Results 21 to 30 of about 63,639 (257)

SNX4 in complex with clathrin and dynein: implications for endosome movement. [PDF]

PLoS ONE, 2009
BACKGROUND:Sorting nexins (SNXs) constitute a family of proteins classified by their phosphatidylinositol (PI) binding Phox homology (PX) domain. Some members regulate intracellular trafficking.
Sigrid S Skånland, Sébastien Wälchli, Andreas Brech, Kirsten Sandvig   +3 more
doaj   +1 more source

Clathrin Light Chains: Not to Be Taken so Lightly

Frontiers in Cell and Developmental Biology, 2021
Clathrin is a cytosolic protein involved in the intracellular trafficking of a wide range of cargo. It is composed of three heavy chains and three light chains that together form a triskelion, the subunit that polymerizes to form a clathrin coated ...
Jyoti Das, Jyoti Das, Mahak Tiwari, Mahak Tiwari, Deepa Subramanyam   +4 more
doaj   +1 more source

Characterization of a temperature-sensitive vertebrate clathrin heavy chain mutant as a tool to study clathrin-dependent events in vivo.

PLoS ONE, 2010
Clathrin and clathrin-dependent events are evolutionary conserved although it is believed that there are differences in the requirement for clathrin in yeast and higher vertebrates. Clathrin is a long-lived protein and thus, with clathrin knockdowns only
Petra Neumann-Staubitz, Stephanie L Hall, Joseph Kuo, Antony P Jackson   +3 more
doaj   +1 more source

Clathrin is spindle-associated but not essential for mitosis.

PLoS ONE, 2008
BackgroundClathrin is a multimeric protein involved in vesicle coat assembly. Recently clathrin distribution was reported to change during the cell cycle and was found to associate with the mitotic spindle.
Joana Borlido, Greg Veltri, Antony P Jackson, Ian G Mills   +3 more
doaj   +1 more source

Large self-assembled clathrin lattices spontaneously disassemble without sufficient adaptor proteins.

PLoS Computational Biology, 2022
Clathrin-coated structures must assemble on cell membranes to internalize receptors, with the clathrin protein only linked to the membrane via adaptor proteins.
Si-Kao Guo, Alexander J Sodt, Margaret E Johnson   +2 more
doaj   +1 more source

Live-cell imaging of endocytosed synaptophysin around individual hippocampal presynaptic active zones

Frontiers in Cellular Neuroscience, 2023
In presynaptic terminals 4 types of endocytosis, kiss-and-run, clathrin-mediated, bulk and ultrafast endocytosis have been reported to maintain repetitive exocytosis of neurotransmitter. However, detailed characteristics and relative contribution of each
Hiromitsu Tanaka, Hiromitsu Tanaka, Junichiro Funahashi, Tomoo Hirano   +3 more
doaj   +1 more source

Vesicular stomatitis virus enters cells through vesicles incompletely coated with clathrin that depend upon actin for internalization.

PLoS Pathogens, 2009
Many viruses that enter cells by clathrin-dependent endocytosis are significantly larger than the dimensions of a typical clathrin-coated vesicle.
David K Cureton, Ramiro H Massol, Saveez Saffarian, Tomas L Kirchhausen, Sean P J Whelan   +4 more
doaj   +1 more source

Arabidopsis clathrin adaptor EPSIN1 but not MODIFIED TRANSPORT TO THE VACOULE1 contributes to effective plant immunity against pathogenic Pseudomonas bacteria

Plant Signaling & Behavior, 2023
In eukaryotes, EPSINs are Epsin N-terminal Homology (ENTH) domain-containing proteins that serve as monomeric clathrin adaptors at the plasma membrane (PM) or the trans-Golgi Network (TGN)/early endosomes (EE).
Kelly Mason, Erica LaMontagne-Mueller, Michael Sauer, Antje Heese   +3 more
doaj   +1 more source

Human Coronavirus 229E Uses Clathrin-Mediated Endocytosis as a Route of Entry in Huh-7 Cells

Biomolecules
Human coronavirus 229E (HCoV-229E) is an endemic coronavirus responsible for approximately one-third of “common cold” cases. To infect target cells, HCoV-229E first binds to its receptor on the cell surface and then can follow different pathways ...
Sabina Andreu, Inés Ripa, José Antonio López-Guerrero, Raquel Bello-Morales   +3 more
doaj   +1 more source

Role of Clathrin and Dynamin in Clathrin Mediated Endocytosis/Synaptic Vesicle Recycling and Implications in Neurological Diseases

Frontiers in Cellular Neuroscience, 2022
Endocytosis is a process essential to the health and well-being of cell. It is required for the internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of cell signalling.
Kate L. Prichard, Nicholas S. O'Brien, Sari R. Murcia, Jennifer R. Baker, Adam McCluskey   +4 more
doaj   +1 more source