Results 11 to 20 of about 134,599 (345)

Host Factors Genes BcCLC1 and BcCLC2 Confer Turnip Mosaic Virus Resistance in Non-Heading Chinese Cabbage (Brassica campestris ssp. chinensis)

Plants, 2023
Clathrin is an evolutionarily highly conserved evolutionary protein consisting of clathrin light chains (CLC) and clathrin heavy chains (CHC), and these form its basic structure. Clathrin is an important host factor in the process of viral infection.
Mengguo Yuan, Shanwu Lyu, Yaolong Wang, Liu E, Tongkun Liu, Xilin Hou, Ying Li, Changwei Zhang   +7 more
doaj   +1 more source

The structure and spontaneous curvature of clathrin lattices at the plasma membrane

bioRxiv, 2020
Clathrin mediated endocytosis is the primary pathway for receptor and cargo internalization in eukaryotic cells. It is characterized by a polyhedral clathrin lattice that coats budding membranes.
Kem A. Sochacki, Bridgette L. Heine, Gideon J Haber, J. Jimah, Bijeta Prasai, Marco A. Alfonzo-Méndez, Aleah D Roberts, Agila Somasundaram, J. Hinshaw, Justin W. Taraska   +9 more
semanticscholar   +1 more source

Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166

Nature Communications, 2020
While several clathrin-independent endocytic processes have been described so far, their biological relevance often remains elusive, especially in pathophysiological contexts such as cancer.
Henri‐François Renard, François Tyckaert, Cristina Lo Giudice, Thibault Hirsch, C. A. Valades-Cruz, Camille Lemaigre, Massiullah Shafaq-Zadah, C. Wunder, R. Wattiez, L. Johannes, P. van der Bruggen, D. Alsteens, P. Morsomme   +12 more
semanticscholar   +1 more source

Hsc70-induced changes in clathrin-auxilin cage structure suggest a role for clathrin light chains in cage disassembly [PDF]

, 2013
The molecular chaperone, Hsc70, together with its co-factor, auxilin, facilitates the ATP-dependent removal of clathrin during clathrin-mediated endocytosis in cells.
Brodsky, Frances M., Harvey-Smith, Phillip, Kent, Helen, Pearse, Barbara M. F., Ranson, Neil, Roseman, Alan, Rothnie, Alice, Smith, Corinne J., Stoilova-McPhie, Svetla, Vallis, Yvonne, Young, Anna   +10 more
core   +2 more sources

Hepatitis B virus entry into HepG2‐NTCP cells requires clathrin‐mediated endocytosis

Cellular Microbiology, 2020
Hepatitis B virus (HBV) is a leading cause of cirrhosis and hepatocellular carcinoma worldwide, with 250 million individuals chronically infected. Many stages of the HBV infectious cycle have been elucidated, but the mechanisms of HBV entry remain poorly
Charline Herrscher, Florentin Pastor, Julien Burlaud‐Gaillard, Amélie Dumans, Florian Seigneuret, A. Moreau, R. Patient, Sébastien Eymieux, H. de Rocquigny, C. Hourioux, P. Roingeard, Emmanuelle Blanchard   +11 more
semanticscholar   +1 more source

Characterization of a temperature-sensitive vertebrate clathrin heavy chain mutant as a tool to study clathrin-dependent events in vivo.

PLoS ONE, 2010
Clathrin and clathrin-dependent events are evolutionary conserved although it is believed that there are differences in the requirement for clathrin in yeast and higher vertebrates. Clathrin is a long-lived protein and thus, with clathrin knockdowns only
Petra Neumann-Staubitz, Stephanie L Hall, Joseph Kuo, Antony P Jackson   +3 more
doaj   +1 more source

Pitstop‐2 and its novel derivative RVD‐127 disrupt global cell dynamics and nuclear pores integrity by direct interaction with small GTPases

Bioengineering & Translational Medicine, 2023
Clathrin‐mediated endocytosis (CME) is an essential cell physiological process of broad biomedical relevance. Since the recent introduction of Pitstop‐2 as a potent CME inhibitor, we and others have reported on substantial clathrin‐independent inhibitory
Ivan Liashkovich, Sílvio Terra Stefanello, Reshma Vidyadharan, Günter Haufe, Alexander Erofeev, Peter V. Gorelkin, Vasilii Kolmogorov, Caren Rigon Mizdal, Alexander Dulebo, Etmar Bulk, Ian U. Kouzel, Victor Shahin   +11 more
doaj   +1 more source

Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers

Cell Reports, 2012
Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the ...
Comert Kural, Silvia K. Tacheva-Grigorova, Steeve Boulant, Emanuele Cocucci, Thorsten Baust, Delfim Duarte, Tom Kirchhausen   +6 more
doaj   +1 more source

Clathrin is spindle-associated but not essential for mitosis.

PLoS ONE, 2008
BackgroundClathrin is a multimeric protein involved in vesicle coat assembly. Recently clathrin distribution was reported to change during the cell cycle and was found to associate with the mitotic spindle.
Joana Borlido, Greg Veltri, Antony P Jackson, Ian G Mills   +3 more
doaj   +1 more source

Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

Journal of Extracellular Vesicles, 2020
Pregnancy is a unique situation, in which placenta-derived small extracellular vesicles (sEVs) may communicate with maternal and foetal tissues. While relevant to homoeostatic and pathological functions, the mechanisms underlying sEV entry and cargo ...
Hui Li, Itziar Pinilla-Macua, Yingshi Ouyang, Elena Sadovsky, Kazuhiro Kajiwara, Alexander Sorkin, Yoel Sadovsky   +6 more
doaj   +1 more source