Results 21 to 30 of about 126,267 (387)
Variability of Dynamin and Clathrin Dynamics in Clathrin Mediated Endocytosis [PDF]
Biophysical Journal, 2010 Clathrin mediated endocytosis (CME) is a pathway which internalizes receptors from the cell surface. The scission of clathrin coated vesicles from the plasma membrane requires dynamin. However, there are multiple models of dynamin mechanism without a consensus on the exact nature of its role.
Sanford M. Simon +2 more
openaire +2 more sources
Hsc70-induced changes in clathrin-auxilin cage structure suggest a role for clathrin light chains in cage disassembly [PDF]
, 2013 The molecular chaperone, Hsc70, together with its co-factor, auxilin, facilitates the ATP-dependent removal of clathrin during clathrin-mediated endocytosis in cells.
Brodsky, Frances M. +10 more
core +2 more sources
Clathrin-dependent endocytosis [PDF]
Biochemical Journal, 2004 The process by which clathrin-coated vesicles are produced involves interactions of multifunctional adaptor proteins with the plasma membrane, as well as with clathrin and several accessory proteins and phosphoinositides. Here we review recent findings highlighting new insights into mechanisms underlying clathrin-dependent endocytosis.
Rune Kjeken +3 more
openaire +3 more sources
PLoS ONE, 2010 Clathrin and clathrin-dependent events are evolutionary conserved although it is believed that there are differences in the requirement for clathrin in yeast and higher vertebrates. Clathrin is a long-lived protein and thus, with clathrin knockdowns only
Petra Neumann-Staubitz +3 more
doaj +1 more source
Bioengineering & Translational Medicine, 2023 Clathrin‐mediated endocytosis (CME) is an essential cell physiological process of broad biomedical relevance. Since the recent introduction of Pitstop‐2 as a potent CME inhibitor, we and others have reported on substantial clathrin‐independent inhibitory
Ivan Liashkovich +11 more
doaj +1 more source
Yeast Irc6p is a novel type of conserved clathrin coat accessory factor related to small G proteins. [PDF]
, 2012 Clathrin coat accessory proteins play key roles in transport mediated by clathrin-coated vesicles. Yeast Irc6p and the related mammalian p34 are putative clathrin accessory proteins that interact with clathrin adaptor complexes.
Cascio, Duilio +5 more
core +1 more source
Regulation of Clathrin-Mediated Endocytosis.
Annual Review of Biochemistry, 2018 Clathrin-mediated endocytosis (CME) is the major endocytic pathway in mammalian cells. It is responsible for the uptake of transmembrane receptors and transporters, for remodeling plasma membrane composition in response to environmental changes, and for ...
Marcel Mettlen +4 more
semanticscholar +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1998 Clathrin and adaptors are components of clathrin-coated pits and vesicles. The AP-1 adaptor complex is associated with clathrin-coated vesicles budding from the TGN, while the AP-2 adaptor complex is associated with clathrin-coated vesicles budding from the plasma membrane. The clathrin forms a polyhedral lattice and is believed to be the driving force
Margaret S. Robinson, Jennifer Hirst
openaire +2 more sources
Clathrin is spindle-associated but not essential for mitosis.
PLoS ONE, 2008 BackgroundClathrin is a multimeric protein involved in vesicle coat assembly. Recently clathrin distribution was reported to change during the cell cycle and was found to associate with the mitotic spindle.
Joana Borlido +3 more
doaj +1 more source
Membrane Heterogeneity Controls Cellular Endocytic Trafficking
Frontiers in Cell and Developmental Biology, 2020 Endocytic trafficking relies on highly localized events in cell membranes. Endocytosis involves the gathering of protein (cargo/receptor) at distinct plasma membrane locations defined by specific lipid and protein compositions.
Gregory M. I. Redpath +7 more
doaj +1 more source