Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]
, 2018 Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska +75 more
core +8 more sources
Clathrin-independent endocytosis: an increasing degree of complexity
Histochemistry and Cell Biology, 2018 This article aims at providing an update on the complexity of clathrin-independent endocytosis. It is now almost 30 years since we first wrote a review about its existence; at that time many people believed that with the exception of macropinocytosis ...
K. Sandvig +2 more
semanticscholar +1 more source
Clathrin Adaptor Complex-interacting Protein Irc6 Functions through the Conserved C-Terminal Domain. [PDF]
, 2019 Clathrin coats drive transport vesicle formation from the plasma membrane and in pathways between the trans-Golgi network (TGN) and endosomes. Clathrin adaptors play central roles orchestrating assembly of clathrin coats.
Costaguta, Giancarlo +2 more
core +2 more sources
Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self assembly
Nature Structural & Molecular Biology, 2019 Clathrin forms diverse lattice and cage structures that change size and shape rapidly in response to the needs of eukaryotic cells during clathrin-mediated endocytosis and intracellular trafficking. We present the cryo-EM structure and molecular model of
Kyle L. Morris +10 more
semanticscholar +1 more source
PLoS Computational Biology, 2022 Clathrin-coated structures must assemble on cell membranes to internalize receptors, with the clathrin protein only linked to the membrane via adaptor proteins.
Si-Kao Guo +2 more
doaj +1 more source
High-resolution three-dimensional views of membrane-associated clathrin and cytoskeleton in critical-point-dried macrophages. [PDF]
, 1983 We obtained high-resolution topographical information about the distribution of clathrin and cytoskeletal filaments on cytoplasmic membrane surfaces of macrophages spreading onto glass coverslips by both critical-point drying of broken-open cells and ...
Aggeler, J, Takemura, R, Werb, Z
core +1 more source
Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2
Journal of Cell Biology, 2017 The critical initiation phase of clathrin-mediated endocytosis (CME) determines where and when endocytosis occurs. Heterotetrameric adaptor protein 2 (AP2) complexes, which initiate clathrin-coated pit (CCP) assembly, are activated by conformational ...
Z. Kadlecová +5 more
semanticscholar +1 more source
The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. [PDF]
, 2012 The PICALM (CALM) gene, whose product is involved in clathrin-mediated endocytosis, has been identified in two recurring chromosomal translocations, involving either MLL or MLLT10 (AF10). We developed a mouse model of CALM-AF10(+) leukemia to examine the
Anastasi, J +5 more
core +2 more sources
Evidence for ESCRT- and clathrin-dependent microautophagy
Journal of Cell Biology, 2017 Microautophagy refers to a mode of autophagy in which the lysosomal or vacuolar membrane invaginates and directly engulfs target components. The molecular machinery of membrane dynamics driving microautophagy is still elusive.
Masahide Oku +6 more
semanticscholar +1 more source
PLoS Pathogens, 2009 Many viruses that enter cells by clathrin-dependent endocytosis are significantly larger than the dimensions of a typical clathrin-coated vesicle.
David K Cureton +4 more
doaj +1 more source