Results 181 to 190 of about 277,934 (283)

Role of the Classical Pathway of Complement Activation in Experimentally Induced Polymicrobial Peritonitis

, 2001
İlhan Çelik, Cordula Stover, Marina Botto, Steffen Thiel, Sotiria Tzima, Dieter Künkel, Mark Walport, W. Lorenz, Wilhelm Schwaeble   +8 more
openalex   +1 more source

C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation [PDF]

, 2008
Katrin Färber, Giselle Cheung, Daniel A. Mitchell, Russell Wallis, Eberhard Weihe, Wilhelm Schwaeble, Helmut Kettenmann   +6 more
openalex   +1 more source

MXene‐Supported Single‐Atom Electrocatalysts

Advanced Science, EarlyView.
This review discusses the characteristics and synthesis of MXenes to elucidate their benefits as support materials. Next, methods and characterization for anchoring SAs onto MXene are discussed. Subsequently, a comprehensive discussion is provided on the recent applications of MXene‐supported SACs in electrocatalysis. Finally, the future challenges and
Jianan He, Joshua D. Butson, Ruijia Gu, Adrian Chun Minh Loy, Qining Fan, Longbing Qu, Gang Kevin Li, Qinfen Gu   +7 more
wiley   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Dominant role of splenic marginal zone lipid rafts in the classical complement pathway against S. pneumoniae. [PDF]

Cell Death Discov, 2019
Yang SW, Park JY, Choi H, Yun TJ, Choi WS, Kim MK, Lee YK, Park M, Jin Y, Joo JS, Choi IS, Park SH, Hwang HS, Kang YS.   +13 more
europepmc   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

Advanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang, Meng‐Die Li, Fan Pan, Wen‐Jia Lei, Yang Xi, Li‐Jun Ling, Leslie Myatt, Kang Sun, Wang‐Sheng Wang   +8 more
wiley   +1 more source

BrkA Protein ofBordetella pertussisInhibits the Classical Pathway of Complement after C1 Deposition

, 2001
Michael Barnes, Alison A. Weiss
openalex   +1 more source

Interactions of complement proteins C1q and factor H with lipid A and Escherichia coli: further evidence that factor H regulates the classical complement pathway [PDF]

, 2011
Lee Aun Tan, Andrew Chung Yang, Uday Kishore, Robert B. Sim   +3 more
openalex   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

Advanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang, Xiaoxue Ruan, Xudong Hang, Ding Heng, Chang Cai, Liping Zeng, Guoxin Zhang, Lu Zhou, Hongkai Bi, Liang Zhang   +9 more
wiley   +1 more source