Results 61 to 70 of about 265,122 (221)

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats. [PDF]

PLoS ONE, 2015
The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic modulators of the classical, lectin and alternative pathways of the complement system are ...
Julia A Sharp, Pamela S Hair, Haree K Pallera, Parvathi S Kumar, Clifford T Mauriello, Julius O Nyalwidhe, Cody A Phelps, Dalnam Park, Nicole M Thielens, Stephen M Pascal, Waldon Chen, Diane M Duffy, Frank A Lattanzio, Kenji M Cunnion, Neel K Krishna   +14 more
doaj   +1 more source

Blood platelets activate the classical pathway of human complement [PDF]

Journal of Thrombosis and Haemostasis, 2006
Activation of the complement system plays a key role in inflammation associated with vascular injury. Recently, platelet P-selectin was shown to activate C3 via the alternative pathway of human complement. As platelets also posses binding sites for C1q, the recognition unit of the classical complement pathway, the present study examined classical ...
E I B, Peerschke, W, Yin, S E, Grigg, B, Ghebrehiwet   +3 more
openaire   +2 more sources

A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system [PDF]

, 2008
The M protein of Streptococcus equi subsp. equi known as fibrinogen-binding protein (FgBP) is a cell wall-associated protein with antiphagocytic activity that binds IgG. Recombinant versions of the seven equine IgG subclasses were used to investigate the
Abi-Rached, Berge, Boschwitz, Boschwitz, Bruggemann, Burton, Burton, Carlsson, Deisenhofer, DeLano, Flock, Flock, Galan, Galan, Galan, Ghetie, Harrington, Herr, Jonsson, Lancet, Lewis, Lindmark, Meehan, Meehan, Meehan, Meehan, Meehan, Morton, Newton, Nitsche-Schmitz, Pleass, Pleass, Ramsland, Recht, Sauer-Eriksson, Sheoran, Sheoran, Taylor, Timoney, Timoney, Timoney, van Loghem, Wagner, Wagner, Wagner, Waller, Wines, Wines, Wolbink, Åkerström   +49 more
core   +4 more sources

Human pentraxin 3 binds to the complement regulator c4b-binding protein. [PDF]

PLoS ONE, 2011
The long pentraxin 3 (PTX3) is a soluble recognition molecule with multiple functions including innate immune defense against certain microbes and the clearance of apoptotic cells.
Anne Braunschweig, Mihály Józsi
doaj   +1 more source

Classical and alternate complement factor overexpression in non-obese weight matched women with polycystic ovary syndrome does not correlate with vitamin D

Frontiers in Endocrinology, 2022
IntroductionWomen with polycystic ovary syndrome (PCOS) exhibit complement factor expression changes that may be obesity-driven rather than an intrinsic facet of PCOS; furthermore, complement changes have been associated with vitamin D deficiency, a ...
Abu Saleh Md Moin, Thozhukat Sathyapalan, Alexandra E. Butler, Stephen L. Atkin   +3 more
doaj   +1 more source

Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review. [PDF]

, 2014
Chronic indwelling catheters have been reported to be associated with membranoproliferative glomerulonephritis (MPGN) via the activation of the classical complement pathway in association with bacterial infections such as coagulase negative ...
Nast, Cynthia C, Pham, Phuong-Chi T, Pham, Phuong-Thu T, Sy, John   +3 more
core   +2 more sources

Preanalytical classical and alternative complement pathway activity loss

Biochemia medica, 2019
Introduction: Complement functional analyses provide insight into the integrity of the entire complement reaction cascade. These tests are suitable for investigating suspected complement deficiencies. Falsely reduced test outcomes may result from preanalytical instabilities of individual complement components.
Vercauteren, Koen O.A., Lambrecht, Stijn, Delanghe, Joris   +2 more
openaire   +2 more sources

Mechanisms to Evade the Phagocyte Respiratory Burst Arose by Convergent Evolution in Typhoidal Salmonella Serovars. [PDF]

, 2018
Typhoid fever caused by Salmonella enterica serovar (S.) Typhi differs in its clinical presentation from gastroenteritis caused by S. Typhimurium and other non-typhoidal Salmonella serovars.
Bäumler, Andreas J, Cobb, Brian A, Hiyoshi, Hirotaka, Lock, Gabriel, Raffatellu, Manuela, Saechao, Cheng, Wangdi, Tamding   +6 more
core   +2 more sources

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]

, 2020
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P., Leuvenink, Henri G. D., Nieuwenhuijs-Moeke, Gertrude J., Pischke, Soren E., Ploeg, Rutger J., Pol, Robert A., Sanders, Jan Stephan F., Struys, Michel   +7 more
core   +2 more sources

Differential Gene Expression in Liver, Gill, and Olfactory Rosettes of Coho Salmon (Oncorhynchus kisutch) After Acclimation to Salinity. [PDF]

, 2015
Most Pacific salmonids undergo smoltification and transition from freshwater to saltwater, making various adjustments in metabolism, catabolism, osmotic, and ion regulation. The molecular mechanisms underlying this transition are largely unknown.
Bammler, Theo K, Beyer, Richard P, Farin, Federico M, Gallagher, Evan P, Hardiman, Gary, Lavado, Ramon, Maryoung, Lindley A, Schlenk, Daniel, Stapleton, Patricia L   +8 more
core   +1 more source