Results 261 to 270 of about 79,602 (359)

Single-cell multi-omic profiling of heterogeneous PROCR⁺ cells in mouse mammary gland and its implication for breast cancer. [PDF]

iScience
Yan KK, Nekritz E, Xie Z, Ju B, Dong X, Werner R, Alsina-Beauchamp D, Rosencrance C, Mukhopadhyay P, Pan Q, Gorbatenko A, Zhou H, Yan L, Ding L, Qian C, Natarajan S, Chi H, Easton J, Silva J, Yu J.   +19 more
europepmc   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

FK228-Mediated Restoration of Tight Junction Proteins in Diabetic Neuropathy. [PDF]

Biology (Basel)
Chen E, Thakur V, Chowdhury E, Misra A, Valdez C, Chattopadhyay M.   +5 more
europepmc   +1 more source

Claudin-6 [PDF]

, 2020
openaire   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Supplementation with Yellow Mealworm (<i>Tenebrio molitor</i>) Larvae Grown on Deoxynivalenol-Contaminated Substrate Improves Growth and Gut Integrity in Broilers. [PDF]

Toxins (Basel)
Shanmugasundaram R, McCafferty KW, Kappari L, Ye X, Robinson K, Glenn AE.   +5 more
europepmc   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

<i>Bifidobacterium longum</i> Subspecies <i>infantis</i> M63 Enhances the Colitis-Alleviating Effect of 2'-Fucosyllactose by Restoring Intestinal Barrier Function and Microbial Metabolism. [PDF]

Foods
Zhang H, Li X, Tan M, Bao Y, Jiang S.
europepmc   +1 more source

Predicted microbiome‐associated metabolic pathways are linked to immune checkpoint modulation in chronic lymphocytic leukaemia

British Journal of Haematology, EarlyView.
Summary Microbial metabolites are key regulators of host immunity, yet their functional impact in chronic lymphocytic leukaemia (CLL) remains unclear. Following up on our earlier observations of microbiome dysbiosis in CLL, we performed predictive metabolic profiling based on 16S ribosomal RNA (rRNA) sequencing of oral and stool samples collected from ...
Monika Szelest, Joanna Zaleska, Michał Kiełbus, Magdalena Paziewska, Marta Masternak, Ewa Wawrzyniak, Aleksandra Kotkowska, Monika Siemieniuk‐Ryś, Marta Morawska, Elżbieta Kalicińska, Paula Jabłonowska‐Babij, Tomasz Wróbel, Anna Wolska‐Washer, Jerzy Zdzisław Błoński, Tadeusz Robak, Krzysztof Giannopoulos   +15 more
wiley   +1 more source

Polysaccharide from Atractylodes macrocephala Koidz. protects against avian pathogenic Escherichia coli-induced intestinal barrier Dysfunction via Suppressing PI3K/Akt-Mediated Claudin-2 upregulation. [PDF]

Poult Sci
Chen S, Qu X, Wu J.
europepmc   +1 more source