Results 141 to 150 of about 61,585 (301)

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Recombinant C1q variants modulate macrophage responses but do not activate the classical complement pathway. [PDF]

Mol Immunol, 2020
Espericueta V, Manughian-Peter AO, Bally I, Thielens NM, Fraser DA.   +4 more
europepmc   +1 more source

Complement Protein C3 Binding toMycobacterium tuberculosisIs Initiated by the Classical Pathway in Human Bronchoalveolar Lavage Fluid [PDF]

, 2004
J. Scott Ferguson, Jeremy J. Weis, Jennifer L. Martin, Larry S. Schlesinger   +3 more
openalex   +1 more source

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Activation of the alternative and classical complement pathways by Entamoeba histolytica

, 1985
J. Calderón, Robert D. Schreiber
openalex   +1 more source

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, EarlyView.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

The Classical Activation Pathway of the Human Complement System Is Specifically Inhibited by Calreticulin from Trypanosoma cruzi [PDF]

, 2004
Viviana P. Ferreira, Carolina Valck, Gittith Sánchez, Alexandre R. Gingras, Sotiria Tzima, Marı́a Carmen Molina, Robert B. Sim, Wilhelm Schwaeble, Arturo Ferreira   +8 more
openalex   +1 more source

The Role of the Complement System Classical and Alternative Pathways in the Pathogenesis of Lacrimal Gland Benign Lymphoepithelial Lesions [PDF]

, 2021
Rui Liu, Jing Li, Mei Sun, Jinjin Wang, Nan Wang, Xuan Zhang, Xin Ge, Jianmin Ma   +7 more
openalex   +1 more source

A Robust Heparin‐Mimicking Polyglycerol‐Based Coating for Blood‐Contacting Devices with Long‐Term Hemocompatibility and Preliminary Anti‐Inflammatory Properties

Advanced Healthcare Materials, EarlyView.
A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu, Philip Nickl, Jun Feng, Rainer Haag   +3 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source