Results 161 to 170 of about 265,122 (221)

The Pleiotropic Effect of Complement C5a-C5aR1 Pathway in Diseases: From Immune Regulation to Targeted Therapy. [PDF]

Int J Mol Sci
Xu B, Zhou Z, Xiao Y, Liu Q, Xiao T, Lv Z, Wang H.   +6 more
europepmc   +1 more source

Critical role of complement in antibody mediated rejection in kidney transplantation. [PDF]

World J Transplant
Abbas K, Mubarak M, Musharraf W, Aziz T, Zafar MN.   +4 more
europepmc   +1 more source

Possible Involvement of Circulating Immune Complex Containing IgG4 in the Pathogenesis of IgG4-Related Disease Complicated by Hypocomplementemia: A Case Report. [PDF]

Int J Mol Sci
Uchida T, Miyake Y, Iwama S, Aoki K, Inoue D, Yamada M, Oda T.   +6 more
europepmc   +1 more source

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Classical complement pathway factor alterations in narcolepsy

Acta Neuropsychiatrica, 2022
AbstractObjective:Narcolepsy is a chronic sleep disorder long hypothesised to be an autoimmune disease. Complement-mediated immune mechanisms have not been investigated in detail in narcolepsy. Our aim was to establish the significance of classical pathway activation in narcolepsy.Methods:Sera of 42 narcolepsy patients and 26 healthy controls were ...
Hande Yüceer, Duygu Gezen Ak, Gülçin Benbir Şenel, Erdinç Dursun, Vuslat Yılmaz, Derya Karadeniz, Erdem Tüzün, Cem İsmail Küçükali   +7 more
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The Classical Complement Pathway: Activation and Regulation of the First Complement Component

Advances in Immunology, 1985
Publisher Summary This chapter focuses on the activation and regulation of the first complement component. . The chapter outlines the history of the classical pathway of the complement system. Clq and C1 are bound and activated by immune complexes or aggregates containing IgG or IgM but not by those containing IgA, IgD, or IgE . Among IgG subclasses,
N. Cooper
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Classical Complement Pathway

2016
Odette Middleton, Helen Wheadon, Alison M. Michie   +2 more
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Classical pathway complement activity in schizophrenia

Neuroscience Letters, 2005
There is considerable evidence to suggest a role for complement in the pathogenesis of schizophrenia, but the data related to the classical pathway complement activity in patients with schizophrenia are conflicting. In the present study, the total hemolytic activity of the complement and the activities of individual complement components, C1, C2, C3 ...
Svetlana, Hakobyan, Anna, Boyajyan, Robert B, Sim   +2 more
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Classical pathway complement activation in Kawasaki syndrome

Journal of Allergy and Clinical Immunology, 1994
In this study the complement breakdown products C3d, C4d, Bb and membrane attack complex were measured in plasma of patients with Kawasaki syndrome. The results suggested strong activation of the classical activation pathway. However, there was no significant decrease in hemolytic titer or in the concentrations of the intact proteins C3, C4, and B. The
T, Kohsaka, J, Abe, T, Asahina, N, Kobayashi   +3 more
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Classical pathway complement activity in Familial Mediterranean fever

Clinical Biochemistry, 2006
The present study emphasizes the important role of the immune reactions in the pathogenesis of Familial Mediterranean fever. In the present study, the total hemolytic activity of the complement and the activities of individual complement components, C1, C2, C3, and C4, were determined in the blood serum of 32 patients with FMF and 28 healthy subjects ...
G M, Mkrtchyan, A S, Boyajyan, A A, Ayvazyan, A A, Beglaryan   +3 more
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