Results 31 to 40 of about 137,516 (336)

Blood monocytes and their subsets: established features and open questions

Frontiers in Immunology, 2015
In contrast to the past reliance on morphology the identification and enumeration of blood monocytes is nowadays done with monoclonal antibodies and flow cytometry and this allows for subdivision into classical, intermediate and non-classical monocytes ...
Loems eZiegler-Heitbrock
doaj   +1 more source

Expression of M2-associated molecules in circulating monocyte subsets in fertile non-pregnant women and pregnant women with uncomplicated pregnancy

Медицинская иммунология, 2022
In humans circulating monocytes include classical (CD14++CD16- ), intermediate (CD14++CD16+) and non-classical/alternative (CD14+CD16++) monocytes, which in turn can be activated via the classical or alternative pathway.
E. Ya. Shevela, N. G. Bukhtueva, M. A. Tikhonova, O. Yu. Leplina, N. M. Pasman, E. R. Chernykh   +5 more
doaj   +1 more source

Altered monocyte expression and expansion of non-classical monocyte subset in IgA nephropathy patients [PDF]

Nephrology Dialysis Transplantation, 2015
The main defect of immunoglobulin A nephropathy (IgAN) lies within the immune system and in peripheral blood mononuclear cells rather than in the kidney. Previously, we found an altered gene expression in monocytes compared with B and T cells isolated from IgAN patients; thus, our aim here has been to study this subset at a genome-wide and functional ...
Cox, Sharon N., Serino, Grazia, Sallustio, Fabio, BLASI, ANTONELLA, Rossini, Michele, Pesce, Francesco, Schena, Francesco Paolo   +6 more
openaire   +3 more sources

Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes [PDF]

, 2017
BACKGROUND: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of interferon (IFN)-regulatory genes and inflammatory cytokines, suggesting dysregulation of the ...
Dreyfus, David H., FAGGIONI, Alberto, FARINA, Antonella, Farina, G. Alessandra, Lacconi, Valentina, Lenna, Stefania, MORRONE, Stefania, PERUZZI, Giovanna, QUARTA, SILVIA, ROSATO, Edoardo, Trojanowska, Maria, VESTRI, Anna Rita, York, Michael   +12 more
core   +1 more source

The classical nature of distinctive CMML monocytes [PDF]

Blood, 2017
In this issue of Blood, Talati et al use multiparameter flow cytometry to immunophenotypically characterize peripheral blood cells of patients with chronic myelomonocytic leukemia (CMML) as being comprised of a quantitatively increased subset of the disease9s hallmark cells, the classical monocytes.1 This finding provides an additive marker for ...
openaire   +2 more sources

Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]

, 2012
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
A Kadioglu, A Kadioglu, A Nalbant, A Strasser, AD Badley, Andrea M. Mitchell, C Riccardi, CA Janeway Jr, CK Sung, D Zhou, David H. Dockrell, DH Dockrell, DH Dockrell, DH Dockrell, DR Cundell, EE McGrath, FK Swirski, Frank R. DeLeo, G Matute-Bello, Helen M. Marriott, HM Marriott, HM Marriott, I Nicoletti, J Warwick-Davies, JA Carrero, Julie A. Preston, K Beiter, K Kemp, K LeMessurier, KA Browne, KE Price, L Galluzzi, L Maggi, L Ziegler-Heitbrock, LA Kirkham, M Daigneault, M Lenardo, M Witzenrath, MA Barocchi, MA Bewley, Marc Daigneault, Martin A. Bewley, MJ Jedrzejas, Moira K. B. Whyte, N Olivares-Zavaleta, N Oyaizu, NV Serbina, PA Kiener, R Malley, RA Hirst, Robert C. Read, RS Hotchkiss, RS Hotchkiss, RS Hotchkiss, SE Weber, SJ Webster, SL Newman, T Mattern, T Takahashi, Thushan I. De Silva, Timothy J. Mitchell, WL Farrar, WP Hausdorff, YJ Lu, Z Zhang   +64 more
core   +4 more sources

Towards a refined definition of monocyte subsets

Frontiers in Immunology, 2013
In a nomenclature proposal published in 2010 monocytes were subdivided into classical and nonclassical cells and in addition an intermediate monocyte subset was proposed.
Loems eZiegler-Heitbrock, Thomas PJ Hofer   +1 more
doaj   +1 more source

Monocyte subsets display age-dependent alterations at fasting and undergo non-age-dependent changes following consumption of a meal

Immunity & Ageing, 2022
Background Monocytes are a heterogenous population of immune cells whose subsets and functions become substantially dysregulated with advanced age. Although much of our current understanding of the age-related changes in monocytes is derived from fasting
Ryan G. Snodgrass, Xiaowen Jiang, Charles B. Stephensen   +2 more
doaj   +1 more source

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. [PDF]

, 2016
Monocytes play a central role in regulating inflammation in response to infection or injury, and during auto-inflammatory diseases. Human blood contains classical, intermediate and non-classical monocyte subsets that each express characteristic patterns ...
A MacKenzie, A Piccini, AA Sharma, AM Knapinska, AM Zawada, B Passlick, C Antonopoulos, CA Dinarello, D Kontoyiannis, D Perregaux, DJ Stumpo, E Carballo, E Shantsila, E Vigano, E Wang, F Martinon, G Buell, G Laroia, G Shaw, GM Wilson, IA Vlasova, J Cros, J Maelfait, JA Hagar, JH Edwan, JR Ward, JY Lu, JY Lu, KL Wong, KL Wong, KS Sinsimer, L Ziegler-Heitbrock, M Alfaidi, ME Edye, MG Netea, N Kayagaki, N Marina-Garcia, N Sadri, P Ancuta, P Ivanov, P Pelegrin, P Pelegrin, P Pelegrin, RA Black, RG Snodgrass, SD Wright, T Kastelic, T Takenouchi, T Takenouchi, VA Rathinam, WP Arend, Y Qu, YL Chen, ZJ Shen   +53 more
core   +1 more source

Relationship between the functional activity of in vitro generated monocyte-derived dendritic cells and the presence of CD16 ⁺ cells among peripheral blood monocytes

Медицинская иммунология, 2020
Peripheral blood monocytes are heterogeneous CD14+ cell population, some of which also express CD16 molecule. Differences in phenotype between monocyte subpopulations can affect their functional activity, as well as the ability to further differentiate ...
T. V. Tyrinova, O. Yu. Leplina, M. A. Tikhonova, L. V. Sakhno, A. A. Maximova, А. A. Ostanin, E. R. Chernykh   +6 more
doaj   +1 more source