materials, EarlyView.
Poly(heptazine) imides (PHIs), a crystalline carbon nitride subclass, intercalate metals to deliver high stability, tunable electronics, and efficient charge separation. These features enable solar‐driven applications such as hydrogen evolution, CO₂ reduction, and organic synthesis.
Gabriel A. A. Diab, Izadora F. Reis, Chong Wang, Diandra Barreto, Oleksandr Savateev, Ivo F. Teixeira, Pablo Jiménez‐Calvo   +6 more
wiley   +1 more source