Results 221 to 230 of about 126,267 (387)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Arfs on the Golgi: four conductors, one orchestra. [PDF]

open access: yesFront Mol Biosci
Dejgaard SY, Presley JF.
europepmc   +1 more source

Clathrin-dependent endocytosis is required for immunity mediated by pattern recognition receptor kinases

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
Malick Mbengue   +10 more
semanticscholar   +1 more source

Packing of Clathrin into Coats

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1982
B. M. F. Pearse, R. A. Crowther
openaire   +3 more sources

Potent, Selective, and Drug‐like G Protein‐coupled Receptor Kinase 5 and 6 Inhibitors: Design, Synthesis, and X‐ray Structural Studies

open access: yesChemMedChem, Accepted Article.
We report here the design, synthesis, and evaluation of small molecules, drug‐like G protein‐coupled receptor kinase 5 (GRK5) inhibitors. GRK5 has become an important drug development target against heart failure and cancer. GRK6, a close homolog of GRK5, is considered as a possible therapeutic target for multiple myeloma.
Arun K Ghosh   +5 more
wiley   +1 more source

Dynamic early recruitment of GAK-Hsc70 regulates coated pit maturation. [PDF]

open access: yesProc Natl Acad Sci U S A
He Z   +9 more
europepmc   +1 more source

Forty Years of Clathrin‐coated Vesicles

open access: yesTraffic : the International Journal of Intracellular Transport, 2015
M. Robinson
semanticscholar   +1 more source

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