Results 11 to 20 of about 126,267 (387)
Dynamics of Intracellular Clathrin/AP1- and Clathrin/AP3-Containing Carriers
Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the ...
Comert Kural+6 more
doaj +4 more sources
Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites. [PDF]
Three monoclonal antibodies that react with previously undefined antigenic determinants on the clathrin molecule have been produced and characterized. They were isolated from a fusion between myeloma cells and popliteal lymphocytes from SJL mice that had
Brodsky, Frances
core +3 more sources
Characterization of anti‐clathrin serum [PDF]
Coated vesicles (CVs), membrane bilayers enclosed by polygonal protein lattices, are ubiquitous cellular organelles which are involved in a variety of membrane transfer processes [l-S]. Recently, Pearse has isolated CVs from several different mammalian tissues [6,7]. They contain a major protein component, clathrin, a mol.
David H. Sack+2 more
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Assembled clathrin in erythrocytes.
Clathrin cages were isolated from rat erythrocytes. These structures exist in the intact cell as demonstrated by immunofluorescence and were not formed during the isolation procedure. The cages were largely devoid of membrane but contained the assembly protein complex and both the 50-kDa kinase (pp50) and casein kinase II activities found previously in
Andrew E. Levin+2 more
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Clathrin exchange during clathrin-mediated endocytosis [PDF]
During clathrin-mediated endocytosis, clathrin-coated pits invaginate to form clathrin-coated vesicles (CVs). Since clathrin-coated pits are planar structures, whereas CVs are spherical, there must be a structural rearrangement of clathrin as invagination occurs.
Shivani Kaushal+5 more
openaire +2 more sources
Brain clathrin and clathrin-associated proteins. [PDF]
The assembly of clathrin into baskets or cages in vitro may depend on formation of complex between clathrin and a polypeptide doublet migrating in the 30000-mol.wt. region. Clathrin with several associated proteins was isolated from coated-vesicle fractions of bovine cerebral cortex.
N Moskowitz+4 more
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Clathrin Adaptor GGA1 Polymerizes Clathrin into Tubules [PDF]
GGAs, a class of monomeric clathrin adaptors, are involved in the sorting of cargo at the trans-Golgi network of eukaryotic cells. They are modular structures consisting of the VHS, the GAT, hinge, and GAE domains, which have been shown to interact directly with cargo, ARF, clathrin, and accessory proteins, respectively.
Mark Norton+5 more
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Clathrin is an evolutionarily highly conserved evolutionary protein consisting of clathrin light chains (CLC) and clathrin heavy chains (CHC), and these form its basic structure. Clathrin is an important host factor in the process of viral infection.
Mengguo Yuan+7 more
doaj +1 more source
A CIE change in our understanding of endocytic mechanisms
The past six decades have seen major advances in our understanding of endocytosis, ranging from descriptive studies based on electron microscopy to biochemical and genetic characterization of factors required for vesicle formation.
Daniel J. Rioux+2 more
doaj +1 more source
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166
While several clathrin-independent endocytic processes have been described so far, their biological relevance often remains elusive, especially in pathophysiological contexts such as cancer.
Henri-François Renard+12 more
semanticscholar +1 more source