Results 71 to 80 of about 248,487 (359)

Human complement factor H. Two factor H proteins are derived from alternatively spliced transcripts [PDF]

open access: yes, 1991
The human complement factor H is an important component in the control of the alternative pathway of complement activation. We have previously shown that at least three factor H homologous mRNA species of 4.3 kb, 1.8 kb and 1.4 kb in length are ...
Alsenz   +23 more
core   +1 more source

Innate immunity and neuroinflammation [PDF]

open access: yes, 2013
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Bonifati, DM, Kishore, U, Shastri, A
core   +3 more sources

Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats. [PDF]

open access: yesPLoS ONE, 2015
The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic modulators of the classical, lectin and alternative pathways of the complement system are ...
Julia A Sharp   +14 more
doaj   +1 more source

Different Complement Activation Pathways Underly Cognitive Impairment and Type 2 Diabetes Mellitus Combined With Cognitive Impairment

open access: yesFrontiers in Aging Neuroscience, 2022
BackgroundThe immune response and the complement system are associated with cognitive impairment and diabetes mellitus, respectively. Activation of the complement system in these diseases occurs mainly through either the classical pathway or the ...
Zhenxing Li   +7 more
doaj   +1 more source

Human pentraxin 3 binds to the complement regulator c4b-binding protein. [PDF]

open access: yesPLoS ONE, 2011
The long pentraxin 3 (PTX3) is a soluble recognition molecule with multiple functions including innate immune defense against certain microbes and the clearance of apoptotic cells.
Anne Braunschweig, Mihály Józsi
doaj   +1 more source

A Systematic Investigation on Complement Pathway Activation in Diabetic Retinopathy

open access: yesFrontiers in Immunology, 2020
The complement system plays a crucial role in retinal homeostasis. While the proteomic analysis of ocular tissues in diabetic retinopathy (DR) has shown the deposition of complement proteins, their exact role in the pathogenesis of DR is yet unclear.
Shahna Shahulhameed   +7 more
semanticscholar   +1 more source

Classical and alternate complement factor overexpression in non-obese weight matched women with polycystic ovary syndrome does not correlate with vitamin D

open access: yesFrontiers in Endocrinology, 2022
IntroductionWomen with polycystic ovary syndrome (PCOS) exhibit complement factor expression changes that may be obesity-driven rather than an intrinsic facet of PCOS; furthermore, complement changes have been associated with vitamin D deficiency, a ...
Abu Saleh Md Moin   +3 more
doaj   +1 more source

Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review. [PDF]

open access: yes, 2014
Chronic indwelling catheters have been reported to be associated with membranoproliferative glomerulonephritis (MPGN) via the activation of the classical complement pathway in association with bacterial infections such as coagulase negative ...
Nast, Cynthia C   +3 more
core   +2 more sources

Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]

open access: yes, 2020
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P.   +7 more
core   +2 more sources

Characterization of the Classical Complement Pathway of Rainbow Trout [PDF]

open access: yesJournal of the Faculty of Agriculture, Kyushu University, 1988
Characteristics of the classical complement pathway (CCP) of rainbow trout Salmo gairdneti was examined using sheep red blood cells sensitized with porgy Pagrms major antibody which is compatible with rainbow trout complement. The rainbow trout CCP showed the highest activity when the reaction was performed at 20-25°C and around pH 7.5, and the ...
Tomoki Yano, Miki Nakao
openaire   +1 more source

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