Results 21 to 30 of about 246,399 (165)

Novel Evasion Mechanisms of the Classical Complement Pathway [PDF]

J Immunol, 2016
Brandon L. Garcia, Seline A. Zwarthoff, Suzan H. M. Rooijakkers, Brian V. Geisbrecht   +3 more
europepmc   +3 more sources

Carbamylation of immunoglobulin abrogates activation of the classical complement pathway. [PDF]

Eur J Immunol, 2014
Post‐translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase ...
Koro C, Bielecka E, Dahl-Knudsen A, Enghild JJ, Scavenius C, Brun JG, Binder V, Hellvard A, Bergum B, Jonsson R, Potempa J, Blom AM, Mydel P.   +12 more
europepmc   +2 more sources

Editorial: State-of-the-art research on C1q and the classical complement pathway [PDF]

Front Immunol, 2016
International ...
Duncan, Ghai, Hair, Harmat, Kishore
core   +5 more sources

The Classical Complement Pathway Mediates Microglia-Dependent Remodeling of Spinal Motor Circuits during Development and in SMA. [PDF]

Cell Rep, 2019
Vukojicic A, Delestrée N, Fletcher EV, Pagiazitis JG, Sankaranarayanan S, Yednock TA, Barres BA, Mentis GZ.   +7 more
europepmc   +2 more sources

Classical complement pathway activation in the nasal tissue of patients with chronic rhinosinusitis. [PDF]

J Allergy Clin Immunol, 2017
Van Roey GA, Vanison CC, Wu J, Huang JH, Suh LA, Carter RG, Norton JE, Shintani-Smith S, Conley DB, Welch KC, Peters AT, Grammer LC, Harris KE, Hulse KE, Kato A, Stevens WW, Kern RC, Schleimer RP, Tan BK.   +18 more
europepmc   +2 more sources

Classical complement pathway activation in immune thrombocytopenia purpura: inhibition by a novel C1s inhibitor. [PDF]

Br J Haematol, 2016
Peerschke EI, Panicker S, Bussel J.
europepmc   +2 more sources

Classical Complement Pathway Activation in the Kidneys of Women With Preeclampsia. [PDF]

Hypertension, 2015
Penning M, Chua JS, van Kooten C, Zandbergen M, Buurma A, Schutte J, Bruijn JA, Khankin EV, Bloemenkamp K, Karumanchi SA, Baelde H.   +10 more
europepmc   +2 more sources

A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits activation of the classical complement pathway [PDF]

Virulence, 2023
René Bergmann, Wieland Schroedl, Uwe Müller, Christoph Georg Baums   +3 more
openalex   +2 more sources

Therapeutic Hypothermia Inhibits the Classical Complement Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy [PDF]

Front Neurosci, 2021
Tushar A. Shah, Haree K. Pallera, Cortney L. Kaszowski, W. Thomas Bass, Frank A. Lattanzio   +4 more
openalex   +2 more sources

Covalent association of C3b with C4b within C5 convertase of the classical complement pathway. [PDF]

Journal of Experimental Medicine, 1987
The C5 convertase of the classical complement pathway is a complex enzyme consisting of three complement fragments, C4b, C2a, and C3b. Previous studies have elucidated functional roles of each subunit (4, 6, 7), but little is known about how the subunits
Y. Takata, Tsuguki Kinoshita, Haruo Kozono, Junji Takeda, Etsuko Tanaka, K Hong, Kozo Inoue   +6 more
openalex   +2 more sources