Results 11 to 20 of about 135,129 (369)

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks [PDF]

Nature Communications
Clathrin-mediated endocytosis is essential for membrane traffic, impacting a diverse range of cellular processes including cell signaling homeostasis, cell adhesion, and receptor recycling.
Brandon T. Malady, Andromachi Papagiannoula, Advika Kamatar, Susovan Sarkar, Gavin T. Lebrun, Liping Wang, Carl C. Hayden, Eileen M. Lafer, David J. Owen, Sigrid Milles, Jeanne C. Stachowiak   +10 more
doaj   +3 more sources

Characterization of Zika Virus Endocytic Pathways in Human Glioblastoma Cells [PDF]

Frontiers in Microbiology, 2020
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Mei Li, Mei Li, Di Zhang, Di Zhang, Chuntian Li, Chuntian Li, Zifeng Zheng, Zifeng Zheng, Ming Fu, Ming Fu, Fengfeng Ni, Fengfeng Ni, Yalan Liu, Tao Du, Hanzhong Wang, George E. Griffin, Mudan Zhang, Qinxue Hu, Qinxue Hu   +18 more
doaj   +3 more sources

A functional study of AUXILIN-LIKE1 and 2, two putative clathrin uncoating factors in Arabidopsis [PDF]

The Plant Cell, 2018
Clathrin-mediated endocytosis (CME) is a cellular trafficking process in which cargoes and lipids are internalized from the plasma membrane into vesicles coated with clathrin and adaptor proteins. CME is essential for many developmental and physiological
Adamowski, Maciek, De Jaeger, Geert, Friml, Jiri, Glanc, Matous, Kania, Urszula, Narasimhan, Madhumitha   +5 more
core   +3 more sources

Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers

Cell Reports, 2012
Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the ...
Comert Kural, Silvia K. Tacheva-Grigorova, Steeve Boulant, Emanuele Cocucci, Thorsten Baust, Delfim Duarte, Tom Kirchhausen   +6 more
doaj   +3 more sources

Architecture of the AP2:clathrin coat on the membranes of clathrin-coated vesicles [PDF]

Science Advances, 2020
Cryo-electron tomography reveals the conformational changes and clathrin interactions of AP2 during coated vesicle assembly. Clathrin-mediated endocytosis (CME) is crucial for modulating the protein composition of a cell’s plasma membrane. Clathrin forms
Oleksiy Kovtun, Veronica Kane Dickson, B.T. Kelly, David J. Owen, John A. G. Briggs   +4 more
semanticscholar   +3 more sources

Weak Molecular Interactions in Clathrin-Mediated Endocytosis

Frontiers in Molecular Biosciences, 2017
Clathrin-mediated endocytosis is a process by which specific molecules are internalized from the cell periphery for delivery to early endosomes. The key stages in this step-wise process, from the starting point of cargo recognition, to the later stage of
Sarah M. Smith, Michael Baker, Mary Halebian, Corinne J. Smith   +3 more
doaj   +2 more sources

Mechanoregulation of clathrin-mediated endocytosis [PDF]

Journal of Cell Science, 2017
Joshua P. Ferguson, Scott D. Huber, Nathan M. Willy, Esra Aygün, Sevde Goker, Tuğba Atabey, Cömert Kural   +6 more
openalex   +2 more sources

A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly. [PDF]

PLoS ONE, 2016
The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin binding motifs to assemble clathrin triskelia into cages. However, the precise mechanism of clathrin assembly is not yet known.
Lia Moshkanbaryans, Jing Xue, Jesse Ray Wark, Phillip James Robinson, Mark Evan Graham   +4 more
doaj   +1 more source

A CIE change in our understanding of endocytic mechanisms

Frontiers in Cell and Developmental Biology, 2023
The past six decades have seen major advances in our understanding of endocytosis, ranging from descriptive studies based on electron microscopy to biochemical and genetic characterization of factors required for vesicle formation.
Daniel J. Rioux, Daniel J. Rioux, Derek C. Prosser   +2 more
doaj   +1 more source

Dynamics and nanoscale organization of the postsynaptic endocytic zone at excitatory synapses

eLife, 2022
At postsynaptic sites of neurons, a prominent clathrin-coated structure, the endocytic zone (EZ), controls the trafficking of glutamate receptors and is essential for synaptic plasticity.
Lisa AE Catsburg, Manon Westra, Annemarie ML van Schaik, Harold D MacGillavry   +3 more
doaj   +1 more source