Results 41 to 50 of about 126,267 (387)

The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. [PDF]

, 2012
The PICALM (CALM) gene, whose product is involved in clathrin-mediated endocytosis, has been identified in two recurring chromosomal translocations, involving either MLL or MLLT10 (AF10). We developed a mouse model of CALM-AF10(+) leukemia to examine the
Anastasi, J, Brodsky, FM, Fernald, AA, Le Beau, MM, Stoddart, A, Tennant, TR   +5 more
core   +2 more sources

Clathrin Light Chains: Not to Be Taken so Lightly

Frontiers in Cell and Developmental Biology, 2021
Clathrin is a cytosolic protein involved in the intracellular trafficking of a wide range of cargo. It is composed of three heavy chains and three light chains that together form a triskelion, the subunit that polymerizes to form a clathrin coated ...
Jyoti Das, Jyoti Das, Mahak Tiwari, Mahak Tiwari, Deepa Subramanyam   +4 more
doaj   +1 more source

Clathrin-independent pathways do not contribute significantly to endocytic flux

eLife, 2014
Several different endocytic pathways have been proposed to function in mammalian cells. Clathrin-coated pits are well defined, but the identity, mechanism and function of alternative pathways have been controversial.
Vassilis Bitsikas, Ivan R Corrêa Jr, Benjamin J Nichols   +2 more
doaj   +1 more source

Dynamin recruitment by clathrin coats: a physical step? [PDF]

, 2003
Recent structural findings have shown that dynamin, a cytosol protein playing a key-role in clathrin-mediated endocytosis, inserts partly within the lipid bilayer and tends to self-assemble around lipid tubules. Taking into account these observations, we
Dommersnes, P. -G., Fournier, J. -B., Galatola, P.   +2 more
core   +2 more sources

Clathrin-adaptor ratio and membrane tension regulate the flat-to-curved transition of the clathrin coat during endocytosis

Nature Communications, 2018
Although essential for many cellular processes, the sequence of structural and molecular events during clathrin-mediated endocytosis remains elusive. While it was long believed that clathrin-coated pits grow with a constant curvature, it was recently ...
Delia Bucher, F. Frey, Kem A. Sochacki, Susann Kummer, Jan-Philip Bergeest, William J. Godinez, H. Kräusslich, K. Rohr, Justin W. Taraska, U. Schwarz, S. Boulant   +10 more
semanticscholar   +1 more source

Evaluation of the role of clathrin and bacterial viability in the endocytosis of Lawsonia intracellularis

Frontiers in Veterinary Science, 2023
Lawsonia intracellularis is an obligate intracellular bacterium and causative agent of proliferative enteropathy. The pathogenesis of L. intracellularis is not completely understood, including the endocytic mechanisms to access the host cell cytoplasm ...
Carlos Eduardo Real Pereira, Carlos Eduardo Real Pereira, Talita Pilar Resende, Amanda Gabrielle de Souza Daniel, Amanda Gabrielle de Souza Daniel, Fabio Augusto Vannucci, Connie Gebhart, Roberto Mauricio Carvalho Guedes   +7 more
doaj   +1 more source

Membrane remodeling in clathrin-mediated endocytosis

Journal of Cell Science, 2018
Clathrin-mediated endocytosis is an essential cellular mechanism by which all eukaryotic cells regulate their plasma membrane composition to control processes ranging from cell signaling to adhesion, migration and morphogenesis.
V. Haucke, M. Kozlov
semanticscholar   +1 more source

High-resolution three-dimensional views of membrane-associated clathrin and cytoskeleton in critical-point-dried macrophages. [PDF]

, 1983
We obtained high-resolution topographical information about the distribution of clathrin and cytoskeletal filaments on cytoplasmic membrane surfaces of macrophages spreading onto glass coverslips by both critical-point drying of broken-open cells and ...
Aggeler, J, Takemura, R, Werb, Z
core   +1 more source

Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self assembly

Nature Structural & Molecular Biology, 2019
Clathrin forms diverse lattice and cage structures that change size and shape rapidly in response to the needs of eukaryotic cells during clathrin-mediated endocytosis and intracellular trafficking. We present the cryo-EM structure and molecular model of
Kyle L. Morris, Joseph R. Jones, Mary Halebian, Shenping Wu, Michael Baker, J. Armache, Amaurys Avila Ibarra, R. Sessions, A. Cameron, Yifan Cheng, Corinne J. Smith   +10 more
semanticscholar   +1 more source

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +6 more sources