Results 21 to 30 of about 135,129 (369)

Clathrin exchange during clathrin-mediated endocytosis [PDF]

The Journal of Cell Biology, 2001
During clathrin-mediated endocytosis, clathrin-coated pits invaginate to form clathrin-coated vesicles (CVs). Since clathrin-coated pits are planar structures, whereas CVs are spherical, there must be a structural rearrangement of clathrin as invagination occurs.
Wu, Xufeng, Zhao, Xiaohong, Baylor, Lauren, Kaushal, Shivani, Eisenberg, Evan, Greene, Lois E.   +5 more
openaire   +2 more sources

The role of clathrin in post-golgi trafficking in toxoplasma gondii [PDF]

, 2013
Apicomplexan parasites are single eukaryotic cells with a highly polarised secretory system that contains unique secretory organelles (micronemes and rhoptries) that are required for host cell invasion.
Ferguson, D.J.P., Meissner, M., Pieperhoff, M.S., Schmitt, M.   +3 more
core   +13 more sources

Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo

Frontiers in Synaptic Neuroscience, 2022
Four modes of endocytosis and subsequent synaptic vesicle (SV) recycling have been described at the presynapse to ensure the availability of SVs for synaptic release.
Alp Paksoy, Simone Hoppe, Yvette Dörflinger, Heinz Horstmann, Kurt Sätzler, Christoph Körber   +5 more
doaj   +1 more source

Clathrin Adaptor GGA1 Polymerizes Clathrin into Tubules [PDF]

Journal of Biological Chemistry, 2007
GGAs, a class of monomeric clathrin adaptors, are involved in the sorting of cargo at the trans-Golgi network of eukaryotic cells. They are modular structures consisting of the VHS, the GAT, hinge, and GAE domains, which have been shown to interact directly with cargo, ARF, clathrin, and accessory proteins, respectively.
Fang, Zhang, Yang-In, Yim, Sarah, Scarselletta, Mark, Norton, Evan, Eisenberg, Lois E, Greene   +5 more
openaire   +2 more sources

Host Factors Genes BcCLC1 and BcCLC2 Confer Turnip Mosaic Virus Resistance in Non-Heading Chinese Cabbage (Brassica campestris ssp. chinensis)

Plants, 2023
Clathrin is an evolutionarily highly conserved evolutionary protein consisting of clathrin light chains (CLC) and clathrin heavy chains (CHC), and these form its basic structure. Clathrin is an important host factor in the process of viral infection.
Mengguo Yuan, Shanwu Lyu, Yaolong Wang, Liu E, Tongkun Liu, Xilin Hou, Ying Li, Changwei Zhang   +7 more
doaj   +1 more source

The structure and spontaneous curvature of clathrin lattices at the plasma membrane

bioRxiv, 2020
Clathrin mediated endocytosis is the primary pathway for receptor and cargo internalization in eukaryotic cells. It is characterized by a polyhedral clathrin lattice that coats budding membranes.
Kem A. Sochacki, Bridgette L. Heine, Gideon J Haber, J. Jimah, Bijeta Prasai, Marco A. Alfonzo-Méndez, Aleah D Roberts, Agila Somasundaram, J. Hinshaw, Justin W. Taraska   +9 more
semanticscholar   +1 more source

Hepatitis B virus entry into HepG2‐NTCP cells requires clathrin‐mediated endocytosis

Cellular Microbiology, 2020
Hepatitis B virus (HBV) is a leading cause of cirrhosis and hepatocellular carcinoma worldwide, with 250 million individuals chronically infected. Many stages of the HBV infectious cycle have been elucidated, but the mechanisms of HBV entry remain poorly
Charline Herrscher, Florentin Pastor, Julien Burlaud‐Gaillard, Amélie Dumans, Florian Seigneuret, A. Moreau, R. Patient, Sébastien Eymieux, H. de Rocquigny, C. Hourioux, P. Roingeard, Emmanuelle Blanchard   +11 more
semanticscholar   +1 more source

Hsc70-induced changes in clathrin-auxilin cage structure suggest a role for clathrin light chains in cage disassembly [PDF]

, 2013
The molecular chaperone, Hsc70, together with its co-factor, auxilin, facilitates the ATP-dependent removal of clathrin during clathrin-mediated endocytosis in cells.
Brodsky, Frances M., Harvey-Smith, Phillip, Kent, Helen, Pearse, Barbara M. F., Ranson, Neil, Roseman, Alan, Rothnie, Alice, Smith, Corinne J., Stoilova-McPhie, Svetla, Vallis, Yvonne, Young, Anna   +10 more
core   +2 more sources

Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166

Nature Communications, 2020
While several clathrin-independent endocytic processes have been described so far, their biological relevance often remains elusive, especially in pathophysiological contexts such as cancer.
Henri‐François Renard, François Tyckaert, Cristina Lo Giudice, Thibault Hirsch, C. A. Valades-Cruz, Camille Lemaigre, Massiullah Shafaq-Zadah, C. Wunder, R. Wattiez, L. Johannes, P. van der Bruggen, D. Alsteens, P. Morsomme   +12 more
semanticscholar   +1 more source

Characterization of a temperature-sensitive vertebrate clathrin heavy chain mutant as a tool to study clathrin-dependent events in vivo.

PLoS ONE, 2010
Clathrin and clathrin-dependent events are evolutionary conserved although it is believed that there are differences in the requirement for clathrin in yeast and higher vertebrates. Clathrin is a long-lived protein and thus, with clathrin knockdowns only
Petra Neumann-Staubitz, Stephanie L Hall, Joseph Kuo, Antony P Jackson   +3 more
doaj   +1 more source