Results 201 to 210 of about 277,934 (283)

Classical complement pathway activation in the nasal tissue of patients with chronic rhinosinusitis. [PDF]

J Allergy Clin Immunol, 2017
Van Roey GA, Vanison CC, Wu J, Huang JH, Suh LA, Carter RG, Norton JE, Shintani-Smith S, Conley DB, Welch KC, Peters AT, Grammer LC, Harris KE, Hulse KE, Kato A, Stevens WW, Kern RC, Schleimer RP, Tan BK.   +18 more
europepmc   +1 more source

Molluskan Hemocyanins Activate the Classical Pathway of the Human Complement System through Natural Antibodies [PDF]

, 2017
Javier Pizarro-Bäuerle, Ismael Maldonado, Eduardo Sosoniuk-Roche, Gerardo Vallejos, Mercedes López, Flavio Salazar‐Onfray, Lorena Aguilar-Guzmán, Carolina Valck, Arturo Ferreira, Marı́a Inés Becker   +9 more
openalex   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Editorial: State-of-the-Art Research on C1q and the Classical Complement Pathway. [PDF]

Front Immunol, 2016
Kishore U, Thielens NM, Gaboriaud C.
europepmc   +1 more source

PLXDC1+ Tumor‐Associated Pancreatic Stellate Cells Promote Desmoplastic and Immunosuppressive Niche in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
This study uncovers the activation, heterogeneity, and regulatory roles of pancreatic stellate cells (PSCs) at single‐cell and spatial levels. It further identifies PLXDC1+ PSCs near aggressive LRRC15+ cancer‐associated myofibroblasts and SPP1+ macrophages, forming a desmoplastic and immunosuppressive tumor niche that promotes CD8+ T cell exhaustion ...
Yanhua Du, Yizhou Zhao, Judong Li, Jiaxin Wang, Shenglan You, Yao Zhang, Li Zhang, Jihong Yang, Hamid Alinejad‐Rokny, Shujie Cheng, Chenghao Shao, Duowu Zou, Youqiong Ye   +12 more
wiley   +1 more source

Editorial: The Role of Complement in Health and Disease

Frontiers in Immunology, 2019
Maciej Cedzyński, Nicole M. Thielens, Tom Eirik Mollnes, Tom Eirik Mollnes, Tom Eirik Mollnes, Thomas Vorup-Jensen, Thomas Vorup-Jensen   +6 more
doaj   +1 more source

Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia. [PDF]

Hypertension, 2015
Penning M, Chua JS, van Kooten C, Zandbergen M, Buurma A, Schutte J, Bruijn JA, Khankin EV, Bloemenkamp K, Karumanchi SA, Baelde H.   +10 more
europepmc   +1 more source

Killing of dsrA Mutants of Haemophilus ducreyi by Normal Human Serum Occurs via the Classical Complement Pathway and Is Initiated by Immunoglobulin M Binding

, 2005
M. Abdullah, I. Nepluev, G. Afonina, S. Ram, P. Rice, W. Cade, C. Elkins   +6 more
openalex   +2 more sources

Anti-C1s humanized monoclonal antibody SAR445088: A classical pathway complement inhibitor specific for the active form of C1s

, 2023
Ken T. Simmons, Joanne Chan, Sami Hussain, Eileen L. Rose, Kate Markham, Tony Byun, Sandip Panicker, Graham C. Parry, Michael Storek   +8 more
openalex   +1 more source

Multimodal Nanoplasmonic and Fluorescence Imaging for Simultaneous Monitoring of Single‐Cell Secretory and Intracellular Dynamics

Advanced Science, EarlyView.
This study leverages the complementary advantages of label‐free nanoplasmonic biosensing and multichannel fluorescence microscopy to develop a multimodal imaging system for real‐time, spatiotemporal monitoring of cellular activities at the single‐cell level.
Saeid Ansaryan, Yung‐Cheng Chiang, Yen‐Cheng Liu, Patrick Reichenbach, Melita Irving, Hatice Altug   +5 more
wiley   +1 more source