Solid phase enzyme linked immunosorbent assay for classical complement activation pathway. [PDF]
Mikael Rhen
openalex +1 more source
CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline
ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad+7 more
wiley +1 more source
Different Aspects of Classical Pathway Overactivation in Patients With C3 Glomerulopathy and Immune Complex-Mediated Membranoproliferative Glomerulonephritis. [PDF]
Michels MAHM+11 more
europepmc +1 more source
Activation of the alternative and classical complement pathways by Entamoeba histolytica [PDF]
J. Calderón, Robert D. Schreiber
openalex +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach+11 more
wiley +1 more source
Antibodies play an essential role in preserving intestinal homeostasis in healthy and dysbiotic states. Recent studies demonstrate that a microbiome-dependent intestine-specific complement system maintains intestinal homeostasis.
Nicolas Vitari+7 more
doaj +1 more source
Inhibition of the Classical Pathway of Complement Activation Impairs Bacterial Clearance during Enterococcus faecalis Infection. [PDF]
Shehab El-Din EMR+3 more
europepmc +1 more source
Optimum Conditions for the Assay of the Classical Pathway-Complement Titer of Tilapia (Tilupia nilotica) Serum [PDF]
Tomoki Yano+3 more
openalex +1 more source
ABSTRACT Objective SCN1A‐related seizures first present as febrile seizures (FS). Definitive features emerge later, making early diagnosis challenging. We evaluated the diagnostic yield and clinical characteristics of pathogenic SCN1A variants in FS, and analyzed the effect of variant characteristics on clinical phenotypes required for early ...
Jia Wang+11 more
wiley +1 more source
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova+5 more
wiley +1 more source