Results 51 to 60 of about 22,637 (212)
Determinants of Virulence of Classical Swine Fever Virus Strain Brescia [PDF]
ABSTRACT Two related classical swine fever virus (CSFV) strain Brescia clones were isolated from blood samples from an infected pig. Virus C1.1.1 is a cell-adapted avirulent variant, whereas CoBrB is a virulent variant. Sequence analysis revealed 29 nucleic acid mutations in C1.1.1, resulting in 9 amino acid substitutions ...
van Gennip, H.G.P. +4 more
openaire +2 more sources
Germ Panic and Chalice Hygiene in the Church of England, c.1895–1930
The late‐Victorian medical revolution in bacteriology, and growing public awareness of hygienic standards and the danger of disease infection from germs, created alarm about the traditional Christian practice of drinking from a common cup at Holy Communion.
Andrew Atherstone
wiley +1 more source
Classical swine fever virus nonstructural protein p7 modulates infectious virus production [PDF]
AbstractThe classical swine fever virus (CSFV) nonstructural protein p7 is crucial for virus production, yet precisely how the p7 modulates this process is unclear. In this study, we first identified the interactions of p7 with E2 and NS2. The key binding regions of both p7 and NS2 mapped to the first transmembrane (TM1) domain of two proteins.
Zhao, Cheng +4 more
openaire +2 more sources
Rate of inter-herd transmission of classical swine fever virus by different types of contact during the 1997-8 epidemic in The Netherlands [PDF]
In this study we quanti®ed the rate at which classical swine fever had been transmitted by several different types of inter-herd contact during the 1997±8 epidemic in The Netherlands. During that epidemic 428 CSFV-infected pig herds were detected, 403 of
Bouma, A. +3 more
core +2 more sources
A novel kirkovirus may be associated with equine gastrointestinal disease
Abstract Background Many cases of equine enterocolitis are suspected to be infectious in nature, but no pathogen is identified in many cases. Objectives Perform next‐generation sequencing on faeces collected from cases of equine enterocolitis for the presence of novel viruses and determine if an identified novel virus is associated with cases of equine
Lillian M. B. Haywood +3 more
wiley +1 more source
Abstract The currently circulating high‐pathogenicity avian influenza (HPAI) virus of the subtype H5 causes variable illness and death in wild and domestic birds and mammals, as well as in humans. This virus evolved from the Goose/Guangdong lineage of the HPAI H5 virus, which emerged in commercial poultry in China in 1996, spilled over into wild birds,
Thijs Kuiken +9 more
wiley +1 more source
Reemergence of Classical Swine Fever, Japan, 2018
In September 2018, classical swine fever reemerged in Japan after 26 years, affecting domestic pigs and wild boars. The causative virus belongs to the 2.1 subgenotype, which caused repeated outbreaks in eastern and Southeast Asia.
Alexander Postel +5 more
doaj +1 more source
African swine fever (ASF), caused by the African swine fever virus (ASFV), is an acute, deadly, infectious disease of domestic pigs and wild boars and has a tremendous negative socioeconomic impact on the swine industry.
Yongshu Wu +10 more
doaj +1 more source
Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei +11 more
wiley +1 more source
Interaction of classical swine fever virus with dendritic cells
Functional disruption of dendritic cells (DCs) is an important strategy for viral pathogens to evade host defences. Monocytotropic viruses such as classical swine fever virus (CSFV) could employ such a mechanism, since the virus can suppress immune responses and induce apoptosis without infecting lymphocytes.
Carrasco, C.P. +11 more
openaire +2 more sources

